Pubblicazioni

La produzione scientifica del dott. Massimo Tacchini si caratterizza in 55 articoli pubblicati su riviste internazionali peer-reviewed (sotto riportati), e 2 pubblicazioni di carattere divulgativo.

1.

Nilofar; Ahmed, S.; Zengin, G.; Di Simone, S.C.; Acquaviva, A.; Libero, M.L.; Chiavaroli, A.; Orlando, G.; Tacchini, M.; Di Vito, M.; et al. Combining the Pharmaceutical and Toxicological Properties of Selected Essential Oils with Their Chemical Components by GC‐MS Analysis. Chemistry & Biodiversity 2024, 21, e202400738, doi:10.1002/cbdv.202400738.

2.

Giorni, P.; Bulla, G.; Leni, G.; Soldano, M.; Tacchini, M.; Guerrini, A.; Sacchetti, G.; Bertuzzi, T. Enhancement of Agri-Food by-Products: Green Extractions of Bioactive Molecules with Fungicidal Action against Mycotoxigenic Fungi and Their Mycotoxins. Front. Nutr. 2023, 10, 1196812, doi:10.3389/fnut.2023.1196812.

3.

Melloni, E.; Grassilli, S.; Romani, A.; Rimondi, E.; Marcuzzi, A.; Zauli, E.; Secchiero, P.; Paganetto, G.; Guerrini, A.; Sacchetti, G.; et al. Convolvulus Pluricaulis Choisy’s Extraction, Chemical Characterization and Evaluation of the Potential Effects on Glycaemic Balance in a 3T3-L1 Adipocyte Cell Model. Nutrients 2023, 15, 1727, doi:10.3390/nu15071727.

4.

Chiocchio, I.; Mandrone, M.; Tacchini, M.; Guerrini, A.; Poli, F. Phytochemical Profile and In Vitro Bioactivities of Plant-Based By-Products in View of a Potential Reuse and Valorization. Plants 2023, 12, 795, doi:10.3390/plants12040795.

5.

Guerrini, A.; Tacchini, M.; Chiocchio, I.; Grandini, A.; Radice, M.; Maresca, I.; Paganetto, G.; Sacchetti, G. A Comparative Study on Chemical Compositions and Biological Activities of Four Amazonian Ecuador Essential Oils: Curcuma Longa L. (Zingiberaceae), Cymbopogon Citratus (DC.) Stapf, (Poaceae), Ocimum Campechianum Mill. (Lamiaceae), and Zingiber Officinale Roscoe (Zingiberaceae). Antibiotics 2023, 12, 177, doi:10.3390/antibiotics12010177.

6.

Tacchini, M.; Sacchetti, G.; Guerrini, A.; Paganetto, G. Mycochemicals against Cancer Stem Cells. Toxins 2023, 15, 360, doi:10.3390/toxins15060360.

7.

Lenzi, M.; Turrini, E.; Catanzaro, E.; Cocchi, V.; Guerrini, A.; Hrelia, P.; Gasperini, S.; Stefanelli, C.; Abdi Bellau, M.L.; Pellicioni, V.; et al. In Vitro Investigation of the Anticancer Properties of Ammodaucus Leucotrichus Coss. & Dur. Pharmaceuticals 2022, 15, 1491, doi:10.3390/ph15121491.

8.

Di Sotto, A.; Gullì, M.; Acquaviva, A.; Tacchini, M.; Di Simone, S.C.; Chiavaroli, A.; Recinella, L.; Leone, S.; Brunetti, L.; Orlando, G.; et al. Phytochemical and Pharmacological Profiles of the Essential Oil from the Inflorescences of the Cannabis Sativa L. Industrial Crops and Products 2022, 183, 114980, doi:10.1016/j.indcrop.2022.114980.

9.

Abdi Bellau, M.L.; Chiurato, M.A.; Maietti, A.; Fantin, G.; Tedeschi, P.; Marchetti, N.; Tacchini, M.; Sacchetti, G.; Guerrini, A. Nutrients and Main Secondary Metabolites Characterizing Extracts and Essential Oil from Fruits of Ammodaucus Leucotrichus Coss. & Dur. (Western Sahara). Molecules 2022, 27, 5013, doi:10.3390/molecules27155013.

