Pubblicazioni

  • Finotti A, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi M, Mancini I, Cabrini G, Saviano M, Avitabile C, Romanelli A, Gambari R. Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: Recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene. Artif DNA PNA XNA. 2012 Apr 1;3(2):97-296.

 

  • Gambari R, Borgatti M, Lampronti I, Fabbri E, Brognara E, Bianchi N, Piccagli L, Yuen MC, Kan CW, Hau DK, Fong WF, Wong WY, Wong RS, Chui CH. Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells. Int Immunopharmacol. 2012 Jul;13(3):308-15.

 

  • Zuccato C, Breda L, Salvatori F, Breveglieri G, Gardenghi S, Bianchi N, Brognara E, Lampronti I, Borgatti M, Rivella S, Gambari R. A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction. Ann Hematol. 2012 Aug;91(8):1201-13.

 

  • Fibach E, Prus E, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Finotti A, Lipucci di Paola M, Brognara E, Lampronti I, Borgatti M, Gambari R. Resveratrol:  Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients. Int J Mol Med. 2012 Jun;29(6):974-82.

 

  • Khan MT, Mischiati C, Ather A, Ohyama T, Dedachi K, Borgatti M, Kurita N, Gambari R. Structure-based analysis of the molecular recognitions between HIV-1 TAR-RNA and transcription factor nuclear factor-kappaB (NFkB). Curr Top Med Chem.2012;12(8):814-27.

 

  • Bianchi N, Zuccato C, Finotti A, Lampronti I, Borgatti M, Gambari R. Involvement of miRNA in erythroid differentiation. Epigenomics. 2012 Feb;4(1):51-65.

 

  • Saab AM, Lampronti I, Borgatti M, Finotti A, Harb F, Safi S, Gambari R. In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 2011 Dec 14.

 

  • Fabbri E, Brognara E, Borgatti M, Lampronti I, Finotti A, Bianchi N, Sforza S, Tedeschi T, Manicardi A, Marchelli R, Corradini R, Gambari R. miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs. Epigenomics. 2011 Dec;3(6):733-45.

 

  • Bezzerri V, Borgatti M, Finotti A, Tamanini A, Gambari R, Cabrini G. Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells. J Immunol. 2011 Dec 1;187(11):6069-81.

 

  • Saab AM, Tundis R, Loizzo MR, Lampronti I, Borgatti M, Gambari R, Menichini F, Esseily F, Menichini F. Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 2011 Oct 21.

 

  • Fabbri E, Manicardi A, Tedeschi T, Sforza S, Bianchi N, Brognara E, Finotti A, Breveglieri G, Borgatti M, Corradini R, Marchelli R, Gambari R. Modulation of the Biological Activity of microRNA-210 with Peptide Nucleic Acids (PNAs). ChemMedChem. 2011 Dec 9;6(12):2192-202.

 

  • D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R. Direct detection of point mutations in nonamplified human genomic DNA. Anal Chem. 2011 Nov 15;83(22):8711-7.

 

  • Brognara E, Lampronti I, Breveglieri G, Accetta A, Corradini R, Manicardi A, Borgatti M, Canella A, Multineddu C, Marchelli R, Gambari R. C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells. Eur J Pharmacol. 2011 Dec 15;672(1-3):30-7.

 

  • Borgatti M, Chilin A, Piccagli L, Lampronti I, Bianchi N, Mancini I, Marzaro G, dall'Acqua F, Guiotto A, Gambari R. Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects. Eur J Med Chem. 2011 Oct;46(10):4870-7.

 

  • Gambari R, Fabbri E, Borgatti M, Lampronti I, Finotti A, Brognara E, Bianchi N, Manicardi A, Marchelli R, Corradini R. Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development. Biochem Pharmacol. 2011 Nov 15;82(10):1416-29.

 

  • Borgatti M, Mancini I, Bianchi N, Guerrini A, Lampronti I, Rossi D, Sacchetti G, Gambari R. Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines. BMC Biochem. 2011 Apr 15;12:15.

 

  • Mazzitelli S, Borgatti M, Breveglieri G, Gambari R, Nastruzzi C.Encapsulation of eukaryotic cells in alginate microparticles: cell signaling by TNF-alpha through capsular structure of cystic fibrosis cells. J Cell Commun Signal. 2011 Jun;5(2):157-65.

 

  • Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'Acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G, Gambari R. Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L380-90.

