Pubblicazioni scientifiche
1. Kozikowski, A.P.; Simoni, D.; Baraldi, P.G.; Lampronti, I.; Manfredini, S.. A PLE-based resolution of cocaine, pseudococaine and 6-and 7-methoxylated cocaine analogues. Bioorg. Med. Chem. Lett., 6, 441-444 (1996).
2. Invidiata, F.P.; Furnò, G.; Simoni, D.; Lampronti, I.; Musiu, C.; Milia, C.; Scintu, F.; La Colla, P.; 3,6-disustituted 1,2,4-triazol[3,4-b] [1,3,4]thiadiazoles: synthesis and evaluation for antimicrobial and antiviral activity. III. Il Farmaco, 52,4, 259-261 (1997).
3. Invidiata, F.P.; Furnò, G.; Lampronti, I.; Simoni, D.; 1,2,4-triazoles. Improved synthesis of 5-substituited 4-amino-3mercato-(4H)-1,2,4 triazoles and a facile route to 3,6-disubstituited 1,24-triazolo[3,4b][1,3,4]thiadiazoles. Journal of Heterocyclic Chem. 34, 1255-1258 (1997).
4. Simoni, D.; Invidiata, F.P.; Manfredini, S.; Ferroni, R.; Lampronti, I.; Roberti, M.; Pollini, G.P.; Facile synthesis of 2-nitroalkanols by Tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones. Tetrahedron Letters, 38, 2749-2752 (1997).
5. Simoni, D.; Invidiata, F.P.; Manferdini, M.; Lampronti, I.; Rondanin, R.; Roberti, M.; Pollini, G.P.; Tetramethylguanidine (TMG)-catalyzed addition of dialkyl phosphites to a,b-unsaturated carbonyl compounds, alkenenitriles, aldehydes, ketones and imines. Tetrahedron Letters, 39, 7615-7618 (1998).
6. Manfredini, S.; Lampronti, I.; Vertuani, S.; Solaroli, N.; Recanatini, M.; Bryan, D.; McKinney, M.; Design, synthesis and binding at cloned muscarinic receptors of N-[5-(1’-substituted-acetoxymethyl)-3-oxadiazolyl] and of N-[4-(1’-substituted-acetoxymethyl)-2-dioxolanyl] dialkyl amines. Bioorg. Med. Chem. 8, 1559-1566 (2000).
7. Baraldi, P.G.; Zaid, A.N.; Lampronti, I.; Fruttarolo, F.; Pavani, M.G.; Tabrizi, M.A.; Shryock, J.C.; Leung, E.; Romagnoli, R. Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-Adenosine receptor. Bioorg. Med. Chem. Lett. 10, 1953-1957 (2000).
8. Khan, MTH.; Lampronti, I.; Martello, D.; Bianchi, N.; Jabbar, S.; Choudhuri, MSK.; Datta, BK.; Gambari, R. Identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant Emblica Officinalis: effects on in vitro cell growth of human tumor cell lines. Int. J. Oncol. 20, 187-192 (2002).
9. Borgatti, M.; Lampronti, I.; Romanelli A.; Pedone C.; Saviano, M.; Bianchi, N.; Mischiati, C.; Gambari, R. Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimiking Sp1 binding sites. J. Biol. Chem. 278, 7500-7509 (2003).
10. Borgatti, M.; Romanelli A.; Saviano, M.; Pedone C.; Lampronti, I.; Breda, L.; Nastruzzi, C.; Bianchi, N.; Mischiati, C.; Gambari, R. Resistence of Decoy PNA-DNA Chimeras to enzymatic degradation in cellular extracts and serum. Oncol. Res. 13, 279-87 (2003).
11. Lampronti, I.; Martello, D.; Bianchi, N.; Borgatti, M.; Lambertini, E.; Piva, R.; Jabbar, S.; Choudhuri, MSK.; Khan, MTH.; Gambari, R. In vitro antiproliferative effects on human tumor cell lines of extracts from the bangladeshi medicinal plant Aegle marmelos Correa. Phytomedicine. 10, 300-308 (2003).
12. Lampronti, I.; Bianchi, N.; Borgatti M.; Fibach E.; Prus E. Gambari R. Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin. Eur. J. Haematol. 71: 189-195 (2003).
13. Lambertini, E.; Piva R.; Khan, M.T.H.; Lampronti, I.; Bianchi, N.; Borgatti, M.; Gambari, R. Effects of estracts from Bangladeshi medicinal plants on in vitro proliferation of human breast cancer cell lines and expression of estrogen receptor a gene. Int. J. Oncol., 24, 419-23 (2004).
14. Lampronti, I.; Khan, MTH; Bianchi, N.; Borgatti, M; Gambari, R. Inhibitory effects of medicinal plant extracts on interactions between DNA and trancription factors involved in inflammation. Minerva Biotecnologica, 16, 93-99 (2004).
