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**CURRENT POSITION:**
Associate Professor of Neurosurgery and Chief Medical Neurosurgeon at AOU Sant'Anna of Ferrara

**EDUCATIONAL QUALIFICATIONS**
- Degree in Medicine and Surgery from the Catholic University of the Sacred Heart of Rome
- Specialization in Neurosurgery from the Catholic University of the Sacred Heart of Rome
- Advanced specialization in Endovascular Neurointervention at La Sapienza University of Rome
- Research Fellowship in Skull Base Microsurgery (Ohio State University)
- Clinical Fellowship in Vascular Neurosurgery (Niguarda Hospital, Milan)

**TEACHING ACTIVITIES**
Lecturer of Neurosurgery in the following degree courses affiliated with Unife:
- Master's Degree in Medicine and Surgery
- School of Specialization in Neurosurgery

**MANAGEMENT ACTIVITIES**
- Member of the VQR commission, Unife
- Member of the Italian Society of Neurosurgery (SINch)
- Editor of the texts:
- Advances in Cerebral Aneurysm Treatment. Intechopen (DOI: 0.5772/intechopen.106102 ISBN: 978-1-83768-737-4. Link)
- Neurosurgical procedures: innovative approaches. Intechopen (DOI: 10.5772/intechopen.78468; ISBN: 978-1-78985-928-7)
- Cerebral Circulation - Updates on Models, Diagnostics and Treatments of Related Diseases (DOI: 10.5772/intechopen.98169; ISBN: 978-1-80355-361-0)
- Editorial Board:
- Frontiers in Neurology - Neurotrauma section
- Frontiers in Neuroncology
- Current trends in Surgery – RVS Publisher
- Clinical Neurology and Neuroscience - Science PG
- Journal of Neurology Research Review & Reports - Scientific research and community
- Guest Editor
- Diagnostics: Special Issue “Brain Tumors: Diagnosis and Management”
- Frontiers in Neurology: Special Issue “Women in Neurotrauma” Link
- Cells (MDPI): Special Issue "Neurological Symptoms and COVID-19 Pandemic" Link
- Materials (MDPI): Special Issue "New Advances in Additive Manufacturing Technology" Link
- Journal of Neurosurgical Sciences (Minerva Medica): Special Issue “Neurosurgical Systematic Reviews and Meta-Analysis for a daily practice.”
- Clinical and Applied Thrombosis/Hemostasis (SAGE): Special Collection on Anticoagulants and Antithrombotic Therapy Management in Neurosurgical Patients Link
- Journal of Integrative Neuroscience - IMR Press: Special Issue: “Surgical Management of Junctional Spinal Disorders” Link
- Reviewer of scientific articles for multidisciplinary journals: BioMed Research International, Neurosciences, Journal of Neuro-oncology, JoVE, Critical Care, Interdisciplinary Neurosurgery, Neurosurgical Review, American Journal of Case Reports, Journal of Neurosurgical Sciences, Journal of Clinical Medicine JCM Link

**RESEARCH ACTIVITIES**
- Publications: 121 articles in international scientific journals Link, H index = 16, Citations: 1030 (January 15, 2025, Scopus). A total of about 50 presentations were presented as posters or communications at International and National Congresses.
- Author of Book Chapters:
- Horizons in Neuroscience Research. Volume 48. Andres Costa and Eugenio Villalba (Editors). Novapublisher. ISBN: 979-8-88697-230-6. Chapter 8. Aspirin (Acetylsalicylic Acid) in Neurosurgical Patients: Benefits and Risks for Cranial and Spinal Surgeries.
- Diagnosis and Treatment of Traumatic Brain Injury. The Neuroscience of traumatic brain injury. Elsevier. ISBN: 9780128233474 eBook ISBN: 9780128233481. Chapter15: Brain swelling in traumatic brain injury.
- Cerebral Circulation - Updates on Models, Diagnostics and Treatments of Related Diseases, Intechopen. Chapter: The Cerebral Venous System: New Pathophysiological Theories and Diseases Related to Veins Occlusion. DOI: 10.5772/intechopen.102351
- Neurosurgical procedures: innovative approaches, Intechopen. ISBN: 978-1-78985-928-7 Chapter 2. Innovations in the Surgery of Cerebral Aneurysms: Enhanced Visualization, Perfusion, and Function Monitoring. DOI: 10.5772/intechopen.91030
- Advances in Engineering Research. Volume 41. ISBN: 978-1-53618-882-0; E-BOOK ISBN: 978-1-53618-999-5. Chapter 8, The role of 3D Printing in Neurosurgery.
- From Bench to Bedside - Trauma, Tumors, Spine, Functional Neurosurgery. ISBN 978-953-51-2629-4, Print ISBN 978-953-51-2628-7. Chapter 4, Surgical Techniques in Benign Extra-Axial Tumors.
- Member and co-founder of the innovative start-up LP Tech, accredited spin-off of the University of Ferrara in March 2023.
- Patent “Silicone mold for the in-line realization of a prosthesis to be applied and method for the realization of said mold” filed in April 2023.