 

  • Borgatti M, Breveglieri G, Salvatori F, Zuccato C, Altamura N. Therapeutic molecules for the development of a read-through approach for diseases caused by nonsense mutations. Minerva Biotecnologica 2011 Mar;23(1):11-6.

 

  • Piccagli L, Borgatti M, Nicolis E, Bianchi N, Mancini I, Lampronti I, Vevaldi D, Dall'Acqua F, Cabrini G, Gambari R. Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis. Bioorg Med Chem. 2010 Dec 1;18(23):8341-9.

 

  • Cabrini G, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Tamanini A, Lampronti I, Piccagli L, Bianchi N, Borgatti M, Gambari R. Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds. Curr Med Chem. 2010;17(35):4392-404.
  • Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A. gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions. Bioorg Chem. 2010 Oct;38(5):196-201.

 

  • Salvador A, Dall’Acqua S, Sutera Sardo M, Caffieri S, Vedaldi D,Dall’Acqua F, Borgatti M, Zuccato C, Bianchi N, Gambari R. Erythroid Induction of Chronic Myelogenous Leukemia K562 Cells Following Treatment with a Photoproduct Derived from the UV-A Irradiation of 5-Methoxypsoralen. ChemMedChem 2010;5(9):1506-12.

 

  • Destro F,  Borgatti M,  Iafelice B, Gavioli R, Braun T, Bauer J,  Bottcher  L, Jung E, Bocchi M, Guerrieri R, Gambari R. Effects of biomaterials for Lab-on-a-chip production on cell growth and expression of differentiated functions of leukemic cell lines. J. Mater Sci: Mater. Med. 2010;21(9):2653-64.

 

  • Borgatti M, Mazzitelli S, Breveglieri G, Gambari R, Nastruzzi C. Induction by TNF-alpha of IL-6 and IL-8 in cystic fibrosis bronchial IB3-1 epithelial cells encapsulated in alginate microbeads, J. Biomed. Biotechnol. 2010;2010. pii:907964.

 

  • Gambari R, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Tamanini A, Cabrini G. Decoy oligodeoxyribonucleotides and peptide nucleic acids-DNA chimeras targeting nuclear factor kappa-B: inhibition of IL-8 gene expression in Cystic Fibrosis cells infected with Pseudomonas aeruginosa. Biochem Pharmacol. 2010; 80(12):1887-94.

 

  • Ruimi N, Rwashdeh H, Wasser S, Konkimalla B, Efferth T, Borgatti M, Gambari R, Mahajna J. Daedalea gibbosa substances inhibit LPS-induced expression of iNOS by suppression of NF-kappaB and MAPK activities in RAW 264.7 macrophage cells. Int J Mol Med. 2010 Mar;25(3):421-32.

 

  • Mangolini A, Bogo M, Durante C, Borgatti M, Gambari R, Harris PC, Rizzuto R, Pinton P, Aguiari G, del Senno L. NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells. Apoptosis. 2010 Jan;15(1):94-104.

 

  • Mazzuferi M, Bovolenta R, Bocchi M, Braun T, Bauer J, Jung E, Iafelice B, Guerrieri R, Destro F, Borgatti M, Bianchi N, Simonato M, Gambari R. The biocompatibility of materials used in printed circuit board technologies with respect to primary neuronal and K562 cells. Biomaterials. 2010 Feb;31(6):1045-54.

 

  • Salvatori F, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Brognara E, Lampronti I, Breda L, Rivella S, Gambari R. Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients. Am J Hematol. 2009 Nov;84(11):720-8.

 

  • Piccagli L, Fabbri E, Borgatti M, Bianchi N, Bezzerri V, Mancini I, Nicolis E, Dechecchi CM, Lampronti I, Cabrini G, Gambari R. Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes. ChemMedChem. 2009 Dec;4(12):2024-33.

 

  • Lampronti I, Bianchi N, Zuccato C, Dall'acqua F, Vedaldi D, Viola G, Potenza R, Chiavilli F, Breveglieri G, Borgatti M, Finotti A, Feriotto G, Salvatori F, Gambari R. Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs. Int J Hematol. 2009 Oct;90(3):318-27.

 

  • Rizzo R, Dal Canto MB, Stignani M, Fadini R, Fumagalli D, Renzini MM, Borgatti M, Gambari R, Baricordi OR. Production of sHLA-G molecules by in vitro matured cumulus-oocyte complex. Int J Mol Med. 2009 Oct;24(4):523-30.