15. Mischiati, C.; Sereni, A.; Lampronti, I.; Bianchi, N.; Borgatti, M.; Prus, E.; Fibach, E.; Gambari, R. Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells. Br. J. Haematol., 126, 612-21 (2004).
16. Borgatti, M.; Finotti, A.; Romanelli, A.; Saviano, M.; Bianchi, N.; Lampronti, I.; Lambertini, E.; Penolazzi, L., Nastruzzi, C.; Mischiati, C.; Piva, R.; Pedone, C., Gambari, R. Peptide Nucleic Acids (PNA)-DNA Chimeras Targeting Transcription Factors as a Tool to Modify Gene Expression. Curr. Drug Targets, 5, 553-558 (2004).
17. Lampronti, I.; Bianchi, N.; Borgatti, M.; Fabbri, E.; Vizziello, L.; Khan, M.T.; Ather, A.; Brezena, D.; Tahir, M.M.; Gambari, R. Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions. Oncology Reports, 14: 9-15 (2005)
18. Lampronti, I.; Khan, M.T.H.; Bianchi, N.; Ather, A.; Borgatti, M.; Vizziello, L.; Fabbri, E.; Gambari, R. Bangladeshi medicinal plants extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kB binding sites. Medicinal Chemistry, 1: 327-333 (2005).
19. Lampronti, I.; Saab, A.; Gambari, R. Medicinal plants from Lebanon: effects of essential oils from Pistacia palaestina on proliferation and erythroid differentiation of human leukemic K562. Minerva Biotecnologica, 17: 153-158 (2005).
20. Lampronti, I., Rashed, K.; Gambari, R., Said A. Antiproliferative activity of Ailanthus excelsa (Roxb). Minerva Biotecnologica, 17: 175-182 (2005).
21. Lambertini, E.; Lampronti, I.; Penolazzi L.; Khan M.T.H.; Ather A.; Giorgi G.; Gambari R.; Piva R. Expression of Estrogen Receptor a Gene in Breast Cancer Cells Treated with Transcription Factor Decoy is modulated by Bangladeshi Natural Plant Extracts. Oncology Research. 14: 69-79 (2005).
22. Borgatti, M.; Boyd D.D.; Lampronti, I.; Bianchi, N.; Fabbri, E.; Saviano, M.; Romanelli, S.; Pedone, C.; Gambari, R. Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator (uPAR) promoter. Oncology Research. 15:373-83 (2005).
23. Lampronti, I.; Khan, MTH.; Bianchi, N.; Lambertini, E.; Piva, R.; Borgatti, M.; Gambari, R. Plants with antitumor properties: from biologically active molecoles to drugs. Lead molecules from natural products: Discovery and New trends. Advances in Phytomedicine Series, Elsevier, Volume 2: 45-63 (2006).
24. Mischiati, C.; Sereni, A., Khan, MTH.; Lampronti, I.; Gambari, R. Effects of plant extracts on gene expression profiling: from macroarray to microarray technology. Lead molecules from natural products: Discovery and New trends. Advances in Phytomedicine Series, Elsevier, Volume 2: 21-33 (2006).
25. Lampronti, I.; Khan, MTH.; Bianchi, N.; Feriotto, G.; Mischiati, C.; Borgatti, M.; Gambari, R. Effects of medicinal plant extracts on molecular interactions between DNA and transcription factors. Lead molecules from natural products: Discovery and New trends. Advances in Phytomedicine Series, Elsevier, Volume 2: 35-43 (2006).
26. Gambari, R. and Lampronti, I. Inhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plant extracts and plant-derived compounds. Lead molecules from natural products: Discovery and New trends. Advances in Phytomedicine Series, Elsevier, Volume 2: 299-311 (2006).
27. Lampronti, I.; Bianchi, N.; Zuccato, C.; Medici, A.; Bergamini, P.; Gambari, R. Effects on erytroid differentiation of Platinum(II) complexes of synthetic bile acids derivatives. Bioorganic and Medicinal Chemistry. 14: 5204-10 (2006).
28. Dalla Via L.; Mammi S.; Uriarte E.; Santana L., Lampronti I.; Gambari R.; Gia O. New furan side tetracyclic allopsoralen derivatives: synthesis and photobiological evaluation. J. Med. Chem. 49:4317-4326 (2006).
29. Lampronti I.; Saab A.M.; Gambari R. Antiproliferative activity of essential oils derived from plants belonging to the Magnioliophyta division. Int. J. of Oncology 29:989-995 (2006).
30. Fibach E, Bianchi N, Borgatti M, Zuccato C, Finotti A, Lampronti I, Prus E, Mischiati C, Gambari R. Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients. Eur J Haematol.; 77:437-441 (2006).
31. Piva R, Penolazzi L, Zennaro M, Bianchini E, Magri E, Borgatti M, Lampronti I, Lambertini E, Tavanti E, Gambari R. Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules. Ann N Y Acad Sci.;1091:509-16 (2006).