**MAIN FUNDED RESEARCH PROJECTS:**
- 2023 Call for research projects funded with the contribution of the Chamber of Commerce, Industry, Crafts and Agriculture of Ferrara and Ravenna. Participation as PI coordinator of the project “Development of patient-specific simulators for vascular procedures through the application of new materials and 3D printing techniques for the training of healthcare personnel and the pre-operative study of the most complex cases”. (€15,000)
- PNRR mission 6 - component 2 investment 2.1 enhancement and strengthening of biomedical research of the SSN 2022. Project title: “Brain Lesions Border Characterization: Intraoperative Electrophysiology and Off-line Neurobiology – BLBC”, in collaboration with the Besta Neurological Institute of Milan and other qualified Italian institutions. (Project code: PNRR-POC-2022-12376380). Project manager Prof. Francesco Di Meco.
Role: participant in the Neurosurgery operational unit of the University of Ferrara.
The project was approved with a valid score of 8.0, duration of 24 months and funding of €980,000.
- PRIN 2022 PNRR Mission 4 – Component 2. From Research to Business - Intervention 1.1 Fund for the National Research Program (PNR) and Projects of Relevant National Interest (PRIN). Project title: “3DPRIN - 3DPRINting of multi-material parts for cranial implants”, in collaboration with the University of Brescia and other qualified Italian institutions. (Project code: P2022PMMWX). Project manager Prof. Antonio Fiorentino.
Role: PI responsible for the Neurosurgery operational unit of the University of Ferrara.
The project was approved with a score of 95, duration of 24 months and funding of €225,000.
- Start Cup Emilia-Romagna 2022 Call. Participation as PI coordinator of the project “New methodologies for the low-cost production of patient-specific cranioplasties in polymethylmethacrylate”. Second place. (€6,000)
- Call for the funding of scientific research “Fund for the Incentive to Departmental Research” (FIRD) – year 2022 with the project: “Artificial Intelligence for Meta-Researches”. (€4,357)

**MAIN RESEARCH INTERESTS AND NATIONAL AND INTERNATIONAL COLLABORATIONS**
1. Participation in the international multicenter research group iCORIC (international collaborative research initiative on CSDH), which promotes studies, surveys, and consensus conferences on the pathology of chronic subdural hematomas.
2. Direction and coordination of the Italian multicenter research group for prospective observational study: “Application of Artificial Intelligence algorithms for the determination of the bleeding risk of cerebral cavernomas” ongoing at the Neurosurgery Department and the Department of Translational Medicine and for Romagna of the University of Ferrara in collaboration with: Policlinico Universitario A. Gemelli of Rome, Santo Spirito Hospital of Pescara, Sant’Andrea Hospital of Rome, Azienda Socio Sanitaria Territoriale degli Spedali Civili of Brescia, IRCCS San Martino Hospital of Genoa, ASST Grande Ospedale Maggiore Niguarda of Milan.
3.Direction and coordination of the international multicenter research group for a randomized clinical trial: “Intraoperative monitoring of the sensory area during awake surgery: use of a new neuropsychological test” ongoing at the Neurosurgery Department and the Department of Translational Medicine and for Romagna of the University of Ferrara in collaboration with

**4.** Direction and coordination of the Italian multicenter research group for a prospective observational study on the timing of suspension and resumption of anticoagulants and antiplatelet agents in patients undergoing surgery for chronic subdural hematoma and its influence on clinical outcomes at the Neurosurgery Department and the Department of Morphology, Surgery, and Experimental Medicine of the University of Ferrara in collaboration with: Bufalini Hospital of Cesena, ULSS Berica 8 Company of Vicenza, Santa Maria della Misericordia Hospital of Udine, Policlinico Universitario A. Gemelli of Rome, Santo Spirito Hospital of Pescara.

**5.** Participation as the responsible investigator for the Neurosurgery Department of the Sant’Anna University Hospital of Ferrara, in the international clinical trial RESURGE – Randomized Controlled Comparative Phase II Trial on Surgery for Glioblastoma Recurrence (REGISTRATION: ClinicalTrials.gov and www.kofam.ch, Registration number – NCT02394626, Principal Investigator: Prof. Dr. med. Philippe Schucht).