10.

Saab, A.M.; Tacchini, M.; Sacchetti, G.; Contini, C.; Schulz, H.; Lampronti, I.; Gambari, R.; Makhlouf, H.; Tannoury, M.; Venditti, A.; et al. Phytochemical Analysis and Potential Natural Compounds against SARS-CoV-2/COVID-19 in Essential Oils Derived from Medicinal Plants Originating from Lebanon. An Information Note. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 2022, 156, 855–864, doi:10.1080/11263504.2021.1932629.

11.

Guardado Yordi, E.; Matos, M.J.; Buso, P.; Martínez, A.P.; Asanza, M.; Scalvenzi, L.; Manfredini, S.; Tacchini, M.; Radice, M.; Sacchetti, G. A Comprehensive Ethnobotanical Profile of Ocimum Campechianum (Lamiaceae): From Traditional Medicine to Phytochemical and Pharmacological Evidences. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 2022, 1–17, doi:10.1080/11263504.2022.2056647.

12.

Di Simone, S.C.; Acquaviva, A.; Libero, M.L.; Chiavaroli, A.; Recinella, L.; Leone, S.; Brunetti, L.; Politi, M.; Giannone, C.; Campana, C.; et al. The Association of Tanacetum Parthenium and Salix Alba Extracts Reduces Cortex Serotonin Turnover, in an Ex Vivo Experimental Model of Migraine. Processes 2022, 10, 280, doi:10.3390/pr10020280.

13.

Capetti, F.; Tacchini, M.; Marengo, A.; Cagliero, C.; Bicchi, C.; Rubiolo, P.; Sgorbini, B. Citral-Containing Essential Oils as Potential Tyrosinase Inhibitors: A Bio-Guided Fractionation Approach. Plants 2021, 10, 969, doi:10.3390/plants10050969.

14.

Greco, G.; Turrini, E.; Tacchini, M.; Maresca, I.; Fimognari, C. The Alcoholic Bark Extract of Terminalia Arjuna Exhibits Cytotoxic and Cytostatic Activity on Jurkat Leukemia Cells. VAT 2021, 1, 56–66, doi:10.2174/2666121701999200601170928.

15.

Guerrini, A.; Sacchetti, G.; Echeverria Guevara, M.P.; Paganetto, G.; Grandini, A.; Maresca, I.; Menghini, L.; Di Martino, L.; Marengo, A.; Tacchini, M. Wild Italian Hyssopus Officinalis Subsp. Aristatus (Godr.) Nyman: From Morphological and Phytochemical Evidences to Biological Activities. Plants 2021, 10, 631, doi:10.3390/plants10040631.

16.

Orlando, G.; Adorisio, S.; Delfino, D.; Chiavaroli, A.; Brunetti, L.; Recinella, L.; Leone, S.; D’Antonio, M.; Zengin, G.; Acquaviva, A.; et al. Comparative Investigation of Composition, Antifungal, and Anti-Inflammatory Effects of the Essential Oil from Three Industrial Hemp Varieties from Italian Cultivation. Antibiotics 2021, 10, 334, doi:10.3390/antibiotics10030334.

17.

Mahomoodally, M.F.; Jugreet, S.; Sinan, K.I.; Zengin, G.; Ak, G.; Ceylan, R.; Jekő, J.; Cziáky, Z.; Angelini, P.; Angeles Flores, G.; et al. Pharmacological Potential and Chemical Characterization of Bridelia Ferruginea Benth.—A Native Tropical African Medicinal Plant. Antibiotics 2021, 10, 223, doi:10.3390/antibiotics10020223.

18.

Menghini, L.; Ferrante, C.; Carradori, S.; D’Antonio, M.; Orlando, G.; Cairone, F.; Cesa, S.; Filippi, A.; Fraschetti, C.; Zengin, G.; et al. Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil. Biomolecules 2021, 11, 272, doi:10.3390/biom11020272.

19.