 

  • Borgatti M, Rizzo R. Investigations on sHLA-G and sICAM-1 levels in human oocytes and embryos. Minerva Biotecnologica. 2009 Sep;  21(3):161-71.

 

  • Piva R, Penolazzi L, Borgatti M, Lampronti I, Lambertini E, Torreggiani E, Gambari R. Apoptosis of human primary osteoclasts treated with molecules targeting nuclear factor-kappaB. Ann N Y Acad Sci. 2009 Aug;1171:448-56.

 

  • Viola G, Salvador A, Vedaldi D, Dall'Acqua F, Bianchi N, Zuccato C, Borgatti M, Lampronti I, Gambari R. Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives. Ann N Y Acad Sci. 2009 Aug;1171:334-44.

 

  • Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen. Int Immunopharmacol. 2009 Nov;9(12):1411-22.

 

  • Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of -Thalassemia and Sickle-Cell Anemia. Evid Based Complement Alternat Med. 2009 Jun; 6(2):141-51.

 

  • Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. Expression of miR-210 during erythroid differentiation and induction of gamma-globin gene expression. BMB Rep. 2009 Aug 31;42(8):493-9.

 

  • Guerrini A, Lampronti I, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Mancini I, Rossi D, Potenza R, Chiavilli F, Sacchetti G, Gambari R, Borgatti M. Bergamot (Citrus bergamia Risso) Fruit Extracts as gamma-Globin Gene Expression Inducers: Phytochemical and Functional Perspectives. J Agric Food Chem. 2009;  57:4103-11.

 

  • Salvatori F, Cantale V, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Breda L, Rivella S, Gambari R. Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassemia mutation for the screening of correctors of stop codon mutations. Biotechnol Appl Biochem. 2009 Jul 9;54(1):41-52.

 

  • Borgatti M, Finotti A, Falzarano S, Selvatici R. Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor. Biochimie. 2009 Apr; 91(4):466-74.

 

  • Bianchi N, Borgatti M, Fibach E, Prus E, Zuccato C, Breveglieri G, Baraldi PG, Romagnoli R, Gambari R. Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: induction of production of fetal hemoglobin in human erythroid precursor cells. Int J Mol Med. 2009 Jan;23(1):105-11.

 

  • Accetta A, Corradini R, Sforza S, Tedeschi T, Brognara E, Borgatti M, Gambari R, Marchelli R. New uracil dimers showing erythroid differentiation inducing activities. J Med Chem. 2009 Jan 8;52(1):87-94.

 

  • Borgatti M, Rizzo R, Canto MB, Fumagalli D, Renzini MM, Fadini R, Stignani M, Baricordi OR, Gambari R. Release of sICAM-1 in oocytes and in vitro fertilized human embryos. PLoS ONE. 2008;3(12):e3970.

 

  • Penolazzi L, Lampronti I, Borgatti M, Khan MT, Zennaro M, Piva R, Gambari R. Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis. BMC Complement Altern Med. 2008 Oct 30;8:59.

 

  • Lampronti I, Khan MT, Borgatti M, Bianchi N, Gambari R. Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences. Evid Based Complement Alternat Med. 2008 Sep;5(3):303-312.

 

  • Fabbri E, Borgatti M, Manaresi N, Medoro G, Nastruzzi C, Di Croce S, Tosi A, Mazzitelli S, Mancini I, Guerrieri R, Gambari R. Levitation and movement of tripalmitin-based cationic lipospheres on a dielectrophoresis-based lab-on-a-chip device. J Appl  Polym Sci. 2008 Sep; 109(6):3484-91.

 

  • Dechecchi MC, Nicolis E, Norez C, Bezzerri V, Borgatti M, Mancini I, Rizzotti P, Ribeiro CM, Gambari R, Becq F, Cabrini G. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 2008 Nov;7(6):555-65.

 

  • Piccagli L, Fabbri E, Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Cabrini G, Gambari R. Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA  interactions and inhibitory effects on IL-8 gene expression. BMC Struct Biol. 2008 Sep 3;8:38.

 

  • Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bianchi N, Bezzerri V, Mancini I, Grazia Giri M, Rizzotti P, Gambari R, Cabrini G. Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells. Int Immunopharmacol. 2008 Dec 10;8(12):1672-80.

