Pubblicazioni

**Selezione pubblicazioni in extenso su riviste internazionali**

**autore responsabile del coordinamento della ricerca pubblicata oppure autore a cui indirizzare la corrispondenza

*autore co-responsabile del coordinamento della ricerca pubblicata

Cabrini G**.

Editorial: CFTR Modulators and Reduction of Airway Inflammation in Cystic Fibrosis: How Much is Enough?

Curr Med Chem. 2022 Oct 14. Epub ahead of print.

Vaccarin C, Gabbia D, Franceschinis E, De Martin S, Roverso M, Bogialli S, Sacchetti G, Tupini C, Lampronti I, Gambari R, Cabrini G, Dechecchi MC, Tamanini A, Marzaro G, Chilin A. Improved Trimethylangelicin Analogs for Cystic Fibrosis: Design, Synthesis and Preliminary Screening.

Int J Mol Sci. 2022;23:11528.

Papi C, Gasparello J, Zurlo M, Manicardi A, Corradini R, Cabrini G, Gambari R, Finotti A. Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene.

Int J Mol Sci. 2022;23:9348.

Rossi A, Bragonzi A, Medede M, De Fino I, Lippi G, Prosdocimi M, Tamanini A, Cabrini G*, Dechecchi MC. β-sitosterol ameliorates inflammation and Pseudomonas aeruginosa lung infection in a mouse model.

J Cyst Fibros. 2022:S1569-1993(22)00642-7.

Catelan S, Olioso D, Santangelo A, Scapoli C, Tamanini A, Pinna G, Sala F, Lippi G, Nicolato A, Cabrini G*, Dechecchi MC. miRNAs in Serum Exosomes for Differential Diagnosis of Brain Metastases.

Cancers (Basel). 2022;14:3493.

Cabrini G**, Rimessi A, Borgatti M, Pinton P, Gambari R. Overview of CF lung pathophysiology.

Curr Opin Pharmacol. 2022;64:102214.

Ribeiro CMP, McElvaney NG, Cabrini G**.

Editorial: Novel Anti-Inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies.

Front Pharmacol. 2021;12:794854.

Olioso D, Caccese M, Santangelo A, Lippi G, Zagonel V, Cabrini G*, Lombardi G, Dechecchi MC. Serum Exosomal microRNA-21, 222 and 124-3p as Noninvasive Predictive Biomarkers in Newly Diagnosed High-Grade Gliomas: A Prospective Study. Cancers (Basel). 2021;13:3006.

Tamanini A, Fabbri E, Jakova T, Gasparello J, Manicardi A, Corradini R, Finotti A, Borgatti M, Lampronti I, Munari S, Dechecchi MC, Cabrini G, Gambari R. A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1.

Biomedicines. 2021;9:117.

Fabbri E, Tamanini A, Jakova T, Gasparello J, Manicardi A, Corradini R, Finotti A, Borgatti M, Lampronti I, Munari S, Dechecchi MC, Cabrini G, Gambari R. Treatment of human airway epithelial Calu-3 cells with a peptide-nucleic acid (PNA) targeting the microRNA miR-101-3p is associated with increased expression of the cystic fibrosis Transmembrane Conductance Regulator () gene.

Eur J Med Chem. 2021; 209:112876

Cabrini G**, Rimessi A, Borgatti M, Lampronti I, Finotti A, Pinton P, Gambari R. Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis. Front Immunol. 2020 Aug 4;11:1438.

Santangelo A, Rossato M, Lombardi G, Benfatto S, Lavezzari D, De Salvo GL, Indraccolo S, Dechecchi MC, Prandini P, Gambari R, Scapoli C, Di Gennaro G, Caccese M, Eoli M, Rudà R, Brandes AA, Ibrahim T, Rizzato S, Lolli I, Lippi G, Delledonne M, Zagonel V, Cabrini G**. A Molecular Signature associated with prolonged survival in Glioblastoma patients treated with Regorafenib.NeuroOncol. 2020 Jul 14: Epub ahead of print.

Mancini G, Loberto N, Olioso D, Dechecchi MC, Cabrini G, Mauri L, Bassi R, Schiumarini D, Chiricozzi E, Lippi G, Pesce E, Sonnino S, Pedemonte N, Tamanini A, Aureli M. GM1 as Adjuvant of Innovative Therapies for Cystic Fibrosis Disease. Int J Mol Sci. 2020;21(12):4486.