Sinan, K.I.; Ak, G.; Etienne, O.K.; Jekő, J.; Cziáky, Z.; Gupcsó, K.; João Rodrigues, M.; Custodio, L.; Mahomoodally, M.F.; Sharmeen, J.B.; et al. Deeper Insights on Alchornea Cordifolia (Schumach. & Thonn.) Müll.Arg Extracts: Chemical Profiles, Biological Abilities, Network Analysis and Molecular Docking. Biomolecules 2021, 11, 219, doi:10.3390/biom11020219.

20.

Mandrone, M.; Chiocchio, I.; Barbanti, L.; Tomasi, P.; Tacchini, M.; Poli, F. Metabolomic Study of Sorghum ( Sorghum Bicolor ) to Interpret Plant Behavior under Variable Field Conditions in View of Smart Agriculture Applications. J. Agric. Food Chem. 2021, 69, 1132–1145, doi:10.1021/acs.jafc.0c06533.

21.

Tacchini, M.; Echeverria Guevara, M.P.; Grandini, A.; Maresca, I.; Radice, M.; Angiolella, L.; Guerrini, A. Ocimum Campechianum Mill. from Amazonian Ecuador: Chemical Composition and Biological Activities of Extracts and Their Main Constituents (Eugenol and Rosmarinic Acid). Molecules 2020, 26, 84, doi:10.3390/molecules26010084.

22.

Guerrini, A.; Burlini, I.; Huerta Lorenzo, B.; Grandini, A.; Vertuani, S.; Tacchini, M.; Sacchetti, G. Antioxidant and Antimicrobial Extracts Obtained from Agricultural By-Products: Strategies for a Sustainable Recovery and Future Perspectives. Food and Bioproducts Processing 2020, 124, 397–407, doi:10.1016/j.fbp.2020.10.003.

23.

Baldisserotto, A.; Demurtas, M.; Lampronti, I.; Tacchini, M.; Moi, D.; Balboni, G.; Vertuani, S.; Manfredini, S.; Onnis, V. In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives. Pharmaceuticals 2020, 13, 68, doi:10.3390/ph13040068.

24.

Burlini, I.; Grandini, A.; Tacchini, M.; Maresca, I.; Guerrini, A.; Sacchetti, G. Different Strategies to Obtain Corn ( Zea Mays L.) Germ Extracts with Enhanced Antioxidant Properties. Natural Product Communications 2020, 15, 1934578X2090356, doi:10.1177/1934578X20903562.

25.

Baldisserotto, A.; Demurtas, M.; Lampronti, I.; Tacchini, M.; Moi, D.; Balboni, G.; Pacifico, S.; Vertuani, S.; Manfredini, S.; Onnis, V. Synthesis and Evaluation of Antioxidant and Antiproliferative Activity of 2-Arylbenzimidazoles. Bioorganic Chemistry 2020, 94, 103396, doi:10.1016/j.bioorg.2019.103396.

26.

Turrini, E.; Catanzaro, E.; Ferruzzi, L.; Guerrini, A.; Tacchini, M.; Sacchetti, G.; Paganetto, G.; Maffei, F.; Pellicioni, V.; Poli, F.; et al. Hemidesmus Indicus Induces Apoptosis via Proteasome Inhibition and Generation of Reactive Oxygen Species. Sci Rep 2019, 9, 7199, doi:10.1038/s41598-019-43609-5.

27.

Tacchini, M.; Burlini, I.; Bernardi, T.; De Risi, C.; Massi, A.; Guerrini, A.; Sacchetti, G. Chemical Characterisation, Antioxidant and Antimicrobial Screening for the Revaluation of Wine Supply Chain by-Products Oriented to Circular Economy. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 2019, 153, 809–816, doi:10.1080/11263504.2018.1549614.

28.

Bernardi, T.; Bortolini, O.; Massi, A.; Sacchetti, G.; Tacchini, M.; De Risi, C. Exploring the Synergy Between HPTLC and HPLC-DAD for the Investigation of Wine-Making By-Products. Molecules 2019, 24, 3416, doi:10.3390/molecules24193416.

29.