32. Zuccato C, Bianchi N, Borgatti M, Lampronti I, Massei F, Favre C, Gambari R. Everolimus is a Potent Inducer of Erythroid Differentiation and gamma-Globin Gene Expression in Human Erythroid Cells. Acta Haematol. ;117:168-176 (2007).
33. Borgatti, M., Bezzerri V., Mancini, I., Nicolis, E., Dechecchi, MC., Lampronti, I., Rizzotti, P., Cabrini, G., Gambari, R. Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily. Biochem. Biophys. Res. Commun. 357:977-83 (2007).
34. Previati M, Corbacella E, Astolfi L, Catozzi M, Khan MT, Lampronti I, Gambari R, Capitani S, Martini A. Ethanolic extract from Hemidesmus indicus (Linn) displays otoprotectant activities on organotypic cultures without interfering on gentamicin uptake. J Chem Neuroanat. 34:128-33 (2007).
35. Loizzo, MR.; Saab, A.; Tundis, R; Statti, GA; Lampronti, I.; Menichini, F; Gambari, R. Cinatl, J; Doerr, HW. Phytochemical analysis and in vitro evaluation of the biological activity against Herpes simplex Virus type 1 of Cedrus libani A Rich. Phytomedicine. 15:79-83 (2008).
36. Viola G, Vedaldi D, Dall'Acqua F, Fortunato E, Basso G, Bianchi N, Zuccato C, Borgatti M, Lampronti I, Gambari R. Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives. Biochem Pharmacol. 75:810-25 (2008).
37. Feriotto G, Salvatori F, Finotti A, Breveglieri G, Venturi M, Zuccato C, Bianchi N, Borgatti M, Lampronti I, Mancini I, Massei F, Favre C, Gambari R. A novel frameshift mutation (+A) at codon 18 of the beta-globin gene associated with high persistence of fetal hemoglobin phenotype and deltabeta-thalassemia. Acta Haematol. 119:28-37 (2008).
38. Bezzerri V, Borgatti M, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Rizzotti P, Gambari R, Cabrini G. Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells. Am J Respir Cell Mol Biol. 39:86-96 (2008).
39. Loizzo MR, Saab AM, Tundis R, Statti GA, Menichini F, Lampronti I, Gambari R, Cinatl J, Doerr HW. Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. Chem Biodivers. 5:461-470 (2008).
40. Viola G, Vedaldi D, Dall'Acqua F, Lampronti I, Bianchi N, Zuccato C, Borgatti M, Gambari R. Furocoumarins photolysis products induce differentiation of human erythroid cells. J Photochem Photobiol B. 92:24-28 (2008).
41. Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bianchi N, Bezzerri V, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells. Int Immunopharmacol. 8:1672-80 (2008).
42. Piccagli L, Fabbri E, Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Cabrini G, Gambari R. Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression. BMC Struct Biol. 8:38-51 (2008).
43. Lampronti, I.; Khan M.T.H.; Borgatti, M.; Bianchi, N.; Gambari, R. Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences. eCAM (Evid Based Complement Alternat Med). 5: 303-312 (2008).
44. Penolazzi L, Lampronti I, Borgatti M, Khan MTH, Zennaro M, Piva R, Gambari R. Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis. BMC Complement Altern Med. 8:59 (2008).
45. Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cruz-Lopez O, Lopez Cara C, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Gambari R, Lampronti I, Saletti R, Brancale A, Hamel E. Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization. Bioorg Med Chem. 16:8419-26 (2008).
46. Guerrini A, Lampronti I, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Mancini I, Rossi D, Potenza R, Chiavilli F, Sacchetti G, Gambari R, Borgatti M. Bergamot (Citrus bergamia Risso) Fruit Extracts as gamma-Globin Gene Expression Inducers: Phytochemical and Functional Perspectives. J Agric Food Chem. 57: 4103-4111 (2009).
47. Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of beta-Thalassemia and Sickle-Cell Anemia. eCAM (Evid based Complement Alternat Med.) 6:141-51(2009).
48. Viola G, Salvador A, Vedaldi D, Dall’Acqua F, Bianchi N, Zuccato C, Borgatti M, Lampronti I and Gambari R. Differentiation and Apoptosis in UVA-Irradiated Cells Treated with Furocoumarin Derivatives. Ann. NY. Acad. Sci. VOL. 1171, 334-344 (2009).
49. Piva R, Penolazzi L, Borgatti M, Lampronti I, Lambertini E, Torreggiani E, Gambari R. Apoptosis of Human Primary Osteoclasts Treated with Molecules Targeting Nuclear Factor-kB. Ann. NY. Acad. Sci. VOL. 1171, pag. 448-456 (2009).
