Pubblicazioni

  1. Casciano F, Caruso L, Zauli E, Gonelli A, Zauli G, Vaccarezza M. Emerging Mechanisms of Physical Exercise Benefits in Adjuvant and Neoadjuvant Cancer Immunotherapy. Biomedicines. 2024; 12(11):2528. https://doi.org/10.3390/biomedicines12112528
  2. Romani A, Lodi G, Casciano F, Gonelli A, Secchiero P, Zauli G, Bortolini O, Valacchi G, Ragno D, Bondi A, Benedusi M, Esposito E, Voltan R. Enhanced Anti-Melanoma Activity of Nutlin-3a Delivered via Ethosomes: Targeting p53-Mediated Apoptosis in HT144 Cells. Cells. 2024; 13(20):1678. https://doi.org/10.3390/cells13201678
  3. Marchesi E, Melloni E, Casciano F, Pozza E, Argazzi R, De Risi C, Preti L, Perrone D, Navacchia ML. Evaluation of Anticancer Activity of Nucleoside–Nitric Oxide Photo-Donor Hybrids. Molecules. 2024; 29(14):3383. https://doi.org/10.3390/molecules29143383
  4. Esposito E, Pozza E, Contado C, Pula W, Bortolini O, Ragno D, Toldo S, Casciano F, Bondi A, Zauli E, Secchiero P, Zauli G, Melloni E. Microfluidic Fabricated Liposomes for Nutlin-3a Ocular Delivery as Potential Candidate for Proliferative Vitreoretinal Diseases Treatment. Int J Nanomedicine. 2024;19:3513-3536 https://doi.org/10.2147/IJN.S452134
  5. Casciano F†, Zauli E, Celeghini C, Caruso L, Gonelli A, Zauli G, Pignatelli A†. Retinal Alterations Predict Early Prodromal Signs of Neurodegenerative Disease. International Journal of Molecular Sciences. 2024, 25(3), 1689. https://doi.org/10.3390/ijms25031689
  6. Gentili V, Strazzabosco G, Salgari N, Mancini A, Rizzo S, Beltrami S, Schiuma G, Casciano F, Alogna A, Passarella D, Davinelli S, Scapagnini G, Medoro A, Rizzo R. Ozonated Oil in Liposome Eyedrops Reduces the Formation of Biofilm, Selection of Antibiotic-Resistant Bacteria, and Adhesion of Bacteria to Human Corneal Cells. International Journal of Molecular Sciences. 2023; 24(18):14078. https://doi.org/10.3390/ijms241814078
  7. Gentili V, Bortolotti D, Morandi L, Rizzo S, Schiuma G, Beltrami S, Casciano F, Papi A, Contoli M, Zauli G, Rizzo R. Natural Killer Cells in SARS-CoV-2-Vaccinated Subjects with Increased Effector Cytotoxic CD56dim Cells and Memory-Like CD57+NKG2C+CD56dim Cells. Front Biosci (Landmark Ed). 2023;28(7):156. https://doi.org/10.31083/j.fbl2807156
  8. Casciano F†, Zauli E, Busin M, Caruso L, AlMesfer S, Al-Swailem S, Zauli G, Yu AC. State of the Art of Pharmacological Activators of p53 in Ocular Malignancies. Cancers. 2023; 15(14):3593. https://doi.org/10.3390/cancers15143593
  9. Manera M, Casciano F, Giari L. Ultrastructural Alterations of the Glomerular Filtration Barrier in Fish Experimentally Exposed to Perfluorooctanoic Acid. Int J Environ Res Public Health. 2023; 20(7):5253. https://doi.org/10.3390/ijerph20075253.
  10. Casciano F, Bianchi N, Borin M, Vellani V, Secchiero P, Bergamini CM, Capsoni S, Pignatelli A. Characterization by Gene Expression Analysis of Two Groups of Dopaminergic Cells Isolated from the Mouse Olfactory Bulb. Biology. 2023;12(3):367. https://doi.org/10.3390/biology12030367.