Tacchini, M.; Burlini, I.; Maresca, I.; Grandini, A.; Bernardi, T.; Guerrini, A.; Lerin, L.; Sacchetti, G. Polyphenols From Vitis Vinifera Lambrusco By-Products (Leaves From Pruning): Extraction Parameters Evaluation Through Design of Experiment. Natural Product Communications 2019, 14, 1934578X1986290, doi:10.1177/1934578X19862906.

30.

Radice, M.; Pietrantoni, A.; Guerrini, A.; Tacchini, M.; Sacchetti, G.; Chiurato, M.; Venturi, G.; Fortuna, C. Inhibitory Effect of Ocotea Quixos (Lam.) Kosterm. and Piper Aduncum L. Essential Oils from Ecuador on West Nile Virus Infection. Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 2019, 153, 344–351, doi:10.1080/11263504.2018.1478902.

31.

Giovannini, P.P.; Catani, M.; Massi, A.; Sacchetti, G.; Tacchini, M.; Oliveira, D.; Lerin, L.A. Continuous Production of Eugenol Esters Using Enzymatic Packed‐bed Microreactors and an Evaluation of the Products as Antifungal Agents. Flavour Fragr J 2019, 34, 201–210, doi:10.1002/ffj.3492.

32.

Ballesteros, J.L.; Tacchini, M.; Spagnoletti, A.; Grandini, A.; Paganetto, G.; Neri, L.M.; Marengo, A.; Angiolella, L.; Guerrini, A.; Sacchetti, G. Rediscovering Medicinal Amazonian Aromatic Plants: Piper Carpunya (Piperaceae) Essential Oil as Paradigmatic Study. Evidence-Based Complementary and Alternative Medicine 2019, 2019, 1–10, doi:10.1155/2019/6194640.

33.

Scalvenzi, L.; Radice, M.; Toma, L.; Severini, F.; Boccolini, D.; Bella, A.; Guerrini, A.; Tacchini, M.; Sacchetti, G.; Chiurato, M.; et al. Larvicidal Activity of Ocimum Campechianum , Ocotea Quixos and Piper Aduncum Essential Oils against Aedes Aegypti. Parasite 2019, 26, 23, doi:10.1051/parasite/2019024.

34.

Vinueza, D.; Yanza, K.; Tacchini, M.; Grandini, A.; Sacchetti, G.; Chiurato, M.A.; Guerrini, A. Flavonoids in Ecuadorian Oreocallis Grandiflora (Lam.) R. Br.: Perspectives of Use of This Species as a Food Supplement. Evidence-Based Complementary and Alternative Medicine 2018, 2018, 1–9, doi:10.1155/2018/1353129.

35.

Chiocchio, I.; Mandrone, M.; Sanna, C.; Maxia, A.; Tacchini, M.; Poli, F. Screening of a Hundred Plant Extracts as Tyrosinase and Elastase Inhibitors, Two Enzymatic Targets of Cosmetic Interest. Industrial Crops and Products 2018, 122, 498–505, doi:10.1016/j.indcrop.2018.06.029.

36.

Saab, A.M.; Gambari, R.; Sacchetti, G.; Guerrini, A.; Lampronti, I.; Tacchini, M.; El Samrani, A.; Medawar, S.; Makhlouf, H.; Tannoury, M.; et al. Phytochemical and Pharmacological Properties of Essential Oils from Cedrus Species. Natural Product Research 2018, 32, 1415–1427, doi:10.1080/14786419.2017.1346648.

37.

Turrini, E.; Catanzaro, E.; Muraro, M.G.; Governa, V.; Trella, E.; Mele, V.; Calcabrini, C.; Morroni, F.; Sita, G.; Hrelia, P.; et al. Hemidesmus Indicus Induces Immunogenic Death in Human Colorectal Cancer Cells. Oncotarget 2018, 9, 24443–24456, doi:10.18632/oncotarget.25325.

38.

