Curriculum

Curriculum

FABRIZIO VINCENZI

PLACE AND DATE OF BIRTH: Modena (Italy), 07/12/1971

E-mail: fabrizio.vincenzi@unife.it

CURRENT POSITION: Associate Professor, academic discipline BIO/14 (Pharmacology), department of Translational Medicine, University of Ferrara.

 

 

QUALIFICATIONS

19/10/2004 - Degree in Biological Sciences

Thesis title: Alteration of A2A adenosine receptors in peripheral blood of Huntington's disease patients, carried out at the Pharmacology section, Department of Clinical and Experimental Medicine, University of Ferrara

02/03/2009 - PhD in Pharmacology and Molecular Oncology

Thesis title: Altered expression and functionality of A2A adenosine receptors in Huntington's disease and other polyglutamine disorders, carried out at the Pharmacology section, Department of Clinical and Experimental Medicine, University of Ferrara

19/11/2013 Expert in Pharmacology, Disciplinary Scientific Sector BIO / 14 - Competition Sector 05 / G1, for approval by the Council of the Department of Medical Sciences of the University of Ferrara.

Research activity

01/12/2004 - 31/01/2006 Coordinated and Continuous Collaboration Contract (co.co.co.) stipulated with the “Consorzio Futuro in Ricerca” for the carrying out of the project "Evaluation of the affinity and density of A2A adenosine receptors in blood cells of patients affected by polyglutamine neurological diseases "at the Pharmacology Section, Department of Clinical and Experimental Medicine, University of Ferrara.

01/01/2006 - 31/12/2008 PhD student at the Pharmacology section, Department of Clinical and Experimental Medicine, University of Ferrara.

01/02/2006 - 31/07/2006 winner of scholarship for research on the topic "Adenosine A3 receptors in subjects with colorectal neoplasms" funded by the Department of Anesthesiological and Radiological Surgical Sciences of the University of Ferrara and carried out at the Pharmacology Section, Department of Clinical and Experimental Medicine, University of Ferrara.

02/10/2006 - 01/10/2008 Research Fellow at the Pharmacology section, Department of Clinical and Experimental Medicine, University of Ferrara, within the project "Adenosine receptors as pathology biomarkers".

17/11/2008 - 21/01/2009 Coordinated and Continuous Collaboration Contract (co.co.co.) stipulated with the “Consorzio Futuro in Ricerca” for the development of the project "Adenosine receptors as pathology biomarkers" at the Section of Pharmacology, Department of Clinical and Experimental Medicine, University of Ferrara.

09/02/2009 - 21/04/2009 Coordinated and Continuous Collaboration Agreement (co.co.co.) stipulated with the “Consorzio Futuro in Ricerca” for the development of the project "Adenosine receptors as pathology biomarkers" at the Section of Pharmacology, Department of Clinical and Experimental Medicine, University of Ferrara.

23/04/2009 - 22/04/2010 Scholarship holder winner of the "SPINNER 2013 - Applied research projects, pre-competitive development, technology transfer" with project entitled "Electromagnetic fields in pathologies of the Central Nervous System", carried out at the Pharmacology section, Department of Clinical and Experimental Medicine, University of Ferrara.

01/05/2011 - 15/12/2011 Research Fellow at the Pharmacology section, Department of Clinical and Experimental Medicine, University of Ferrara, within the project "Study of the anti-inflammatory and analgesic activity of new allosteric modulators of the A1 adenosine receptor ".

16/12/2011 - 30/09/2018 Research Collaborator at the Pharmacology Section, Department of Medical Sciences, University of Ferrara.

01/10/2018 – Assistant Profesor, disciplinary scientific sector BIO / 14 (Pharmacology) at the Section of Pharmacology, Department of Medical Sciences, University of Ferrara.

PROJECT ACTIVITY REALIZATION

 

Owner of the project activity within the SPINNER 2013 program - Applied research projects, pre-competitive development and technology transfer. Project title: "Electromagnetic fields in central nervous system pathologies" (Project protocol number 259/08; duration: 12 months).

Participation in the PRIN 2008 project - Scientific coordinator Prof. Pier Andrea Borea (later replaced by Prof. Gaetano Caramori). Project title "Pharmacological and functional characterization of adenosine receptors in U937 cells and alveolar macrophages of patients with chronic obstructive pulmonary disease" (Project code 2008ESF8BW_001; duration 36 months).

 

PRIN 2017 – Scientific coordinator Prof. Marco Mor. Project title “Exploiting the EndoCannabinoid System to control inflammation and promote neuroprotection and myelin repair (ExECS)”.

 

FIR 2019 - “I recettori dell’adenosina come nuovo potenziale target terapeutico nell'ischemia cerebrale”, funded by University of Ferrara.

 

2021- Accordi di Innovazione "Fabbrica intelligente"- "Agrifood"- "Scienze della vita" – Project funded by the Italian Ministry of Economic Development (MISE). Project title: “Dispositivo Medico di Stimolazione Biofisica per la Rigenerazione della Cartilagine Articolare”.

 

Co-investigator in the following research projects entrusted by private entities:

 

2005-2009: IGEA SpA - project title: "New approaches for the study of the interaction between adenosine receptors and electromagnetic fields (CEMP) in the modulation of inflammatory processes at the articular level"

2010-2011: Nicox Research Institute - project title: "Nitric oxide (NO) -donating derivatives for the treatment of painful diabetic neuropathy"

2012: IGEA SpA - project title: "Low frequency pulsed electromagnetic fields enhance the anti-tumor effect of adenosine A3 receptors: in vitro and in vivo studies"

2012: IGEA SpA - project title: "Anti-inflammatory role of low frequency pulsed electromagnetic fields and A2A adenosine receptors in various cell lines such as osteoblasts and human chondrocytes"

2013-2017: Chiesi Farmaceutici SpA - project title: "Kinetic Analysis of ligands to M3 and M2 muscarinic receptors"

2014: IGEA SpA - project title: "New device for the treatment of post-traumatic spinal injuries using pulsed electromagnetic fields"

2015: IGEA SpA - title of the project: "Effect of pulsed electromagnetic field exposure in hypoxia and inflammation"

2016: IGEA SpA - project title: "Effect of pulsed electromagnetic field exposure in hypoxia and inflammation induced damage in microglial cells"

2017: IGEA SpA - project title: "Signaling pathways involved in the reduction of hypoxia and inflammation induced damage in microglial and neuron-like cells by pulsed electromagnetic field exposure"

2017: Phytoplant Research - project title: "Binding studies of phytocannabinoids at the cannabinoid receptors CB1 and CB2"

2018: IGEA SpA - title of the project: "In vitro effects of long-term chronic treatment of pulsed electromagnetic fields on metabolism and cell viability"

PATENT OWNERSHIP

 

Co-inventor of the patent filed on 07/07/2016 number 102016000070952 entitled "New thiazole [5,4-d] pyrimidin derivatives as inverse agonists of the A2A adenosine receptors" in partnership between the University of Ferrara and the University of Florence.