  11. Montico G*, Mingozzi F*, Casciano F*, Protti G, Gornati L, Marzola E, Banfi G, Guerrini R, Secchiero P, Volinia S, Granucci F, Reali E. CCR4+CD8+ T cells clonally expand to differentiated effectors in murine psoriasis and in human psoriatic arthritis. Eur J Immunol. 2023;Feb 1:e2149702. https://doi.org/10.1002/eji.202149702.
  12. Feriotto G, Marchetti P, Rondanin R, Tagliati F, Aguzzi S, Beninati S, Casciano F, Tabolacci C, Mischiati C. Cytotoxicity of Isoxazole Curcumin Analogs on Chronic Myeloid Leukemia-Derived K562 Cell Lines Sensitive and Resistant to Imatinib. Int J Mol Sci. 2023;24(3):2356. https://doi.org/10.3390/ijms22041644.
  13. Lodi G*, Gentili V*, Casciano F*, Romani A, Zauli G, Secchiero P, Zauli E, Simioni C, Beltrami S, Fernandez M, Rizzo R, Voltan R. Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells. Front Pharmacol. 2022;13. https://doi.org/10.3389/fphar.2022.1018761.
  14. Sergi D, Zauli E, Casciano F†, Secchiero P, Zauli G, Fields M, Melloni E. Palmitic Acid Induced a Long-Lasting Lipotoxic Insult in Human Retinal Pigment Epithelial Cells, which Is Partially Counteracted by TRAIL. Antioxidants. 2022;11(12):2340. https://doi.org/10.3390/antiox11122340.
  15. Casciano F†, Zauli E, Rimondi E, Mura M, Previati M, Busin M, Zauli G. The role of the mTOR pathway in diabetic retinopathy. Front Med. 2022;9:1-16. https://doi.org/10.3389/fmed.2022.973.
  16. Melloni E, Marchesi E, Preti L, Casciano F, Rimondi E, Romani A, Secchiero P, Navacchia ML, Perrone D. Synthesis and Biological Investigation of Bile Acid-Paclitaxel Hybrids. Molecules. 2022;27(2):471. https://doi.org/10.3390/molecules27020471.
  17. Romani A*, Casciano F*, Stevanin C, Maietti A, Tedeschi P, Secchiero P, Marchetti N, Voltan R. Anticancer activity of aqueous extracts from asparagus officinalis l. Byproduct on breast cancer cells. Molecules. 2021;26(21). https://doi.org/10.3390/molecules26216369.
  18. Capsoni S, Iseppe AF, Casciano F, Pignatelli A. Unraveling the Role of Dopaminergic and Calretinin Interneurons in the Olfactory Bulb. Front Neural Circuits. 2021; 15:718221. https://doi.org/10.3389/fncir.2021.718221.
  19. Ferrari D*, Casciano F*, Secchiero P, Reali E. Purinergic Signaling and Inflammasome Activation in Psoriasis Pathogenesis. Int J Mol Sci. 2021; 22(17), 9449. https://doi.org/10.3390/ijms22179449.
  20. Rimondi E, Melloni E, Romani A, Tisato V, Casciano F, Rigolin GM, Milani D, Celeghini C, Zauli G, Secchiero P, Voltan R. Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors. Curr Oncol. 2021; 28(4), 2439-2451. https://doi.org/10.3390/curroncol28040223.
  21. Ferrari D†, la Sala A, Milani D, Celeghini C, Casciano F†. Purinergic Signaling in Controlling Macrophage and T Cell Functions During Atherosclerosis Development. Front Immunol. 2021; 11:617804. https://doi.org/10.3389/fimmu.2020.617804.
  22. Feriotto G, Tagliati F, Giriolo R, Casciano F, Tabolacci C, Beninati S, Khan MTH, Mischiati C. Caffeic Acid Enhances the Anti-Leukemic Effect of Imatinib on Chronic Myeloid Leukemia Cells and Triggers Apoptosis in Cells Sensitive and Resistant to Imatinib. Int J Mol Sci. 2021; 6;22(4):1644. https://10.3390/ijms22041644.