Turrini, E.; Calcabrini, C.; Tacchini, M.; Efferth, T.; Sacchetti, G.; Guerrini, A.; Paganetto, G.; Catanzaro, E.; Greco, G.; Fimognari, C. In Vitro Study of the Cytotoxic, Cytostatic, and Antigenotoxic Profile of Hemidesmus Indicus (L.) R.Br. (Apocynaceae) Crude Drug Extract on T Lymphoblastic Cells. Toxins 2018, 10, 70, doi:10.3390/toxins10020070.

39.

Tacchini, M.; Spagnoletti, A.; Brighenti, V.; Prencipe, F.P.; Benvenuti, S.; Sacchetti, G.; Pellati, F. A New Method Based on Supercritical Fluid Extraction for Polyacetylenes and Polyenes from Echinacea Pallida (Nutt.) Nutt. Roots. Journal of Pharmaceutical and Biomedical Analysis 2017, 146, 1–6, doi:10.1016/j.jpba.2017.07.053.

40.

Tommasi, E.; Cravotto, G.; Galletti, P.; Grillo, G.; Mazzotti, M.; Sacchetti, G.; Samorì, C.; Tabasso, S.; Tacchini, M.; Tagliavini, E. Enhanced and Selective Lipid Extraction from the Microalga P. Tricornutum by Dimethyl Carbonate and Supercritical CO ₂ Using Deep Eutectic Solvents and Microwaves as Pretreatment. ACS Sustainable Chem. Eng. 2017, 5, 8316–8322, doi:10.1021/acssuschemeng.7b02074.

41.

Gresta, F.; Guerrini, A.; Sacchetti, G.; Tacchini, M.; Sortino, O.; Ceravolo, G.; Onofri, A. Agronomic, Chemical, and Antioxidant Characterization of Grain Amaranths Grown in a Mediterranean Environment. Crop Science 2017, 57, 2688–2698, doi:10.2135/cropsci2016.06.0531.

42.

Esposito, F.; Mandrone, M.; Del Vecchio, C.; Carli, I.; Distinto, S.; Corona, A.; Lianza, M.; Piano, D.; Tacchini, M.; Maccioni, E.; et al. Multi-Target Activity of Hemidesmus Indicus Decoction against Innovative HIV-1 Drug Targets and Characterization of Lupeol Mode of Action. Pathogens and Disease 2017, 75, doi:10.1093/femspd/ftx065.

43.

Massi, A.; Bortolini, O.; Ragno, D.; Bernardi, T.; Sacchetti, G.; Tacchini, M.; De Risi, C. Research Progress in the Modification of Quercetin Leading to Anticancer Agents. Molecules 2017, 22, 1270, doi:10.3390/molecules22081270.

44.

Scalvenzi, L.; Grandini, A.; Spagnoletti, A.; Tacchini, M.; Neill, D.; Ballesteros, J.; Sacchetti, G.; Guerrini, A. Myrcia Splendens (Sw.) DC. (Syn. M. Fallax (Rich.) DC.) (Myrtaceae) Essential Oil from Amazonian Ecuador: A Chemical Characterization and Bioactivity Profile. Molecules 2017, 22, 1163, doi:10.3390/molecules22071163.

45.

Lampronti, I.; Dechecchi, M.C.; Rimessi, A.; Bezzerri, V.; Nicolis, E.; Guerrini, A.; Tacchini, M.; Tamanini, A.; Munari, S.; D’Aversa, E.; et al. β-Sitosterol Reduces the Expression of Chemotactic Cytokine Genes in Cystic Fibrosis Bronchial Epithelial Cells. Front. Pharmacol. 2017, 8, 236, doi:10.3389/fphar.2017.00236.

46.

Tacchini, M.; Paganetto, G.; Efferth, T.; Sacchetti, G.; Guerrini, A. Chemical Characterisation and Cytotoxicity Evaluation of Convolvulus Pluricaulis Sieb. Ex Spreng. (Convolvulaceae) Extracts towards Sensitive and Multidrug-Resistant Cancer Cells. Planta Med 2016, 81, S1–S381, doi:10.1055/s-0036-1596484.

47.