 

  • Breveglieri G, Salvatori F, Finotti A, Bertuzzi I, Destro F, Falzoni S, Bianchi N, Borgatti M, Zuccato C, Feriotto G, Breda L, Rivella S, Gambari R. Cellular biosensors for the identification of fetal hemoglobin inducers. Minerva Biotecnologica. 2008 Dec;19 (4):123-132.

 

  • Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R. PNAs targeting the "RNA world": micro RNA next? Minerva Biotecnologica. 2008 Dec; 20 (4):183-188.

 

  • Viola G, Vedaldi D, Dall'acqua F, Lampronti I, Bianchi N, Zuccato C, Borgatti M, Gambari R. Furocoumarins photolysis products induce differentiation of human erythroid cells. J Photochem Photobiol B. 2008 Jul 24;92(1):24-8.

 

  • Bezzerri V, Borgatti M, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Rizzotti P, Gambari R, Cabrini G. Transcription Factor Oligodeoxynucleotides to NF-{kappa}B Inhibit Transcription of IL-8 in Bronchial Cells. Am J Respir Cell Mol Biol. 2008 Jul;39(1):86-96.

 

  • Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Rizzotti P, Lampronti I, Gambari R, Cabrini G. Silencing of genes coding for transcription factors: biological effects of decoy oligonucleotides on cystic fibrosis bronchial epithelial cells. Minerva Biotecnologica. 2008 Jun;20(2):79-83.

 

  • Feriotto G, Salvatori F, Finotti A, Breveglieri G, Venturi M, Zuccato C, Bianchi N, Borgatti M, Lampronti I, Mancini I, Massei F, Favre C, Gambari R. A Novel Frameshift Mutation (+A) at Codon 18 of the beta-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and deltabeta-Thalassemia. Acta Haematol. 2008 Jan 30;119(1):28-37.

 

  • Borgatti M, Bianchi N, Mancini I, Feriotto G, Gambari R. New trends in non-invasive prenatal diagnosis: applications of dielectrophoresis-based Lab-on-a-chip platforms to the identification and manipulation of rare cells. Int J Mol Med. 2008 Jan;21(1):3-12.

 

  • Viola G, Vedaldi D, Dall'acqua F, Fortunato E, Basso G, Bianchi N, Zuccato C, Borgatti M, Lampronti I, Gambari R. Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives. Biochem Pharmacol. 2008 Feb 15;75(4):810-25.

 

  • Bianchi N, Borgatti M, Gambari R Gene silencing in thalassemia. Minerva Biotecnologica. 2008 Mar;20(1):51-55.

 

  • Moggio L, Romanelli A, Gambari R, Bianchi N, Borgatti M, Fabbri E, Mancini I, di Blasio B, Pedone C, Messere A. Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity. Biopolymers. 2007;88(6):815-22.

 

  • Borgatti M, Manaresi N, Medoro G, Mancini I, Fabbri E, Guerrieri R, Gambari R. Dielectrophoresis based Lab-on-a-chip platforms for the identification and manipulation of rare cells and microspheres: implications for non-invasive prenatal diagnosis. Minerva Biotecnologica. 2007 Jun; 19(2):43-49.

 

  • Dechecchi MC, Nicolis E, Bezzerri V, Vella A, Colombatti M, Assael BM, Mettey Y, Borgatti M, Mancini I, Gambari R, Becq F, Cabrini G. MPB-07 reduces the inflammatory response to Pseudomonas aeruginosa in cystic fibrosis bronchial cells. Am J Respir Cell Mol Biol. 2007 May;36(5):615-24.

 

  • Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Induction of IL-6 gene expression in a CF bronchial epithelial cell line byPseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1superfamily. Biochem Biophys Res Commun. 2007 Jun 15;357(4):977-83.

 

  • Borgatti M, Rizzo R, Mancini I, Fabbri E, Baricordi O, Gambari R. 1,3 Antibody-antigen interactions in dielectrophoresis buffers for cell manipulation on dielectrophoresis-based Lab-on-a-chip devices. Minerva Biotecnologica. 2007 Jun; 19(2):71-74.

 

  • Zuccato C, Bianchi N, Borgatti M, Lampronti I, Massei F, Favre C, Gambari R. Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells. Acta Haematol. 2007;117(3):168-76.

 

  • Messere A, Fabbri E, Borgatti M, Gambari R, Di Blasio B, Pedone C, Romanelli A. Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine. J Inorg Biochem. 2007 Feb;101(2):254-60.