Rimessi A, Pozzato C, Carparelli L, Rossi A, Ranucci S, De Fino I, Cigana C,Talarico AWieckowski MR, Ribeiro CMP, Trapella C, Rossi G, Cabrini G, Bragonzi A, Pinton P. Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis. Sci Adv. 2020;6:eaax9093.

Sultan S, Rozzi A, Gasparello J, Manicardi A, Corradini R, Papi C, Finotti A, Lampronti I, Reali E, Cabrini G, Gambari R, Borgatti M. A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (<i>CFTR</i>) mRNA Enhances CFTR Expression in Calu-3 Cells. Molecules. 2020;25(7):1677.

Milani R, Brognara E, Fabbri E, Manicardi A, Corradini R, Finotti A, Gasparello J, Borgatti M, Cosenza LC, Lampronti I, Dechecchi MC, Cabrini G, Gambari R. Targeting miR-155-5p and miR-221-3p by peptide nucleic acids induces caspase-3 activation and apoptosis in temozolomide-resistant T98G glioma cells. Int J Oncol. 2019;55:59-68.

De Fenza M, D'Alonzo D, Esposito A, Munari S, Loberto N, Santangelo A, Lampronti I, Tamanini A, Rossi A, Ranucci S, De Fino I, Bragonzi A, Aureli M, Bassi R, Tironi M, Lippi G, Gambari R, Cabrini G, Palumbo G, Dechecchi MC, Guaragna A. Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease. Eur J Med Chem. 2019;175:63-71.

Finotti A, Gasparello J, Fabbri E, Tamanini A, Corradini R, Dechecchi MC, Cabrini G, Gambari R. Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p. Am J Respir Crit Care Med. 2019;199:1443-1444.

Cabrini G.** Innovative Therapies for Cystic Fibrosis: The Road from Treatment to Cure. Mol Diagn Ther. 2018 Nov 26.

Dechecchi MC, Tamanini A, Cabrini G**. Molecular basis of cystic fibrosis: from bench to bedside. Ann Transl Med. 2018 Sep;6(17):334.

Laselva O, Marzaro G, Vaccarin C, Lampronti I, Tamanini A, Lippi G, Gambari R, Cabrini G, Bear CE, Chilin A, Dechecchi MC. Molecular Mechanism of Action of Trimethylangelicin Derivatives as CFTR Modulators. Front Pharmacol. 2018 Jul 4;9:719.

Rimessi A, Bezzerri V, Salvatori F, Tamanini A, Nigro F, Dechecchi MC, Santangelo A, Prandini P, Munari S, Provezza L, Garreau de Loubresse N, Muller J, Ribeiro CMP, Lippi G, Gambari R, Pinton P, Cabrini G**. PLCB3 Loss-of-function Reduces P. aeruginosa-dependent IL-8 Release in Cystic Fibrosis. Am J Respir Cell Mol Biol. 2018;59:428-436.

Marzaro G, Lampronti I, D'Aversa E, Sacchetti G, Miolo G, Vaccarin C, Cabrini G, Dechecchi MC, Gambari R, Chilin A. Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB). Eur J Med Chem. 2018;151:285-293.

Schiumarini D, Loberto N, Mancini G, Bassi R, Giussani P, Chiricozzi E, Samarani M, Munari S, Tamanini A, Cabrini G, Lippi G, Dechecchi MC, Sonnino S, Aureli M. Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells. Mediators Inflamm. 2017;2017:1730245.

Fabbri E, Tamanini A, Jakova T, Gasparello J, Manicardi A, Corradini R, Sabbioni G, Finotti A, Borgatti M, Lampronti I, Munari S, Dechecchi MC, Cabrini G, Gambari R. A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells. Molecules. 2017;23: E71.

Lampronti I, Manzione MG, Sacchetti G, Ferrari D, Spisani S, Bezzerri V, Finotti A, Borgatti M, Dechecchi MC, Miolo G, Marzaro G, Cabrini G, Gambari R, Chilin A. Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells. Mediators Inflamm. 2017;2017:2389487.

Santangelo A, Imbrucè P, Gardenghi B, Belli L, Agushi R, Tamanini A, Munari S, Bossi AM, Scambi I, Benati D, Mariotti R, Di Gennaro G, Sbarbati A, Eccher A, Ricciardi GK, Ciceri EM, Sala F, Pinna G, Lippi G, Cabrini G*, Dechecchi MC. A microRNA signature from serum exosomes of patients with glioma as complementary diagnostic biomarker. J Neurooncol. 2018;136:51-62.