Nostro, A.; Guerrini, A.; Marino, A.; Tacchini, M.; Di Giulio, M.; Grandini, A.; Akin, M.; Cellini, L.; Bisignano, G.; Saraçoğlu, H.T. In Vitro Activity of Plant Extracts against Biofilm-Producing Food-Related Bacteria. International Journal of Food Microbiology 2016, 238, 33–39, doi:10.1016/j.ijfoodmicro.2016.08.024.

48.

Spagnoletti, A.; Guerrini, A.; Tacchini, M.; Vinciguerra, V.; Leone, C.; Maresca, I.; Simonetti, G.; Sacchetti, G.; Angiolella, L. Chemical Composition and Bio-Efficacy of Essential Oils from Italian Aromatic Plants: Mentha Suaveolens, Coridothymus Capitatus, Origanum Hirtum and Rosmarinus Officinalis. Natural Product Communications 2016, 11, 1934578X1601101, doi:10.1177/1934578X1601101023.

49.

Turrini, E.; Calcabrini, C.; Sestili, P.; Catanzaro, E.; de Gianni, E.; Diaz, A.; Hrelia, P.; Tacchini, M.; Guerrini, A.; Canonico, B.; et al. Withania Somnifera Induces Cytotoxic and Cytostatic Effects on Human T Leukemia Cells. Toxins 2016, 8, 147, doi:10.3390/toxins8050147.

50.

Tacchini, M.; Spagnoletti, A.; Marieschi, M.; Caligiani, A.; Bruni, R.; Efferth, T.; Sacchetti, G.; Guerrini, A. Phytochemical Profile and Bioactivity of Traditional Ayurvedic Decoctions and Hydro-Alcoholic Macerations of Boerhaavia Diffusa L. and Curculigo Orchioides Gaertn. Natural Product Research 2015, 29, 2071–2079, doi:10.1080/14786419.2014.1003299.

51.

Statti, G.; Marrelli, M.; Conforti, F.; Spagnoletti, A.; Tacchini, M.; Fimognari, C.; Brognara, E.; Gambari, R.; Sacchetti, G.; Guerrini, A. Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus Indicus R. Br.: Biological Activity of Hemidesmus Indicus R. Br. Phytother. Res. 2015, 29, 857–863, doi:10.1002/ptr.5322.

52.

Turrini, E.; Ferruzzi, L.; Guerrini, A.; Gotti, R.; Tacchini, M.; Teti, G.; Falconi, M.; Hrelia, P.; Fimognari, C. In Vitro Anti-Angiogenic Effects of Hemidesmus Indicus in Hypoxic and Normoxic Conditions. Journal of Ethnopharmacology 2015, 162, 261–269, doi:10.1016/j.jep.2014.12.010.

53.

A. Guerrini; D. Rossi; A. Grandini; L. Scalvenzi; P.F. Noriega Rivera; E. Andreotti; M. Tacchini; A. Spagnoletti; I. Poppi; S. Maietti; et al. Biological and Chemo-Diverse Characterization of Amazonian (Ecuador) Citrus Petitgrains. Journal of Applied Botany and Food Quality; 87; 108-116 2014, doi:10.5073/JABFQ.2014.087.017.

54.

Rossi, D.; Guerrini, A.; Paganetto, G.; Bernacchia, G.; Conforti, F.; Statti, G.; Maietti, S.; Poppi, I.; Tacchini, M.; Sacchetti, G. Croton Lechleri Müll. Arg. (Euphorbiaceae) Stem Bark Essential Oil as Possible Mutagen-Protective Food Ingredient against Heterocyclic Amines from Cooked Food. Food Chemistry 2013, 139, 439–447, doi:10.1016/j.foodchem.2013.01.076.

55.

Ferruzzi, L.; Turrini, E.; Burattini, S.; Falcieri, E.; Poli, F.; Mandrone, M.; Sacchetti, G.; Tacchini, M.; Guerrini, A.; Gotti, R.; et al. Hemidesmus Indicus Induces Apoptosis as Well as Differentiation in a Human Promyelocytic Leukemic Cell Line. Journal of Ethnopharmacology 2013, 147, 84–91, doi:10.1016/j.jep.2013.02.009.