 

  • Nastruzzi C, Tosi A, Borgatti M, Guerrieri R, Medoro G, Gambari R. Applications of Dielectrophoresis-based Lab-on-a-chip Devices in Pharmaceutical Sciences and Biomedicine. In:  CMOS Biotechnology, Edited by Lee H, Ham D, Westervelt RM, Springer Science+Business Media, LLC, New York, NY. 2007; pp.145-178 .

 

  • Gambari R, Borgatti M , Fabbri E, Gavioli R, Fortini C, Nastruzzi C, Altomare L , Abonnenc M, Manaresi N, Medoro G, Romani A, Tartagni M, Guerrieri R. “Lab-on-a-chip” Devices for cellular arrays based on dielectrophoresis. In: Bioarrays-From Basic to Diagnostic, Edited by Appasani K, Humana Press Inc, Totowa, NJ. 2007; pp.231- 243.

 

  • Lampronti I, Khan MTH, Bianchi N, Feriotto G, Mischiati C, Borgatti M, Gambari R. Effects of medical plant extracts on molecular interactions between DNA and transcription factors. In: Lead Molecules from Natural Products: discovery and new trends- Advances in phytomedicine. Vol.2, Edited by Khan MTH, Ather A, Elsevier, Oxford, UK. 2006; pp.35-44.

 

  • Lampronti I, Khan MTH, Bianchi N, Lambertini E, Piva R, Borgatti M, Gambari R. Plants with antitumor properties: from biologically active molecules to drugs. In: Lead Molecules from Natural Products: discovery and new trends-Advances in phytomedicine. Vol.2, Edited by Khan MTH, Ather A, Elsevier, Oxford, UK. 2006; pp.45-64.

 

  • Piva R, Penolazzi L, Zennaro M, Bianchini E, Magri E, Borgatti M, Lampronti I, Lambertini E, Tavanti E, Gambari R. Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules. Ann N Y Acad Sci. 2006 Dec;1091:509-16.

 

  • Fibach E, Bianchi N, Borgatti M, Zuccato C, Finotti A, Lampronti I, Prus E, Mischiati C, Gambari R. Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients. Eur J Haematol. 2006 Nov;77(5):437-41.

 

  • Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents. J Med Chem. 2006 Jun 29;49(13):3906-15.

 

  • Ronchetti D, Impagnatiello F, Guzzetta M, Gasparini L, Borgatti M, Gambari R, Ongini E. Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages. Eur J Pharmacol. 2006 Feb 17;532(1-2):162-9.

 

  • Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R. Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor(uPAR) promoter. Oncol Res. 2005;15(7-8):373-83.

 

  • Di Croce S, Tosi A, Bilancetti L, Mazzitelli S, Bozzuto N, Borgatti M, Fabbri E, Mancini I, Gambari R, Nastruzzi C. Cellulose acetate microparticles for lab-on-a-chip applications. Minerva Biotecnologica. 2005 Dec; 17(4):259-269.

 

  • Romagnoli R, Baraldi PG, Tabrizi MA, Bermejo J, Estevez F, Borgatti M, Gambari R. Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and alpha-bromoacryloyl moieties. J Med Chem. 2005 Dec 1;48(24):7906-10.

 

  • Cozzani M, Giovannini I, Naccari R, Penolazzi L, Lambertini E, Borgatti M, Piva R, Gambari R, Siciliani G. Transcription Factor Decoy (TFD) as a novel approach for the control of osteoclastic resorption. Prog Orthod. 2005;6(2):238-47.

 

  • Borgatti M, Altomare L, Abonnec M, Fabbri E, Manaresi N, Medoro G, Romani A, Tartagni M, Nastruzzi C, Di Croce S, Tosi A, Mancini I, Guerrieri R, Gambari R. Dielectrophoresis-based 'Lab-on-a-chip' devices for programmable binding of microspheres to target cells. Int J Oncol. 2005 Dec;27(6):1559-66.

 

  • Romagnoli R, Baraldi PG, Iaconinoto MA, Carrion MD, Tabrizi MA, Gambari R, Borgatti M, Heilmann J. Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates. Eur J Med Chem. 2005 Nov;40(11):1123-8.

 

  • Lampronti I, Bianchi N, Borgatti M, Fabbri E, Vizziello L, Khan MT, Ather A, Brezena D, Tahir MM, Gambari R. Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions. Oncol Rep. 2005 Jul;14(1):9-15.