Santangelo A, Tamanini A, Cabrini G*, Dechecchi MC. Circulating microRNAs as emerging non-invasive biomarkers for gliomas. Ann Transl Med. 2017;5:277. Review.

Lampronti I, Dechecchi MC, Rimessi A, Bezzerri V, Nicolis E, Guerrini A, Tacchini M, Tamanini A, Munari S, D'Aversa E, Santangelo A, Lippi G, Sacchetti G, Pinton P, Gambari R, Agostini M, Cabrini G**. β-Sitosterol Reduces the Expression of Chemotactic Cytokine Genes in Cystic Fibrosis Bronchial Epithelial Cells. Front Pharmacol. 2017;8:236.

Brunelli M, Eccher A, Cima L, Trippini T, Pedron S, Chilosi M, Barbareschi M, Scarpa A, Pinna G, Cabrini G, Pilotto S, Carbognin L, Bria E, Tortora G, Schiavo N, Meglio M, Sava T, Belli L, Martignoni G, Ghimenton C. Next-generation repeat-free FISH probes for DNA amplification in glioblastoma in vivo: Improving patient selection to MDM2-targeted inhibitors.Cancer Genet. 2017;210:28-33.

Montagner G, Bezzerri V, Cabrini G, Fabbri E, Borgatti M, Lampronti I, Finotti A, Nielsen PE, Gambari R. An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system. Int J Biol Macromol. 2017;99:492-498.

Prandini P, De Logu F, Fusi C, Provezza L, Nassini R, Montagner G, Materazzi S, Munari S, Gilioli E, Bezzerri V, Finotti A, Lampronti I, Tamanini A, Dechecchi MC, Lippi G, Ribeiro CM, Rimessi A, Pinton P, Gambari R, Geppetti P, Cabrini G**. Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis. Am J Respir Cell Mol Biol. 2016;55:645-656.

Aureli M, Schiumarini D, Loberto N, Bassi R, Tamanini A, Mancini G, Tironi M, Munari S, Cabrini G, Dechecchi MC, Sonnino S. Unravelling the role of sphingolipids in cystic fibrosis lung disease.Chem Phys Lipids. 2016 ;200:94-103.

Brognara E, Fabbri E, Montagner G, Gasparello J, Manicardi A, Corradini R, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Lampronti I, Milani R, Dechecchi MC, Cabrini G, Gambari R. High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222. Int J Oncol. 2016;48:1029-38.

Cigana C, Lorè NI, Riva C, De Fino I, Spagnuolo L, Sipione B, Rossi G, Nonis A, Cabrini G, Bragonzi A. Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections. Sci Rep. 2016;6:21465.

Fabbri E, Montagner G, Bianchi N, Finotti A, Borgatti M, Lampronti I, Cabrini G, Gambari R. MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells. Oncol Rep. 2016;35:2866-72.

Khalil S, Fabbri E, Santangelo A, Bezzerri V, Cantù C, Di Gennaro G, Finotti A, Ghimenton C, Eccher A, Dechecchi M, Scarpa A, Hirshman B, Chen C, Ferracin M, Negrini M, Gambari R, Cabrini G**. miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma. Oncotarget. 2016;7:28195-206.

Fabbri E, Brognara E, Montagner G, Ghimenton C, Eccher A, Cantù C, Khalil S, Bezzerri V, Provezza L, Bianchi N, Finotti A, Borgatti M, Moretto G, Chilosi M, Cabrini G**, Gambari R. Regulation of IL-8 gene expression in gliomas by microRNA miR-93. BMC Cancer. 2015;15:661.

Cabrini G**, Fabbri E, Lo Nigro C, Dechecchi MC, Gambari R. Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review). Int J Oncol. 2015;47:417-28.

Rimessi A, Bezzerri V, Patergnani S, Marchi S, Cabrini G*, Pinton P. Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomona aeruginosa-driven inflammatory response in cystic fibrosis. Nat Commun. 2015 Feb 4;6:6201.

Bezzerri V, Avitabile C, Dechecchi MC, Lampronti I, Borgatti M, Montagner G, Cabrini G, Gambari R, Romanelli A. Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis. J Pept Sci. 2014;20:822-30.

Loberto N, Tebon M, Lampronti I, Marchetti N, Aureli M, Bassi R, Giri MG, Bezzerri V, Lovato V, Cantù C, Munari S, Cheng SH, Cavazzini A, Gambari R, Sonnino S, Cabrini G, Dechecchi MC. GBA2-encoded β-glucosidase activity is involved in the inflammatory response to Pseudomonas aeruginosa. PLoS One. 2014;9:e104763.