**6.** Coordination of the Italian multicenter research group on the influence of nutritional status on the outcome of patients undergoing surgery for the evacuation of chronic subdural hematoma at the Neurosurgery Department and the Department of Morphology, Surgery, and Experimental Medicine of the University of Ferrara in collaboration with: Bufalini Hospital of Cesena, the Pious Foundation of Worship and Religion Cardinal G. Panico of Tricase (LE). The research group has produced a scientific publication in an international journal.

**7.** Participation in the Italian multicenter research group on DISH (diffuse idiopathic skeletal hyperostosis) at the Neurosurgery Department and the Department of Morphology, Surgery, and Experimental Medicine of the University of Ferrara in collaboration with: Bufalini Hospital of Cesena, AOUI Verona, Galeazzi Orthopedic Institute of Milan, Maggiore C.A. Pizzardi Hospital of Bologna, University of Turin, San Carlo Hospital of Potenza, Policlinico Universitario A. Gemelli, Institute of Neurological Sciences of Bologna, Sant’Andrea Hospital Sapienza of Rome, Pious Foundation of Worship and Religion Cardinal G. Panico, Tricase (LE), Alessandro Manzoni Hospital, Lecco, IRCCS San Martino Hospital, Genoa. The research group has produced a scientific publication in an international journal.

**8.** Direction and coordination of the Italian multicenter research group on the radiological outcome of posterior communicating artery (PCoA) aneurysms treated endovascularly at the Neurosurgery Department and the Department of Morphology, Surgery, and Experimental Medicine of the University of Ferrara in collaboration with: ASST Grande Ospedale Maggiore Niguarda of Milan, AULS 8 Berica Hospital of Vicenza, Catholic University of the Sacred Heart of Rome.

**9.** Direction and coordination of the research group on the etiology of perimesencephalic subarachnoid hemorrhage at the Neurosurgery Department and the Department of Morphology, Surgery, and Experimental Medicine of the University of Ferrara in collaboration with: ASST Grande Ospedale Maggiore Niguarda of Milan, University of Brescia, Catholic University of the Sacred Heart of Rome. The research group has produced a scientific publication in an international journal.

**10.** Direction and coordination of the research group on 3D printing of complex cerebral aneurysms at the Neurosurgery Department of the University of Ferrara in collaboration with: Catholic University of the Sacred Heart of Rome, Enterprise Engineering of the University of Tor Vergata of Rome, and Engineering of the Niccolò Cusano University of Rome. The collaboration has led to publications, conference presentations, and the collaboration for the presentation of a project (directed and coordinated by Prof. Marco Evangelos Biancolini) for participation in the Horizon 2020 “Marie Skłodowska-Curie Innovative Training Networks” call with the proposal titled “The Medical Digital Twin for Aneurysm prevention and Treatment (MEDITATE)”. Among the partners of the initiative is the University of Rome Tor Vergata (Prof. M. E. Biancolini) and other qualified national and European institutions operating in the field of Research and Training. The project was approved in May 2019 with a total score of 92.80% (Threshold: 70/100.00), a duration of 48 months, and funding.

**11.** Direction and coordination of the research group on the use of immunotherapy in brain metastases at the Neurosurgery Department of the University of Ferrara in collaboration with the Ecclesiastical Entity Regional General Hospital F. Miulli, Bari. The research group has produced a scientific publication in an international journal.

**12.** Participation in the research group on the outcome of patients treated with cervical microdiscectomy at one or two levels at the Neurosurgery Department of the University of Ferrara in collaboration with: Catholic University of the Sacred Heart of Rome, University of Messina. The research group has produced a scientific publication in an international journal.

**13.** Participation in the research group on DBS for the stimulation of the thalamic Voa nucleus in patients with dystonia at the Neurosurgery Department of the University of Ferrara in collaboration with the Meyer University Hospital of Florence. The research group has produced a scientific publication in an international journal.

**14.** Coordination of the research group on variants of the retrosigmoid approach for vascular and oncological pathologies of the posterior and middle cranial fossa at the Dardinger Microneurosurgical Skull Base Laboratory of Ohio State University. The research group (directed by Prof. Mario Ammirati) has produced 5 publications in international journals.

**15.** Coordination of the research group on the treatment and management of partially clipped cerebral aneurysms at the Catholic University of the Sacred Heart in collaboration with the San Camillo-Forlanini Hospital of Rome. The research group has produced a publication in an international journal.

**16.** Participation in the research group on the clinical and surgical management of severe head trauma at the Neurosurgery Department of the University of Ferrara in collaboration with the San Bortolo Hospital of Vicenza. The research group has produced a scientific publication in an international journal.