50. Lampronti I; Bianchi N; Zuccato C; Dall'Acqua F; Vedaldi D; Viola G; Potenza R; Chiavilli F; Breveglieri G; Borgatti M; Finotti A; Feriotto G; Salvatori F; Gambari R. Increase in gamma-globin mRNA Content in Human Erythroid Cells Treated with Angelicin Analogs. Int J Hematology, 90: 318-327 (2009).
51. Bianchi N., Zuccato C., Lampronti I., Borgatti M., Gambari R. Expression of miR-210 during erythroid differentiation and induction of gamma-globin gene expression. BMB Reports, vol. 42(8), 493-499 (2009).
52. Piccagli L, Fabbri E, Borgatti M, Bianchi N, Bezzerri V, Mancini I, Nicolis E, Dechecchi CM, Lampronti I, Cabrini G, Gambari R. Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes. ChemMedChem.4:2024-33 (2009).
53. Salvatori F, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Brognara E, Lampronti I, Breda L, Rivella S, Gambari R. Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients. Am J Hematol. 84:720-8 (2009).
54. Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen. Int Immunopharmacol. 9:1411-22 (2009).
55. Gambari R, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Tamanini A, Cabrini G. Decoy oligodeoxyribonucleotides and peptide nucleic acids-DNA chimeras targeting nuclear factor kappa-B: inhibition of IL-8 gene expression in Cystic Fibrosis cells infected with Pseudomonas aeruginosa. Biochem Pharmacol. 80:1887-94 (2010).
56. Cabrini G, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Tamanini A, Lampronti I, Piccagli L, Bianchi N, Borgatti M, Gambari R. Targeting Transcription Factor Activity as a Strategy to Inhibit Pro-Inflammatory Genes Involved in Cystic Fibrosis: Decoy Oligonucleotides and Low-Molecular Weight Compounds. Curr Med Chem. 17:4392-404 (2010)
57. Piccagli L, Borgatti M, Nicolis E, Bianchi N, Mancini I, Lampronti I, Vevaldi D, Dall'Acqua F, Cabrini G, Gambari R. Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis. Bioorg Med Chem. 18:8341-9 (2010).
58. Anna Tamanini, Monica Borgatti, Laura Piccagli, Valentino Bezzerri, Maria Favia, Lorenzo Guerra, Ilaria Lampronti, Nicoletta Bianchi, Francesco Dall'Acqua, Daniela Vedaldi, Alessia Salvador, Enrica Fabbri, Irene Mancini, Elena Nicolis, Valeria Casavola, Giulio Cabrini, and Roberto Gambari. Trimethylangelicin Reduces IL-8 Transcription and Potentiates CFTR Function. American Journal of Physiology - Lung Cellular and Molecular Physiology 300:L380-90 (2011).
59. Borgatti M, Mancini I, Bianchi N, Guerrini A, Lampronti I, Rossi D, Sacchetti G, Gambari R. Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.
BMC Biochem. 12:15 (2011).
60. Dechecchi MC, Nicolis E, Mazzi P, Cioffi F, Bezzerri V, Lampronti I, Huang S, Wiszniewski L, Gambari R, Scupoli MT, Berton G, Cabrini G. Modulators of Sphingolipid Metabolism Reduce Lung Inflammation. Am J Respir Cell Mol Biol. 45: 825–833 (2011).
61. Borgatti M, Chilin A, Piccagli L, Lampronti I, Bianchi N, Mancini I, Marzaro G, Dall'acqua F, Guiotto A, Roberto Gambari. Development of a Novel Furocoumarin Derivative Inhibiting NF-<kappa>B Dependent Biological Functions: Design, Synthesis and Biological Effects. European Journal of Medicinal Chemistry. 46:4870-7 (2011).
62. Brognara E, Lampronti I, Breveglieri G, Accetta A, Corradini R, Manicardi A, Borgatti M, Canella A, Multineddu C, Marchelli R, Gambari R. C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells. Eur J Pharmacol. 672:30-7 (2011)
63. Gambari R, Fabbri E, Borgatti M, Lampronti I, Finotti A, Brognara E, Bianchi N, Manicardi A, Marchelli R, Corradini R. Targeting microRNAs involved in human diseases: A novel approach for modification of gene expression and drug development. Biochem Pharmacol. 82: 1416-1429 (2011)
64. Saab AM, Tundis R, Loizzo MR, Lampronti I, Borgatti M, Gambari R, Menichini F, Esseily F, Menichini F. Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 2011 Oct 21. [Epub ahead of print]
65. Fabbri E, Brognara E, Borgatti M, Lampronti I, Finotti A, Bianchi N, Sforza S, Tedeschi T, Manicardi A, Marchelli R, Corradini R, Gambari R. miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs. Epigenomics. 3:733-45 (2011).
