Pubblicazioni
- Sergi D.;, Zauli E.;, Celeghini C.;Previati M.; Zauli G. Ceramides as the molecular link between impaired lipid metabolism, saturated fatty acid intake and insulin resistance: are all saturated fatty acids to be blamed for ceramide-mediated lipotoxicity? Articolo accettato per la pubblicazione su Nutrition Research Reviews ISSN: 0954-4224 (Print), 1475-2700 (Online).
- Spaggiari, R.; Angelini, S.; Di Vincenzo, A.; Scaglione, G.; Morrone, S.; Finello, V.; Fagioli, S.; Castaldo, F.; Sanz, J.M.; Sergi, D#.; Passaro, A. Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet. Adv Nutr 2024, 15, 100252, doi:10.1016/j.advnut.2024.100252.
- Sergi, D.; Sanz, J.M.; Trentini, A.; Bonaccorsi, G.; Angelini, S.; Castaldo, F.; Morrone, S.; Spaggiari, R.; Cervellati, C.; Passaro, A., et al. HDL-Cholesterol Subfraction Dimensional Distribution Is Associated with Cardiovascular Disease Risk and Is Predicted by Visceral Adiposity and Dietary Lipid Intake in Women. Nutrients 2024, 16, doi:10.3390/nu16101525.
- Passaro, A.; Sanz, J.M.; Naumovski, N.; Sergi, D. The complex interplay between oxinflammation, mitochondrial dysfunction and lipotoxicity: focus on their role in the pathogenesis of skeletal muscle insulin resistance and modulation by dietary fatty acids. Advances in Redox Research 2024, 100100.
- Kouvari, M.; Sergi, D.; Zec, M.; Naumovski, N. Editorial: Nutrition in Prevention and Management of Non-alcoholic Fatty Liver Disease. Frontiers in Nutrition 10, 1212363.
- Sanz, J.M.; D'Amuri, A.; Sergi, D.; Angelini, S.; Fortunato, V.; Favari, E.; Vigna, G.; Zuliani, G.; Dalla Nora, E.; Passaro, A. Cholesterol efflux capacity is increased in subjects with familial hypercholesterolemia in a retrospective case-control study. Sci Rep 2023, 13, 8415, doi:10.1038/s41598-023-35357-4.
- Sergi, D.; Sanz, J.M.; Lazzer, S.; Brombo, G.; Zuliani, G.; Biolo, G.; Simunic, B.; Pisot, R.; Dalla Nora, E.; Passaro, A. Interleukin-18 Is a Potential Biomarker Linking Dietary Fatty Acid Quality and Insulin Resistance: Results from a Cross-Sectional Study in Northern Italy. Nutrients 2023, 15, doi:10.3390/nu15071782.
- Melloni, M.; Sergi, D. #; Simioni, C.; Passaro, A.; Neri, L.M. Microalgae as a Nutraceutical Tool to Antagonize the Impairment of Redox Status Induced by SNPs: Implications on Insulin Resistance. Biology (Basel) 2023, 12, doi:10.3390/biology12030449.
- Sergi, D.; Zauli, E.; Tisato, V.; Secchiero, P.; Zauli, G.; Cervellati, C. Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The Impact of HDL-Cholesterol and Ceramides. Int J Mol Sci 2023, 24, doi:10.3390/ijms24054403.
10. Kouvari, M.; D'Cunha N.M..; Tsiampalis, T.; Zec, M.; Sergi, D.; Travica, N.; Marx, W.; McKune, A.J.; Panagiotakos, D.B.; Naumovski, N. Metabolically Healthy Overweight and Obesity, Transition to Metabolically Unhealthy Status and Cognitive Function: Results from the Framingham Offspring Study. Nutrients 2023, 15, doi:10.3390/nu15051289.
11. Romani, A.; Sergi, D. #; Zauli, E.; Voltan, R.; Lodi, G.; Vaccarezza, M.; Caruso, L.; Previati, M.; Zauli, G. Nutrients, herbal bioactive derivatives and commensal microbiota as tools to lower the risk of SARS-CoV-2 infection. Front Nutr 2023, 10, 1152254, doi:10.3389/fnut.2023.1152254.
12. Bordoni, L.; Zec, M.; Naumovski, N.; Sergi, D. Editorial: The role of dietary fatty acids in metabolic health. Front Physiol 2023, 14, 1211151, doi:10.3389/fphys.2023.1211151.
13. Sergi, D.; Zauli, E.; Casciano, F.; Secchiero, P.; Zauli, G.; Fields, M.; Melloni, E. Palmitic Acid Induced a Long-Lasting Lipotoxic Insult in Human Retinal Pigment Epithelial Cells, which Is Partially Counteracted by TRAIL. Antioxidants (Basel) 2022, 11, doi:10.3390/antiox11122340.
