2006: Master's degree in Biomolecular and Cellular Sciences from the University of Ferrara, with a grade of 110/110 cum laude
2007-2009: PhD student, with project aimed at the characterization of adenosine receptor agonists and antagonists in preclinical cancer models at the Department of Clinical and Experimental Medicine, University of Ferrara
2010: Attainment of PhD degree in Pharmacology and Molecular Oncology at the University of Ferrara
January 2010- December 2010: Holder of fellowship for Project Collaboration at the Department of Clinical and Experimental Medicine, University of Ferrara
January 2011- March 2011: Fellowship holder at the Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
April 2011- April 2014: Holder of a Coordinated and Continuing Postdoctoral Fellowship at the Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
May 2014- April 2018: Research grant holder at the Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
September 2018- February 2021: Type A fixed-term researcher (RTD-A, SSD MED/38) at the Department of Medical Sciences, University of Ferrara
March 2021- February 2024: Type B fixed-term researcher (RTD-B, SSD MEDS-26/A, formerly MED/46) at the Department of Life Sciences and Biotechnology, University of Ferrara.
March 2024- Today: Associate Professor SSD MEDS-26/A - Laboratory Medicine Technical Sciences, at the Department of Life Sciences and Biotechnology, University of Ferrara
SCIENTIFIC ACTIVITY
Prof. Simioni's research activity has mainly focused on the analysis of the intracellular mechanisms and pathways involved in the processes of proliferation, differentiation and apoptosis in different oncohematological cell models, in ex vivo samples of placentas or of patients with vascular diseases, particularly with viral etiology by Covid-19. The main areas of interest are outlined below:
-Innovative therapeutic approaches in onco-hematology: studies using leukemia cell models, particularly acute lymphoblastic leukemia, and solid tumor models such as hepatocarcinoma.
- Role of microRNAs in oncohematology: studies focused on microRNA analysis employing acute lymphoblastic leukemia cell lines and transgenic mouse models highly predisposed to the development of hepatocarcinoma. The present line of research currently also includes the search for circulating microRNAs in urinary and blood samples from cancer patients and long-term survivors.
- Analysis of clinical biomarkers associated with SARS-CoV-2 infection: studies aimed at characterizing gut-level damage in surgical patients operated in emergency and during SARS-CoV-2 infection and identifying biomarkers predictors of clinical outcomes.
SCIENTIFIC PROFILE
Orcid ID: https://orcid.org/0000-0003-0801-7811
Scopus Author ID: 17347392700
Overall scientific production and Bibliometric Indicators calculated as of 01/13/2025
- Number of scientific papers published in international journals with board of referees: 32
- Total number of citations: 1707
- Hirsch/H-index: 21 (from source: Scopus)
TECHNOLOGY TRANSFER ACTIVITIES
Prof. Simioni collaborates in the activities of the Technopole Laboratory for Advanced Therapy Technologies (LTTA) of the University of Ferrara for the use of the different facilities to support genomic and post-genomic investigations in neoplastic and cardiovascular diseases and for the development of preclinical tests on in vitro and in vivo systems.
2007-2009: PhD student, with project aimed at the characterization of adenosine receptor agonists and antagonists in preclinical cancer models at the Department of Clinical and Experimental Medicine, University of Ferrara
2010: Attainment of PhD degree in Pharmacology and Molecular Oncology at the University of Ferrara
January 2010- December 2010: Holder of fellowship for Project Collaboration at the Department of Clinical and Experimental Medicine, University of Ferrara
January 2011- March 2011: Fellowship holder at the Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
April 2011- April 2014: Holder of a Coordinated and Continuing Postdoctoral Fellowship at the Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
May 2014- April 2018: Research grant holder at the Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
September 2018- February 2021: Type A fixed-term researcher (RTD-A, SSD MED/38) at the Department of Medical Sciences, University of Ferrara
March 2021- February 2024: Type B fixed-term researcher (RTD-B, SSD MEDS-26/A, formerly MED/46) at the Department of Life Sciences and Biotechnology, University of Ferrara.
March 2024- Today: Associate Professor SSD MEDS-26/A - Laboratory Medicine Technical Sciences, at the Department of Life Sciences and Biotechnology, University of Ferrara
SCIENTIFIC ACTIVITY
Prof. Simioni's research activity has mainly focused on the analysis of the intracellular mechanisms and pathways involved in the processes of proliferation, differentiation and apoptosis in different oncohematological cell models, in ex vivo samples of placentas or of patients with vascular diseases, particularly with viral etiology by Covid-19. The main areas of interest are outlined below:
-Innovative therapeutic approaches in onco-hematology: studies using leukemia cell models, particularly acute lymphoblastic leukemia, and solid tumor models such as hepatocarcinoma.
- Role of microRNAs in oncohematology: studies focused on microRNA analysis employing acute lymphoblastic leukemia cell lines and transgenic mouse models highly predisposed to the development of hepatocarcinoma. The present line of research currently also includes the search for circulating microRNAs in urinary and blood samples from cancer patients and long-term survivors.
- Analysis of clinical biomarkers associated with SARS-CoV-2 infection: studies aimed at characterizing gut-level damage in surgical patients operated in emergency and during SARS-CoV-2 infection and identifying biomarkers predictors of clinical outcomes.
SCIENTIFIC PROFILE
Orcid ID: https://orcid.org/0000-0003-0801-7811
Scopus Author ID: 17347392700
Overall scientific production and Bibliometric Indicators calculated as of 01/13/2025
- Number of scientific papers published in international journals with board of referees: 32
- Total number of citations: 1707
- Hirsch/H-index: 21 (from source: Scopus)
TECHNOLOGY TRANSFER ACTIVITIES
Prof. Simioni collaborates in the activities of the Technopole Laboratory for Advanced Therapy Technologies (LTTA) of the University of Ferrara for the use of the different facilities to support genomic and post-genomic investigations in neoplastic and cardiovascular diseases and for the development of preclinical tests on in vitro and in vivo systems.