Favia M, Mancini MT, Bezzerri V, Guerra L, Laselva O, Abbattiscianni AC, Debellis L, Reshkin SJ, Gambari R, Cabrini G*, Casavola V. Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells. Am J Physiol Lung Cell Mol Physiol. 2014;307:L48-61.

Rubino R, Bezzerri V, Favia M, Facchini M, Tebon M, Singh AK, Riederer B, Seidler U, Iannucci A, Bragonzi A, Cabrini G, Reshkin SJ, Tamanini A. Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1. Pflugers Arch. (Eur J Physiol) 2014;466:2269-78

Brognara E, Fabbri E, Bazzoli E, Montagner G, Ghimenton C, Eccher A, Cantù C, Manicardi A, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Corradini R, Bezzerri V, Cabrini G, Gambari R. Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221. J Neurooncol. 2014;118:19-28.

Fabbri E, Borgatti M, Montagner G, Bianchi N, Finotti A, Lampronti I, Bezzerr V, Dechecchi MC, Cabrini G, Gambari R. Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses. Am J Respir Cell Mol Biol. 2014;50:1144-55.

Finotti A, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi M, Mancini I, Cabrini G, Saviano M, Avitabile C, Romanelli A, Gambari R. Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene. Artif DNA PNA XNA. 2012;3:97-296.

Galli F, Battistoni A, Gambari R, Pompella A, Bragonzi A, Pilolli F, Iuliano L, Piroddi M, Dechecchi MC, Cabrini G**; Working Group on Inflammation in Cystic Fibrosis. Oxidative stress and antioxidant therapy in cystic fibrosis. Biochim Biophys Acta. 2012;1822:690-713.

Bezzerri V, Borgatti M, Finotti A, Tamanini A, Gambari R, Cabrini G**. Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells. J Immunol. 2011;187:6069-81.

Dechecchi MC, Nicolis E, Mazzi P, Cioffi F, Bezzerri V, Lampronti I, Huang S, Wiszniewski L, Gambari R, Scupoli MT, Berton G, Cabrini G**. Modulators of sphingolipid metabolism reduce lung inflammation. Am J Respir Cell Mol Biol. 2011;45:825-33.

Bezzerri V, d'Adamo P, Rimessi A, Lanzara C, Crovella S, Nicolis E, Tamanini A, Athanasakis E, Tebon M, Bisoffi G, Drumm ML, Knowles MR, Pinton P, Gasparini P, Berton G, Cabrini G**. Phospholipase C-{beta}3 Is a Key Modulator of IL-8 Expression in Cystic Fibrosis Bronchial Epithelial Cells. J Immunol. 186, 4946-58, 2011.

Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G*/**, Gambari R. Trimethylangelicin Reduces IL-8 Transcription and Potentiates CFTR Function. Am J Physiol Lung Cell Mol Physiol. 300, L380-90, 2011

Crovella S, Segat L, Amato A, Athanasakis E, Bezzerri V, Braggion C, Casciaro R, Castaldo G, Colombo C, Covone AE, De Rose V, Gagliardini R, Lanzara C, Minicucci L, Morgutti M, Nicolis E, Pardo F, Quattrucci S, Raia V, Ravazzolo R, Seia M, Stanzial V, Termini L, Zazzeron L, Cabrini G, Gasparini P. A polymorphism in the 5' UTR of the DEFB1 gene is associated with the lung phenotype in F508del homozygous Italian cystic fibrosis patients. Clin Chem Lab Med. 49, 49-54, 2011

Piccagli L, Borgatti M, Nicolis E, Bianchi N, Mancini I, Lampronti I, Vevaldi D, Dall'Acqua F, Cabrini G, Gambari R. Virtual screening against nuclear factor kB (NF-kB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-kB dependent biological functions involved in cystic fibrosis. Bioorg Med Chem. 18, 8341-9, 2010

Cabrini G, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Tamanini A, Lampronti I, Piccagli L, Bianchi N, Borgatti M, Gambari R. Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds. Curr Med Chem. 17, 4392-404, 2010

Gambari R, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Tamanini A, Cabrini G. Decoy oligodeoxyribonucleotides and peptide nucleic acids-DNA chimeras targeting nuclear factor kappa-B: inhibition of IL-8 gene expression in cystic fibrosis cells infected with Pseudomonas aeruginosa. Biochem Pharmacol. 80, 1887-94, 2010

Piccagli L, Fabbri E, Borgatti M, Bianchi N, Bezzerri V, Mancini I, Nicolis E, Dechecchi CM, Lampronti I, Cabrini G, Gambari R. Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes. ChemMedChem. 4, 2024-33, 2009

Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G**. Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen. Int Immunopharmacol. 9, 1411-22, 2009

Copreni E, Nicolis E, Tamanini A, Bezzerri V, Castellani S, Palmieri L, Giri MG, Vella A, Colombatti M, Rizzotti P, Conese M, Cabrini G**. Late generation lentiviral vectors: evaluation of inflammatory potential in human airway epithelial cells. Virus Res. 144, 8-17, 2009.