 

  • Lampronti I, Khan MT, Bianchi N, Ather A, Borgatti M, Vizziello L, Fabbri E,  Gambari R. Bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kappaB binding sites. Med Chem. 2005 Jul;1(4):327-33.

 

  • Borgatti M, Altomare L, Baruffa M, Fabbri E, Breveglieri G, Feriotto G, Manaresi N, Medoro G, Romani A, Tartagni M, Gambari R, Guerrieri R. Separation of white blood cells from erythrocytes on a dielectrophoresis (DEP) based 'Lab-on-a-chip' device. Int J Mol Med. 2005 Jun;15(6):913-20.

 

  • Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R. Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression. Curr Drug Targets. 2004 Nov;5(8):735-44.

 

  • Mischiati C, Sereni A, Finotti A, Breda L, Cortesi R, Nastruzzi C,Romanelli A, Saviano M, Bianchi N, Pedone C, Borgatti M, Gambari R. Complexation to cationic microspheres of double-stranded peptide nucleic acid-DNA chimeras exhibiting decoy activity. J Biomed Sci. 2004 Sep-Oct;11(5):697-704.

 

  • Lampronti I, Khan MTH, Bianchi N, Borgatti M, Gambari R. Inhibitory effects of medicinal plant extracts on interactions between DNA and transcription factors involved in inflammation. Minerva Biotecnologica. 2004 Jun;16(2):93-99.

 

  • Mischiati C, Sereni A, Lampronti I, Bianchi N, Borgatti M, Prus E, Fibach E, Gambari R. Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells. Br J Haematol. 2004 Aug;126(4):612-21.

 

  • Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R. Peptide nucleic acid-DNA decoy chimeras targeting NF-kappaB transcription factors: Induction of apoptosis in human primary osteoclasts. Int J Mol Med. 2004 Aug;14(2):145-52.

 

  • Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C. Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles. AAPS PharmSci. 2004 Jan 20;6(1):E2.

 

  • Mischiati C, Finotti A, Sereni A, Boschetti S, Baraldi PG, Romagnoli R, Feriotto G, Jeang KT, Bianchi N, Borgatti M, Gambari R. Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA. Biochem Pharmacol. 2004 Feb 1;67(3):401-10.

 

  • Lambertini E, Piva R, Khan MT, Lampronti I, Bianchi N, Borgatti M, Gambari R. Effects of extracts from Bangladeshi medicinal plants on in vitro proliferation of human breast cancer cell lines and expression of estrogen receptor alpha gene. Int J Oncol. 2004 Feb;24(2):419-23.

 

  • Tomassetti M, Feriotto G, Giacomini P, Giorda E, Bianchi N, Borgatti M, Finotti A, Mischiati C, Gambari R. Identification of a novel DNase I hypersensitive site within the far upstream region of the human HLA-DRA gene. Int J Mol Med. 2003 Dec;12(6):929-34.

 

  • Borgatti M, Rutigliano C, Bianchi N, Mischiati C, Baraldi PG, Romagnoli R, Gambari R. Inhibition of NF-kB/DNA interactions and HIV-1 LTR directed transcription by hybrid molecules containing pyrrolo [2,1-c] [1,41 benzodiazepine (PRD) and oligopyrrole carriers. Drug Dev Res. 2003 Nov;60(3):173-185.

 

  • Penolazzi L, Lambertini E, Borgatti M, Piva R, Cozzani M, Giovannini I, Naccari R, Siciliani G, Gambari R. Decoy oligodeoxynucleotides targeting NF-kappaB transcription factors:induction of apoptosis in human primary osteoclasts. Biochem Pharmacol. 2003 Oct 1;66(7):1189-98.

 

  • Lampronti I, Bianchi N, Borgatti M, Fibach E, Prus E, Gambari R. Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin. Eur J Haematol. 2003 Sep;71(3):189-95.

 

  • Chiarabelli C, Bianchi N, Borgatti M, Prus E, Fibach E, Gambari R. Induction of gamma-globin gene expression by tallimustine analogs in human erythroid cells. Haematologica. 2003 Jul;88(7):826-7.

 

  • Bianchi N, Borgatti M, Gambari R.Quantitative RT-PCR for the analysis of expression of alpha-, beta- and gamma-globin genes in erythroid cells. Minerva Biotecnologica. 2003 Jun;15(2):137-144.

 

  • Lampronti I, Martello D, Bianchi N, Borgatti M, Lambertini E, Piva R, Jabbar S, Choudhuri MS, Khan MT, Gambari R. In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa. Phytomedicine. 2003 May;10(4):300-8.

