Curriculum vitae
CAROLINA SIMIONI
CURRENT POSITION
Associate Professor SSD MEDS-26/A - Laboratory Medicine Technical Sciences, Department of Life Sciences and Biotechnology, University of Ferrara
PREVIOUS POSITIONS
2018- 2021: Researcher (RTD-A, SSD MEDS-20/A), Department of Medical Sciences, University of Ferrara
2021- 2024: Researcher (RTD-B, SSD MEDS-26/A), Department of Life Sciences and Biotechnology, University of Ferrara.
EDUCATIONAL QUALIFICATIONS
- 07/04: Bachelor's degree in Molecular Biology, University of Padua
- 07/06: Master's degree in Biomolecular and Cellular Sciences, University of Ferrara
- 03/10: PhD in Pharmacology and Molecular Oncology, University of Ferrara
TEACHING ACTIVITIES
Professor of Anatomy and Pathological Histology for the Degree Course in Biomedical Laboratory Techniques, University of Ferrara
Professor of Morphological Techniques and Experimental Applications for the Degree Course in Biotechnology for Translational Medicine, University of Ferrara
Professor of Anatomy I for the Degree Course in Medicine and Surgery, University of Ferrara
MANAGEMENT ACTIVITIES
- Member of the Italian Society of Anatomy and Histology (SIAI)
- Member of the Italian Society of Histochemistry (SII)
SCIENTIFIC PROFILE
Orcid ID: https://orcid.org/0000-0003-0801-7811
Scopus Author ID: 17347392700
Overall scientific production and Bibliometric Indicators calculated as of 13/01/2025
- Number of scientific papers published in international journals with board of referees: 32
- Total number of citations: 1707
- Hirsch/H-index: 21 (from source: Scopus)
Main Research Topics
- Innovative therapeutic approaches in oncohematology: studies using leukemia cell models, particularly acute lymphoblastic leukemia and solid tumor models such as hepatocarcinoma and breast cancer cell lines.
- Role of microRNAs in oncohematology: studies focused on microRNA analysis employing acute lymphoblastic leukemia cell lines and solid tumor models such as hepatocarcinoma and breast cancer cell lines. The present research also includes the study of circulating microRNAs in urinary and blood samples from cancer patients and long-term survivors.
- Studies of intracellular signal transduction pathways and epigenetic modulation in the tumor microenvironment
- Role of microRNAs in corneal samples from patients affected by keratoconus
Major research projects
- University funds for research projects funded by 5 X 1000 grant year 2018. Project: 'Morphological and structural characterization of biomarkers related to COVID-19-induced vascular damage in patients with diseases related to thrombotic processes'.
- Research project funded under ROP ERDF 2014-2020 calls , Project title: “BiophotOmics: development and pilot validation of portable bio-photonic imaging medical device integrated with lipidomic testing methodology”.
- FIRD Project (Year 2022). Project title: “Role of dysfunctional adipocyte-derived miRNAs and importance of nutraceutical supplementation treatment as a tool for prevention at breast cancer initiation.”
- FIRD Project (Year 2023). Project title: “The role of epigenetics in acute lymphoblastic leukemia: analysis of the molecular biological profile and cellular mechanisms involved in the development of the neoplasm.”
- FIRD Project (Year 2024). Project title: “Role of DNA methyltransferase and histone deacetylase inhibitors in tumor models: analysis of the cellular mechanisms involved and modulation of signal transduction pathways characterizing the tumor microenvironment.”
TECHNOLOGY TRANSFER ACTIVITIES
Prof. Simioni collaborates in the activities of the Technopole Laboratory for Advanced Therapy Technologies (LTTA) of the University of Ferrara for the use of different facilities to support genomic and post-genomic investigations in neoplastic and cardiovascular diseases and for the development of preclinical tests on in vitro and in vivo systems.
CAROLINA SIMIONI
CURRENT POSITION
Associate Professor SSD MEDS-26/A - Laboratory Medicine Technical Sciences, Department of Life Sciences and Biotechnology, University of Ferrara
PREVIOUS POSITIONS
2018- 2021: Researcher (RTD-A, SSD MEDS-20/A), Department of Medical Sciences, University of Ferrara
2021- 2024: Researcher (RTD-B, SSD MEDS-26/A), Department of Life Sciences and Biotechnology, University of Ferrara.
EDUCATIONAL QUALIFICATIONS
- 07/04: Bachelor's degree in Molecular Biology, University of Padua
- 07/06: Master's degree in Biomolecular and Cellular Sciences, University of Ferrara
- 03/10: PhD in Pharmacology and Molecular Oncology, University of Ferrara
TEACHING ACTIVITIES
Professor of Anatomy and Pathological Histology for the Degree Course in Biomedical Laboratory Techniques, University of Ferrara
Professor of Morphological Techniques and Experimental Applications for the Degree Course in Biotechnology for Translational Medicine, University of Ferrara
Professor of Anatomy I for the Degree Course in Medicine and Surgery, University of Ferrara
MANAGEMENT ACTIVITIES
- Member of the Italian Society of Anatomy and Histology (SIAI)
- Member of the Italian Society of Histochemistry (SII)
SCIENTIFIC PROFILE
Orcid ID: https://orcid.org/0000-0003-0801-7811
Scopus Author ID: 17347392700
Overall scientific production and Bibliometric Indicators calculated as of 13/01/2025
- Number of scientific papers published in international journals with board of referees: 32
- Total number of citations: 1707
- Hirsch/H-index: 21 (from source: Scopus)
Main Research Topics
- Innovative therapeutic approaches in oncohematology: studies using leukemia cell models, particularly acute lymphoblastic leukemia and solid tumor models such as hepatocarcinoma and breast cancer cell lines.
- Role of microRNAs in oncohematology: studies focused on microRNA analysis employing acute lymphoblastic leukemia cell lines and solid tumor models such as hepatocarcinoma and breast cancer cell lines. The present research also includes the study of circulating microRNAs in urinary and blood samples from cancer patients and long-term survivors.
- Studies of intracellular signal transduction pathways and epigenetic modulation in the tumor microenvironment
- Role of microRNAs in corneal samples from patients affected by keratoconus
Major research projects
- University funds for research projects funded by 5 X 1000 grant year 2018. Project: 'Morphological and structural characterization of biomarkers related to COVID-19-induced vascular damage in patients with diseases related to thrombotic processes'.
- Research project funded under ROP ERDF 2014-2020 calls , Project title: “BiophotOmics: development and pilot validation of portable bio-photonic imaging medical device integrated with lipidomic testing methodology”.
- FIRD Project (Year 2022). Project title: “Role of dysfunctional adipocyte-derived miRNAs and importance of nutraceutical supplementation treatment as a tool for prevention at breast cancer initiation.”
- FIRD Project (Year 2023). Project title: “The role of epigenetics in acute lymphoblastic leukemia: analysis of the molecular biological profile and cellular mechanisms involved in the development of the neoplasm.”
- FIRD Project (Year 2024). Project title: “Role of DNA methyltransferase and histone deacetylase inhibitors in tumor models: analysis of the cellular mechanisms involved and modulation of signal transduction pathways characterizing the tumor microenvironment.”
TECHNOLOGY TRANSFER ACTIVITIES
Prof. Simioni collaborates in the activities of the Technopole Laboratory for Advanced Therapy Technologies (LTTA) of the University of Ferrara for the use of different facilities to support genomic and post-genomic investigations in neoplastic and cardiovascular diseases and for the development of preclinical tests on in vitro and in vivo systems.