14. Cervellati, C.; Sergi, D.; Loria-Kohen, V.; Trentini, A. Editorial: Endogenous and exogenous factors influencing the function and metabolism of lipoproteins. Front Mol Biosci 2022, 9, 1097963, doi:10.3389/fmolb.2022.1097963.
15. Fisette, A.; Sergi, D.#; Breton-Morin, A.; Descoteaux, S.; Martinoli, M.G. New Insights on the Role of Bioactive Food Derivatives in Neurodegeneration and Neuroprotection. Curr Pharm Des 2022, 28, 3068-3081, doi:10.2174/1381612828666220919085742.
16. Suriano, F.; Nystrom, E.E.L.; Sergi, D.; Gustafsson, J.K. Diet, microbiota, and the mucus layer: The guardians of our health. Front Immunol 2022, 13, 953196, doi:10.3389/fimmu.2022.953196.
17. Sergi, D.; Bordoni, L. Editorial: Molecular nutrition as preventive tool in non-communicable diseases: Mechanistic insights and risk biomarkers. Front Nutr 2022, 9, 1005397, doi:10.3389/fnut.2022.1005397.
18. Kouvari, M.; Sergi, D.; D’Cunha, N.M.; Bulman, A.; Panagiotakos, D.B.; Naumovski, N. Is Non-Alcoholic Fatty Liver Disease Connected with Cognition? The Complex Interplay between Liver and Brain. Diabetology 2022, 3, 355-363.
19. D'Cunha, N.M.; Sergi, D.; Lane, M.M.; Naumovski, N.; Gamage, E.; Rajendran, A.; Kouvari, M.; Gauci, S.; Dissanayka, T.; Marx, W., et al. The Effects of Dietary Advanced Glycation End-Products on Neurocognitive and Mental Disorders. Nutrients 2022, 14, doi:10.3390/nu14122421.
20. Sanz, J.M.; Sergi, D.; Colombari, S.; Capatti, E.; Situlin, R.; Biolo, G.; Di Girolamo, F.G.; Lazzer, S.; Simunic, B.; Pisot, R., et al. Dietary Acid Load but Not Mediterranean Diet Adherence Score Is Associated With Metabolic and Cardiovascular Health State: A Population Observational Study From Northern Italy. Front Nutr 2022, 9, 828587, doi:10.3389/fnut.2022.828587.
21. Kashif, R.R.; D'Cunha, N.M.; Mellor, D.D.; Alexopoulos, N.I.; Sergi, D.; Naumovski, N. Prickly Pear Cacti (Opuntia spp.) Cladodes as a Functional Ingredient for Hyperglycemia Management: A Brief Narrative Review. Medicina (Kaunas) 2022, 58, doi:10.3390/medicina58020300.
22. Bochenek, H.; Krga, I.; Sergi, D.; Kouvari, M.; Zec, M.; Naumovski, N. Dietary patterns, caloric restrictions for management of cardiovascular disease and cancer; a brief review. Rev Cardiovasc Med 2022, 23, 41, doi:10.31083/j.rcm2301041.
23. Kouvari, M.; D'Cunha, N.M.; Travica, N.; Sergi, D.; Zec, M.; Marx, W.; Naumovski, N. Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review. Nutrients 2022, 14, doi:10.3390/nu14020333.
24. Beaulieu J, Costa G, Renaud J, Moitie A, Glemet H, Sergi D, Martinoli MG (2021) The Neuroinflammatory and Neurotoxic Potential of Palmitic Acid Is Mitigated by Oleic Acid in Microglial Cells and Microglial-Neuronal Co-cultures. Mol Neurobiol 58 (6):3000-3014. doi:10.1007/s12035-021-02328-7
25. Sergi D, Luscombe-Marsh N, Naumovski N, Abeywardena M, O'Callaghan N (2021) Palmitic Acid, but Not Lauric Acid, Induces Metabolic Inflammation, Mitochondrial Fragmentation, and a Drop in Mitochondrial Membrane Potential in Human Primary Myotubes. Front Nutr 8:663838. doi:10.3389/fnut.2021.663838
26. Sergi D, Gelinas A, Beaulieu J, Renaud J, Tardif-Pellerin E, Guillard J, Martinoli MG (2021) Anti-Apoptotic and Anti-Inflammatory Role of Trans epsilon-Viniferin in a Neuron-Glia Co-Culture Cellular Model of Parkinson's Disease. Foods 10 (3). doi:10.3390/foods10030586
27. Stonehouse W, Sergi D, Benassi-Evans B, James-Martin G, Johnson N, Thompson CH, Abeywardena M (2021) Eucaloric diets enriched in palm olein, cocoa butter, and soybean oil did not differentially affect liver fat concentration in healthy participants: a 16-week randomized controlled trial. Am J Clin Nutr 113 (2):324-337. doi:10.1093/ajcn/nqaa347
28. Sergi D, Luscombe-Marsh N, Heilbronn LK, Birch-Machin M, Naumovski N, Lionetti L, Proud CG, Abeywardena MY, O'Callaghan N (2021) The Inhibition of Metabolic Inflammation by EPA Is Associated with Enhanced Mitochondrial Fusion and Insulin Signaling in Human Primary Myotubes. J Nutr. doi:10.1093/jn/nxaa430