  23. Bortoluzzi A, Chighizola CB, Fredi M, Raschi E, Bodio C, Privitera D, Gonelli A, Silvagni E, Govoni M, Cavazzana I, Airò P, Meroni PL, Tincani A, Franceschini F, Piantoni S, Casciano F. The IMMENSE Study: The Interplay Between iMMune and ENdothelial Cells in Mediating Cardiovascular Risk in Systemic Lupus Erythematosus. Front Immunol. 2020; 11:572876. https://doi.org/10.3389/fimmu.2020.572876.
  24. Rimondi E, Marcuzzi A, Casciano F, Tornese G, Pellati A,Toffoli B, Secchiero P, Melloni E. Role of vitamin D in the pathogenesis of atheromatosis. Nutr Metab Cardiovasc Dis. 2020; 31(1): 344–353. https://doi.org/10.1016/j.numecd.2020.08.031.
  25. Ferrari D†, Vuerich M, Casciano F†, Longhi MS, Melloni E, Secchiero P, Zech A, Robson SC, Muller T, Idzko M. Eosinophils and Purinergic Signaling in Health and Disease. Front Immunol. 2020;11:1339. https://doi.org/10.3389/fimmu.2020.01339.
  26. Casciano F, Diani M, Altomare A, Granucci F, Secchiero P, Banfi G, Reali E. CCR4(+) Skin-Tropic Phenotype as a Feature of Central Memory CD8(+) T Cells in Healthy Subjects and Psoriasis Patients. Front Immunol. 2020;11:529. https://doi.org/10.3389/fimmu.2020.00529.
  27. Diani M*, Casciano F*, Marongiu L*, Longhi M, Altomare A, Pigatto PD, Secchiero P, Gambari R, Banfi G, Manfredi AA, Altomare G, Granucci F, Reali E. Increased frequency of activated CD8+ T cell effectors in patients with psoriatic arthritis. Sci Rep. 2019;9(1):10870. https://doi.org/10.1038/s41598-019-47310-5.
  28. Trapella C, Rizzo R, Gallo S, Alogna A, Bortolotti D, Casciano F, Zauli G, Secchiero P, Voltan R. HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts. Sci Rep. 2018;8(1):17665. https://doi.org/10.1038/s41598-018-35816-3.
  29. Chiriaco M, Casciano F, Di Matteo G, Gentner B, Claps A, Di Cesare S, Cotugno N, D'Argenio P, Rossi P, Aiuti A, Finocchi A. Impaired X-CGD T cell compartment is gp91phox-NADPH oxidase independent. Clin Immunol. 2018;193:52-59. https://doi.org/10.1016/j.clim.2018.01.010.
  30. Casciano F, Pigatto PD, Secchiero P, Gambari R, Reali E. T Cell Hierarchy in the Pathogenesis of Psoriasis and Associated Cardiovascular Comorbidities. Front Immunol. 2018;9(1390):1390. https://doi.org/10.3389/fimmu.2018.01390.
  31. Feriotto G, Calza R, Bergamini CM, Griffin M, Wang Z, Beninati S, Ferretti V, Marzola E, Guerrini R, Pagnoni A, Cavazzini A, Casciano F, Mischiati C. Involvement of cell surface TG2 in the aggregation of K562 cells triggered by gluten. Amino Acids. 2017;49(3):551-565. https://doi.org/10.1007/s00726-016-2339-4.
  32. D'Abundo L, Callegari E, Bresin A, Chillemi A, Elamin BK, Guerriero P, Huang X, Saccenti E, Hussein E, Casciano F, Secchiero P, Zauli G, Calin GA, Russo G, Lee LJ, Croce CM, Marcucci G, Sabbioni S, Malavasi F, Negrini M. Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model. Oncogene. 2017;36(47):6617-6626. https://doi.org/10.1038/onc.2017.269.
  33. Voltan R, Secchiero P, Casciano F, Milani D, Zauli G, Tisato V. Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity. Int J Biochem Cell Biol. 2016;81(Pt B):364-374. https://doi.org/10.1016/j.biocel.2016.09.019.