66. A. M. Saab, I. Lampronti, A. Grandini, M. Borgatti, A. Finotti, G. Sacchetti, R. Gambari, A. Guerrini. Antiproliferative and Erythroid Differentiation Activities of Cedrus libani Seed Extracts against K562 Human Chronic Myelogenus Leukemia Cells. International Journal Of Pharmaceutical And Biological Archives 2: 1658-1662 (2011)
67. Saab A, Lampronti I, Finotti A, Borgatti M, Gambari R et al. In vitro evaluation of biological activity of Lebanese medicinal plant extracts against Herpes Simplex Virus type I. Minerva biotech. 24:117-21 (2012)
68. Saab AM, Lampronti I, Borgatti M, Finotti A, Harb F, Safi S, Gambari R. In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 26:2227-31 (2012).
69. Capretto L, Mazzitelli S, Brognara E, Lampronti I, Carugo D, Hill M, Zhang X, Gambari R, Nastruzzi C. Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia. Int J Nanomedicine. 7:307-24 (2012).
70. Fibach E, Prus E, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Finotti A, Lipucci di Paola M, Brognara E, Lampronti I, Borgatti M, Gambari R. Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients. Int J Mol Med. 29: 974-982 (2012).
71. Bianchi N, Zuccato C, Finotti A, Lampronti I, Borgatti M, Gambari R. Involvement of miRNA in erythroid differentiation. Epigenomics. 4:51-65 (2012).
72. Gambari R, Borgatti M, Lampronti I, Fabbri E, Brognara E, Bianchi N, Piccagli L, Yuen MC, Kan CW, Hau DK, Fong WF, Wong WY, Wong RS, Chui CH. Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells. International Immunopharmacology, 13:308-315 (2012).
73. Zuccato C, Breda L, Salvatori F, Breveglieri G, Gardenghi S, Bianchi N, Brognara E, Lampronti I, Borgatti M, Rivella S, Gambari R. A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction. Annals Of Hematology, 91:1201-13 (2012).
74. Finotti A, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi M, Mancini I, Cabrini G, Saviano M, Avitabile C, Romanelli A, Gambari R. Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: Recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene. Artif DNA PNA XNA. 3:97-296 (2012).
75. Dechecchi MC, Nicolis E, Mazzi P, Paroni M, Cioffi F, Tamanini A, Bezzerri V, Tebon M, Lampronti I, Huang S, Wiszniewski L, Scupoli M.T, Bragonzi A, Gambari R, Berton G, Cabrini G. (2012). Pharmacological Modulators of Sphingolipid Metabolism for the Treatment of Cystic Fibrosis Lung Inflammation. In: -. Cystic Fibrosis - Renewed Hopes Through Research. p. 439-452, Dinesh Sriramulu, ISBN: 9789535102878
76. Esseily F, El Ezzy M, Galy-Muhtasib H, Safi S, Esseily J, Lmapronti I, Saab A. The ethanol fraction from the stem of Berberis libanotica inhibits the viability of adult T cell leukemia. Minerva Biotech. 24: 29-33 (2012).
77. Saab AM, Dobmeier M, Koenig B, Fabri E, Finotti A, Borgatti M, Lampronti I, Bernardi F, Efferth T, Gambari R. Antiproliferative and erythroid differentiation of piperazine and triphenyl derivatives against k-562 human chronic myelogenous leukemia. Anticancer Res. 33(8):3027-32 (2013).
78. Salvador A, Brognara E, Vedaldi D, Castagliuolo I, Brun P, Zuccato C, Lampronti I, Gambari R. Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts. J Photochem Photobiol B. Apr 5;121:57-66 (2013).
79. Lampronti I, Borgatti M, Vertuani S, Manfredini S, Gambari R. Modulation of the expression of the pro-inflammatory IL-8 gene in cystic fibrosis cells by extracts deriving from olive mill waste water. eCAM (Evid based Complement Alternat Med.), Article ID 960603, 11 pages, (2013).
80. Saab AM, Gali-Muhtasib H, Maietti S, Grandini A, Rossi D, Lampronti I, Gallerani E, Gambari R. Comparative Antiproliferative Activities of Wood and Seeds Essential Oils of Juniperus oxycedrus L. against K562 Human Chronic Myelogenous Leukemia Cells. J Essential oil Res. (2013).
81. Fabbri E, Borgatti M, Montagner G, Bianchi N, Finotti A, Lampronti I, Bezzerri V, Dechecchi MC, Cabrini G, Gambari R. Expression of miR-93 and IL-8 During Pseudomonas aeruginosa Mediated Induction of Pro-Inflammatory Responses. Am J Respir Cell Mol Biol. 50:1144-55 (2014).
82. Loberto N, Tebon M, Lampronti I, Marchetti N, Aureli M, Bassi R, Giri MG, Bezzerri V, Lovato V, Cantù C, Munari S, Cheng SH, Cavazzini A, Gambari R, Sonnino S, Cabrini G, Dechecchi MC. GBA2-Encoded β-Glucosidase Activity Is Involved in the Inflammatory Response to Pseudomonas aeruginosa. PLoS One; 9:104763 (2014).