29. Naumovski N, Sergi D (2021) Food Bioactives: Impact on Brain and Cardiometabolic Health-Findings from In Vitro to Human Studies. Foods 10 (5). doi:10.3390/foods10051045
30. Sergi D, Boulestin H, Campbell FM, Williams LM (2021) The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction. Mol Nutr Food Res 65 (1):e1900934. doi:10.1002/mnfr.201900934
31. Sergi D, Morris AC, Kahn DE, McLean FH, Hay EA, Kubitz P, MacKenzie A, Martinoli MG, Drew JE, Williams LM (2018) Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4. Nutritional neuroscience:1-14. doi:10.1080/1028415X.2018.1501533
32. Sergi D, Williams LM (2020) Potential relationship between dietary long-chain saturated fatty acids and hypothalamic dysfunction in obesity. Nutr Rev 78 (4):261-277. doi:10.1093/nutrit/nuz056
33. Williams JL, Everett JM, D'Cunha NM, Sergi D, Georgousopoulou EN, Keegan RJ, McKune AJ, Mellor DD, Anstice N, Naumovski N (2019) The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review. Plant Foods Hum Nutr. doi:10.1007/s11130-019-00771-5
34. Williams J, McKune AJ, Georgousopoulou EN, Kellett J, D'Cunha NM, Sergi D, Mellor D, Naumovski N (2020) The Effect of L-Theanine Incorporated in a Functional Food Product (Mango Sorbet) on Physiological Responses in Healthy Males: A Pilot Randomised Controlled Trial. Foods 9 (3). doi:10.3390/foods9030371
35. McLean FH, Campbell FM, Sergi D, Grant C, Morris AC, Hay EA, MacKenzie A, Mayer CD, Langston RF, Williams LM (2019) Early and reversible changes to the hippocampal proteome in mice on a high-fat diet. Nutr Metab (Lond) 16:57. doi:10.1186/s12986-019-0387-y
36. Sergi D, Naumovski N, Heilbronn LK, Abeywardena M, O’Callaghan N, Lionetti L, Luscombe-Marsh N (2019) Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet. Frontiers in Physiology 10 (532). doi:10.3389/fphys.2019.00532
37. Munialo CD, Naumovski N, Sergi D, Stewart D, Mellor DD (2019) Critical evaluation of the extrapolation of data relative to antioxidant function from the laboratory and their implications on food production and human health: a review. International Journal of Food Science & Technology 54 (5):1448-1459
38. McLean FH, Campbell FM, Langston RF, Sergi D, Resch C, Grant C, Morris AC, Mayer CD, Williams LM (2019) A high-fat diet induces rapid changes in the mouse hypothalamic proteome. Nutrition & Metabolism 16 (1):26. doi:10.1186/s12986-019-0352-9
39. Williams J, Sergi D, McKune AJ, Georgousopoulou EN, Mellor DD, Naumovski N (2019) The beneficial health effects of green tea amino acid l-theanine in animal models: Promises and prospects for human trials. Phytotherapy research : PTR. doi:10.1002/ptr.6277
40. Sergi D, Renaud J, Simola N, Martinoli MG (2019) Diabetes, a Contemporary Risk for Parkinson's Disease: Epidemiological and Cellular Evidences. Front Aging Neurosci 11:302. doi:10.3389/fnagi.2019.00302
41. Speer H, D'Cunha NM, Botek M, McKune AJ, Sergi D, Georgousopoulou E, Mellor DD, Naumovski N (2019) The Effects of Dietary Polyphenols on Circulating Cardiovascular Disease Biomarkers and Iron Status: A Systematic Review. Nutr Metab Insights 12:1178638819882739. doi:10.1177/1178638819882739
42. Sergi D, Campbell FM, Grant C, Morris AC, Bachmair E-M, Koch C, McLean FH, Muller A, Hoggard N, de Roos B, Porteiro B, Boekschoten MV, McGillicuddy FC, Kahn D, Nicol P, Benzler J, Mayer C-D, Drew JE, Roche HM, Muller M, Nogueiras R, Dieguez C, Tups A, Williams LM (2018) SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice. Genes and Nutrition 13. doi:10.1186/s12263-018-0619-1
43. Tups A, Benzler J, Sergi D, Ladyman SR, Williams LM (2017) Central Regulation of Glucose Homeostasis. Comprehensive Physiology 7 (2):741-764. doi:10.1002/cphy.c160015
44. McGillicuddy FC, Reynolds CM, Finucane O, Coleman E, Harford KA, Grant C, Sergi D, Williams LM, Mills KH, Roche HM (2013) Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice. American journal of physiologyEndocrinology and metabolism 305 (7):E834-844. doi:10.1152/ajpendo.00297.2013