  34. Voltan R, Rimondi E, Melloni E, Rigolin GM, Casciano F, Arcidiacono MV, Celeghini C, Cuneo A, Zauli G, Secchiero P. Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia. Oncotarget. 2016;7(43):70623-70638. https://doi.org/10.18632/oncotarget.12139.
  35. Voltan R, Rimondi E, Melloni E, Gilli P, Bertolasi V, Casciano F, Rigolin GM, Zauli G, Secchiero P. Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1. Oncotarget. 2016;7(14):18965-18977. https://doi.org/10.18632/oncotarget.7879.
  36. Agnoletto C, Brunelli L, Melloni E, Pastorelli R, Casciano F, Rimondi E, Rigolin GM, Cuneo A, Secchiero P, Zauli G. The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget. 2015;6(4):2385-2396. https://doi.org/10.18632/oncotarget.2960.
  37. Tisato V, Garrovo C, Biffi S, Petrera F, Voltan R, Casciano F, Meroni G, Agnoletto C, Zauli G, Secchiero P. Intranasal administration of recombinant TRAIL down-regulates CXCL-1/KC in an ovalbumin-induced airway inflammation murine model. PLoS One. 2014;9(12):e115387. https://doi.org/10.1371/journal.pone.0115387.
  38. Cianci R, Frosali S, Pagliari D, Cesaro P, Petruzziello L, Casciano F, Landolfi R, Costamagna G, Pandolfi F. Uncomplicated diverticular disease: innate and adaptive immunity in human gut mucosa before and after rifaximin. J Immunol Res. 2014;2014:696812. https://doi.org/10.1155/2014/696812.
  39. Agnoletto C, Melloni E, Casciano F, Rigolin GM, Rimondi E, Celeghini C, Brunelli L, Cuneo A, Secchiero P, Zauli G. Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3. Oncotarget. 2014;5(12):4347-4360. https://doi.org/10.18632/oncotarget.2018.
  40. Tisato V, Secchiero P, Rimondi E, Gianesini S, Menegatti E, Casciano F, Zamboni P, Zauli G. GM-CSF exhibits anti-inflammatory activity on endothelial cells derived from chronic venous disease patients. Mediators Inflamm. 2013;2013:561689. https://doi.org/10.1155/2013/561689.
  41. Rampazzo E, Voltan R, Petrizza L, Zaccheroni N, Prodi L, Casciano F, Zauli G, Secchiero P. Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis. Nanoscale. 2013;5(17):7897-7905. https://doi.org/10.1039/c3nr02563b.
  42. Cianci R, Cammarota G, Frisullo G, Pagliari D, Ianiro G, Martini M, Frosali S, Plantone D, Damato V, Casciano F, Landolfi R, Paola Batocchi A, Pandolfi F. Tissue-infiltrating lymphocytes analysis reveals large modifications of the duodenal "immunological niche" in coeliac disease after gluten-free diet. Clin Transl Gastroenterol. 2012;3:e28. https://doi.org/10.1038/ctg.2012.22.
  43. Pandolfi F, Cianci R, Pagliari D, Casciano F, Bagala C, Astone A, Landolfi R, Barone C. The immune response to tumors as a tool toward immunotherapy. Clin Dev Immunol. 2011;2011:894704. https://doi.org/10.1155/2011/894704.
  44. Pandolfi F, Cianci R, Casciano F, Pagliari D, De Pasquale T, Landolfi R, Di Sante G, Kurnick JT, Ria F. Skewed T-cell receptor repertoire: more than a marker of malignancy, a tool to dissect the immunopathology of inflammatory diseases. J Biol Regul Homeost Agents. 2011;25(2):153-161.
  45. Cianci R, Casciano F, Costamagna G, Pandolfi F. Comment on: Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in vitro approach using a continuous culture colonic model system. J Antimicrob Chemother. 2011;66(5):1193-1194; author reply 1194-1195. https://doi.org/10.1093/jac/dkr031.

 

† Corresponding Author

*These authors have contributed equally to this work