83. Bezzerri V, Avitabile C, Dechecchi MC, Lampronti I, Borgatti M, Montagner G, Cabrini G, Gambari R, Romanelli A. Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis. J. Pept. Sci. 20:822-30 (2014).
84. Montagner G, Gemmo C, Fabbri E, Manicardi A, Accardo I, Bianchi N, Finotti A, Breveglieri G, Salvatori F, Borgatti M, Lampronti I, Bresciani A, Altamura S, Corradini R, Gambari R. Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells. Int J Mol Med.;35:51-8 (2015).
85. Baldisserotto A, Vertuani S, Bino A, De Lucia D, Lampronti I, Milani R, Gambari R, Manfredini S. Design, synthesis and biological activity of a novel Rutin analogue with improved lipid soluble properties. Bioorg Med Chem;23:264-71 (2015).
86. Muresan XM, Cervellati F, Sticozzi C, Belmonte G, Chui CH, Lampronti I, Borgatti M, Gambari R, Valacchi G. The loss of cellular junctions in epithelial lung cells induced by cigarette smoke is attenuated by corilagin. Oxid Med Cell Longev; 631758 (2015).
87. Bianchi N, Chiarabelli C, Zuccato C, Lampronti I, Borgatti M, Amari G, Delcanale M, Chiavilli F, Prus E, Fibach E, Gambari R. Erythroid differentiation ability of butyric acid analogues: Identification of basal chemical structures of new inducers of foetal haemoglobin. Eur J Pharmacol;752:84-91 (2015).
88. Bianchi N, Finotti A, Ferracin M, Lampronti I, Zuccato C, Breveglieri G, Brognara E, Fabbri E, Borgatti M, Negrini M, Gambari R. Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells. PLoS One. 10:e0121567 (2015).
89. Marzaro G, Lampronti I, Borgatti M, Manzini P, Gambari R, Chilin A. Psoralen derivatives as inhibitors of NF-kB interaction: the critical role of the furan ring. Mol Divers. 2015 Apr 14.
90. Breveglieri G, Mancini I, Bianchi N, Lampronti I, Salvatori F, Fabbri E, Zuccato C, Cosenza MC, Montagner G, Borgatti M, Altruda F, Fagoonee S, Carandina G, Rubini M, Aiello V, Breda L, Rivella S, Gambari R, Finotti F. Generation and Characterization of a Transgenic Mouse Carrying a Functional Human 𝛽-Globin Gene with the IVSI-6 Thalassemia Mutation. BioMed Research International, Article ID 687635 (2015).
91. Milani R, Marcellini A, Montagner G, Baldisserotto A, Manfredini S, Gambari R, Lampronti I. Phloridzin derivatives inhibiting pro-inflammatory cytokine expression in human cystic fibrosis IB3-1 cells. Eur J Pharm Sciences; 78: 225-233 (2015).
92. Brognara E, Fabbri E, Montagner G, Gaspariello J, Manicardi A, Corradini R, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Lampronti I, Milani R, Dechecchi MC, Cabrini G, Gambari R. High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acid targeting miR-221 and miR-222. Int J Oncol; 48:1029-38 (2016).
93. Finotti A, Borgatti M, Bianchi N, Zuccato C, Lampronti I, Gambari G. Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations. Expert Opinion On Orphan Drugs (2016)
94. Bianchi N, Cosenza LC, Lampronti I, Finotti A, Breveglieri G, Zuccato C, Fabbri E, Marzaro G, Chilin A, De Angelis G, Borgatti M, Gallucci C, Alfieri C, Ribersani M, Isgrò A, Marziali M, Gaziev J, Morrone A, Sodani P, Lucarelli G, Gambari R, Paciaroni K. Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β(0)-Thalassemia Families with High Fetal Hemoglobin Levels. Mol Diagn Ther; 20:161-73 (2016)
95. Fabbri E, Montagner G, Bianchi N, Finotti A, Borgatti M, Lampronti I, Cabrini G, Gambari R. MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells. Oncol Rep; 35: 2866-72 (2016)
96. Bergamini P, Marvelli L, Ferretti V, Gemmo C, Gambari R, Hushcha Y, Lampronti I. Bis(dimethylsulfoxide)carbonateplatinum(II), a new synthon for a low-impact, versatile synthetic route to anticancer Pt carboxylates. Dalton; 45: 10752-10760 (2016).
97. Prandini P, De Logu S, Fusi C, Provezza L, Nassini R, Montagner G, Materazzi S, Munari S, Gilioli E, Bezzerri V, Finotti A, Lampronti I, Tamarini A, Dechecchi MC, Lippi G, Riberio CM, Rimessi A, Pinton P, Gambari R, Geppetti P, Cabrini G, American Journal of Respiratory Cell and Molecular Biology; 55:645-656 (2016).