 

  • Fibach E, Bianchi N, Borgatti M, Prus E, Gambari R. Mithramycin induces fetal hemoglobin production in normal and thalassemic human erythroid precursor cells. Blood. 2003 Aug 15;102(4):1276-81.
  • Borgatti M, Romanelli A, Saviano M, Pedone C, Lampronti I, Breda L, Nastruzzi C, Bianchi N, Mischiati C, Gambari R. Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum. Oncol Res. 2003;13(5):279-87.

 

  • Altomare L, Borgatti M, Medoro G, Manaresi N, Tartagni M, Guerrieri R, Gambari R. Levitation and movement of human tumor cells using a printed circuit board device based on software-controlled dielectrophoresis. Biotechnol Bioeng. 2003 May 20;82(4):474-9.

 

  • Gambari R, Borgatti M, Altomare L, Manaresi N, Medoro G, Romani A, Tartagli M, Guerrieri R. Applications to cancer research of "lab-on-a-chip" devices based on dielectrophoresis (DEP). Technol Cancer Res Treat. 2003 Feb;2(1):31-40.

 

  • Borgatti M, Lampronti I, Romanelli A, Pedone C, Saviano M, Bianchi N, Mischiati C, Gambari R. Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites. J Biol Chem. 2003 Feb 28;278(9):7500-9.

 

  • Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R. Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors. Biochem Pharmacol. 2002 Aug 15;64(4):609-16.

 

  • Mischiati C, Borgatti M, Feriotto G, Rutigliano C, Breda L, Bianchi N, Gambari R. Inhibition of HIV-1 LTR-driven in vitro transcription by molecular hybrids based on peptide nucleic acids mimicking the NF-kappaB binding site. Int J Mol Med. 2002 Jun;9(6):633-9.

 

  • Feriotto G, Borgatti M, Mischiati C, Bianchi N, Gambari R. Biosensor technology and surface plasmon resonance for real-time detection of genetically modified Roundup Ready soybean gene sequences. J Agric Food Chem. 2002 Feb 27;50(5):955-62.

 

  • Catelani G, D'Andrea F, Mastrorilli E, Bianchi N, Chiarabelli C, Borgatti M, Martello D, Gambari R. Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-beta-D-galactopyranoside and 2,3-O isopropylidene-D-mannofuranose. Bioorg Med Chem. 2002 Feb;10(2):347-53.

 

  • Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R. Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites. Eur J Biochem. 2001 Dec;268(23):6066-75.

 

  • Mischiati C, Jeang KT, Feriotto G, Breda L, Borgatti M, Bianchi N, Gambari R. Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA. Antisense Nucleic Acid Drug Dev. 2001 Aug;11(4):209-17.

 

  • Bianchi N, Chiarabelli C, Borgatti M, Mischiati C, Fibach E, Gambari R. Accumulation of gamma-globin mRNA and induction of erythroid Differentiation after treatment of human leukaemic K562 cells with tallimustine. Br J Haematol. 2001 Jun;113(4):951-61.

 

  • Saviano M, Romanelli A, Bucci E, Pedone C, Mischiati C, Bianchi N, Feriotto G, Borgatti M, Gambari R. Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-kappaB binding sites. J Biomol Struct Dyn. 2000 Dec;18(3):353-62.

 

  • Mischiati C, Feriotto G, Borgatti M, Giacomini P, Gambari R. Characterization of a major histocompatibility complex class II X-box-binding protein enhancing tat-induced transcription directed by the human immunodeficiency virus type 1 long terminal repeat. J Virol. 2000 Oct;74(19):8989-9001.

 

  • Nastruzzi C, Cortesi R, Esposito E, Gambari R, Borgatti M, Bianchi N, Feriotto G, Mischiati C. Liposomes as carriers for DNA-PNA hybrids. J Control Release. 2000 Aug 10;68(2):237-49.

 

  • Mischiati C, Rutigliano C, Feriotto G, Borgatti M, Bianchi N, Gambari R. Effects of peptide nucleic acids (PNAs) on gene transcription. Minerva Biotecnologica. 1999 Sep;11(3):205-210.

 

  • Mischiati C, Borgatti M, Bianchi N, Rutigliano C, Tomassetti M, Feriotto G,Gambari R. Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter. J Biol Chem. 1999 Nov 12;274(46):33114-22.