98. Brunetti J, Roscia G, Lampronti I, Gambari R, Quercini L, Falciani C, Bracci L, Pini A. Immunomodulatory and anti-inflammatory activity in vitro and in vivo of a novel antimicrobial candidate. J Biol Chem. (2016)
99. Cosenza LC, Breda L, Breveglieri G, Zuccato C, Finotti A, Lampronti I, Borgatti M, Chiavilli F, Gamberini MR, Satta S, Manunza L, De Martis FR, Moi P, Rivella S, Gambari R, Bianchi N. J Transl Med. 2;14:255 (2016)
101. Montagner G, Bezzerri V, Cabrini G, Fabbri E, Borgatti M, Lampronti I, Finotti A, Nielsen PE, Gambari R. An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system. 16: 30671-7 (2017).
100. Lampronti I, Finotti A, Bianchi N, Borgatti M, Gambari R. Natural substances in the treatment of cystic fibrosis, Clinical Immunology Endocrine & Metabolic Drugs. Editor: Bentham Science, 3: 130-139 (2016), DOI: 10.2174/2212707004666170504152657.
101. Lampronti I, Dechecchi MC, Rimessi A, Bezzerri V, Nicolis A, Guerrini A, Tacchini M, Tamanini A, Munari S, D'Aversa E, Santangelo A, Lippi G, Sacchetti G, Pinton P, Gambari R, Agostini M, Cabrini G. Betasitosterol reduces the expression of chemotactic cytokine genes in cystic fibrosis bronchial epithelial cells. Frontiers in Pharmacology 8:236 (2017).
102. Milani R, Brognara E, Fabbri E, Finotti A, Borgatti M, Lampronti I, Marzaro G, Chilin A, Lee KK, Kok SH, Chui CH, Gambari R. Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line. Oncol Res. (2017)
103. Saab MA, Gambari R, Sacchetti G, Guerrini A, Lampronti I, Tacchini M, El Samrani A, Medawar S, Makhlouf H, Tannoury M, Abboud J, Diab-Assaf M, Kiìijoa A, Tundis R, Aoun J, Efferth T. Phytochemical and pharmacological properties of essential oils from Cedrus plant spacies. Nat Prod Res, 1-13 (2017)
104. Mesiano G, Zini R, Montagner G, Bianchi N, Manfredini R, Chillemi A, Aglietta M, Grignani G, Lampronti I, Fiorino E, Malavasi F, Sangiolo D, Gambari R, Ferrari D. Analytic and Dynamic Secretory Profile of Patient-Derived Cytokine-Induced Killer Cells. Mol Med, 23 (2017)
105. Breveglieri G, Bianchi N, Cosenza LC, Gamberini MR, Chiavilli F, Zuccato C, Montagner G, Borgatti M, Lampronti I, Finotti A, Gambari R. An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production. BMC Med Genet,18:93 (2017)
106. Lampronti I, Manzione MG, Sacchetti G, Ferrari D, Spisani S, Bezzerri V, Finotti A, Borgatti M, Dechecchi MC, Miolo G, Marzaro G, Cabrini G, Gambari R, Chilin A. Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells. Mediators Inflamm. doi: 10.1155/2017/2389487 (2017)
107. Finotti A, Gasparello J, Lampronti I, Cosenza LC, Maconi G, Matarese V, Gentili V, Di Luca D, Gambari R, Caselli M. PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis. BMJ Open Gastroenterol. 4(1):e000172. (2017)
108. Fabbri E, Tamanini A, Jakova T, Gasparello J, Manicardi A, Corradini R, Sabbioni G, Finotti A, Borgatti M, Lampronti I, Munari S, Dechecchi MC, Cabrini G, Gambari R. A Peptide Nucleic Acid against MicroRNA miR-145-5p Enha nces the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells. Molecules, 23, 71 (2017)
109. Lampronti I, Finotti A, Bianchi N, Borgatti M, Gambari R. Natural Substances in the Treatment of Cystic Fibrosis. Clinical Immunology, Endocrine and metabolic drugs. Review (2017).
110. Ferretti V, Bergamini P, Marvelli L, Gemmo C, Gambari R, Lampronti I. Synthesis and characterization of Pt complexes containing dichloroacetate (DCA), designed for dual anticancer action. Inorganica Chimica Acta, 470: 119-127, 2018.
111. Lamberti N, Finotti A, Gasparello J, Lampronti I, Zambon C, Cosenza LC, Fabbri E, Bianchi N, Dalla Corte F, Govoni M, Reverberi R, Gambari R, Manfredini F. Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports. Intern Emerg Med. 2018 Jun;13(4):517-526.
112. Baldisserotto A, Buso P, Radice M, Dissette V, Lampronti I, Gambari R, Manfredini S, Vertuani S. Moringa Oleifera Leaf Extracts as Multifunctional Ingredients for “Natural and Organic” Sunscreens and Photoprotective Preparations. Molecules 23 (3), 664 (2018)
113. Marzaro G, Lampronti I, D’Aversa E, Sacchetti G, Miolo G, Vaccarin C, Cabrini G, Dechecchi MC, Gambari R, Chilin A. Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). Eur J Med Chem, 151: 285-293 (2018).
114. Laselva O, Marzaro G, Vaccarin C, Lampronti I, Tamanini A, Lippi G, Gambari R, Cabrini G, Bear CE, Chilin A, Dechecchi MC. Molecular mechanism of action of Trimethylangelicin derivatives as CFTR modulators. Frontiers in Pharmacology, section Pharmacology of Ion Channels and Channelopathies. 9: article 719 (2018).
115. Salvatori F, Pappadà M, Breveglieri G, D'Aversa E, Finotti A, Lampronti I, Gambari R, Borgatti M. UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation. BMC Biotechnol 15;18:28 (2018).
116. Anna Baldisserrotto; Monica Demurtas; Ilaria Lampronti; Davide Moi; Gianfranco Balboni; Silvia Verturani; Stefano Manfredini; Valentina Onnis. Benzofuran Hydrazones as potential scaffold in the development of multifunctional drugs: synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity, European Journal of Medicinal Chemistry, 156:118-125 (2018)
117. Scattolin T, Caligiuri I, Canovese L, Demitri N, Gambari R, Lampronti I, Rizzolio F, Santo C, Visentin F. Synthesis of new allyl palladium complexes bearing purine-based NHC ligands with antiproliferative and proapoptotic activity on human ovarian cancer cell lines. Dalton Transaction. 47(38):13616-13630 (2018).
118. Bino A, Vicentini CB, Vertuani S, Lampronti I, Gambari R, Durini E, Manfredini S, Baldisserotto A. Novel Lipidized Derivatives of the Bioflavonoid Hesperidin: Dermatological, Cosmetic and Chemopreventive Applications. Cosmetics. Accepted for publication (2018).
119. Finotti A, Fabbri E, Lampronti I, Gasparello J, Borgatti M, Gambari R. MicroRNAs and Long Non-coding RNAs in Genetic Diseases. Mol Diagn Ther. 23: 155-171 (2019).
120. Demurtas M, Baldisserotto A, Lampronti I, Moi D, Balboni G, Pacifico S,Verturani S, Manfredini S, Omnis V, Indole derivatives as multifunctional drugs: synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones. Bioorganic Chemistry. 85:568-576 (2019)
121. Scattolin T, Bergamini P, Caligiuri I, Canovese L, Demitri N, Giust S, Gambari R, Lampronti I, Rizzolio F, Visentin F. Palladacyclopentadienyl complexes bearing purine-based NHCs: a new class of promising antiproliferative agents against human ovarian cancer. Applied Organometallic Chemistry. accepted for publication (2019).
122. Scattolin T, Pangerc N, Lampronti I, Tupini C, Gambari R, Marvelli L, Rizzolio F, Demitri N, Canovese L. Palladium (0) olefin complexes bearing purine-based N-heterocyclic carbenes and 1,3,5-triaza-7-phosphaadamantane (PTA): Synthesis, characterization and antiproliferative activity toward human ovarian cancer cell lines. J Organometallic Chemistry, Accepted for publication (2019).
123. Marvelli L, Ferretti V, Bertolasi V, Lampronti I, Gambari R, Trapella C, Turrin G, Bonotto F, Moriello A, Bergamini P. A new amido-phosphine of dichloroacetic acid as an active ligand for metals of pharmaceutical interest. Synthesis, characterization and tests of antiproliferative and pro-apoptotic activity. J Inorg Biochem. 199:110787. doi: 10.1016 (2019).
124. De Fenza M, D'Alonzo D, Esposito A, Munari S, Loberto N, Santangelo A, Lampronti I, Tamanini A, Rossi A, Ranucci S, De Fino I, Bragonzi A, Aureli M, Bassi R, Tironi M, Lippi G, Gambari R, Cabrini G, Palumbo G, Dechecchi MC, Guaragna A. Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease. Eur J Med Chem. 175:63-71 (2019).
125. Gasparello J, Lamberti N, Papi C, Lampronti I, Cosenza LC, Fabbri E, Bianchi N, Zambon C, Dalla Corte F, Govoni M, Reverberi R, Manfredini F, Gambari R, Finotti A. Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport. Transfusion. 59:2709-2721 (2019).
126.Milani R, Brognara E, Fabbri E, Manicardi A, Corradini R, Finotti A, Gasparello J, Borgatti M, Cosenza LC, Lampronti I, Dechecchi MC, Cabrini G, Gambari R. Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells. Int J Oncol. 55:59-68 (2019).
127. Gemmo C, Breveglieri G, Marzaro G, Lampronti I, Cosenza LC, Gasparello J, Zuccato C, Fabbri E, Borgatti M, Chilin A, Finotti A, Gambari R. Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia. Anal Bioanal Chem. doi: 10.1007/s00216-019-01987-9 (2019)