Dechecchi MC, Nicolis E, Norez C, Bezzerri V, Borgatti M, Mancini I, Rizzotti P, Ribeiro CM, Gambari R, Becq F, Cabrini G**. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 7, 555-65, 2008

Piccagli L, Fabbri E, Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Cabrini G, Gambari R. Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression. BMC Struct Biol. 8, 38, 2008

Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bianchi N, Bezzerri V, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G**. Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells. Int Immunopharmacol. 8, 1672-80, 2008

Norez C, Pasetto M, Dechecchi MC, Barison E, Anselmi C, Tamanini A, Quiri F, Cattel L, Rizzotti P, Dosio F, Cabrini G*, Colombatti M. Chemical conjugation of DeltaF508-CFTR corrector deoxyspergualin to transporter human serum albumin enhances its ability to rescue Cl- channel functions. Am J Physiol Lung Cell Mol Physiol. 295, L336-47, 2008

Bezzerri V, Borgatti M, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Rizzotti P, Gambari R, Cabrini G**. Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells. Am J Respir Cell Mol Biol. 39, 86-96, 2008

Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily. Biochem Biophys Res Commun. 357, 977-83, 2007

Dechecchi MC, Nicolis E, Bezzerri V, Vella A, Colombatti M, Assael BM, Mettey Y, Borgatti M, Mancini I, Gambari R, Becq F, Cabrini G**. MPB-07 Reduces the Inflammatory Response to Pseudomonas aeruginosa in Cystic Fibrosis Bronchial Cells. Am J Respir Cell Mol Biol. 36, 615-624, 2007

Tamanini A, Nicolis E, Bonizzato A, Bezzerri V, Melotti P, Assael BM, Cabrini G**. Interaction of adenovirus type 5 fiber with the coxsackievirus and adenovirus receptor activates inflammatory response in human respiratory cells. J Virol. 80, 11241-54, 2006

Cabrini G**, Falzoni S, Forchap SL, Pellegatti P, Balboni A, Agostini P, Cuneo A, Castoldi G, Baricordi OR, Di Virgilio F. An His-155 to Tyr Polymorphism Confers Gain-of-function to the Human P2X7 Receptor of Human Leukemic Lymphocytes J Immunol 175, 82-89, 2005

Tamanini A, Rolfini R, Nicolis E, Melotti P, Cabrini G**. MAP Kinases and NF-kB collaborate to induce ICAM-1 gene expression in the early phase of adenovirus infection. Virology 307, 228-242, 2003

Cabrini G**, Zanolla L. Cystic fibrosis conductance regulator and lung clearance of Pseudomonas aeruginosa. J Clin Invest, eLetter to the Editor (www.jci.org), in reference to Worlizsch D. et al. J Clin Invest 109, 317-325, 2002

Zegarra-Moran O, Romio L, Folli C, Caci E, Becq F, Vierfond J.-M, Mettey Y, Cabrini G, Fanen P, Galietta LJV. Correction of G551D-CFTR transport defect by genistein in polarized respiratory monolayers. Brit J Pharmacol 137, 504-512, 2002

Campello S, Tombola F, Cabrini G, Zoratti M. The vacuolating toxin of Helicobacter pylori mimicks the CFTR-mediated chloride conductance. FEBS Lett 532, 237-240, 2002

Galietta LJV, Pagesy P, Folli C, Caci E, Romio L, Costes B, Nicolis E, Cabrini G, Goossens M, Ravazzolo R, Zegarra-Moran O. IL-4 is a potent modulator of ion transport in the human bronchial epithelium. J Immunol 168, 839-845, 2002

Melotti P, Nicolis E, Tamanini A, Rolfini R, Pavirani A, and Cabrini G**. Activation of NF-kB mediates ICAM-1 induction in respiratory cells exposed to an adenovirus-derived vector. Gene Ther 8, 1436-1442, 2001

Dechecchi MC, Melotti P, Bonizzato A, Santacatterina M, Chilosi M, Cabrini G**. Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5. J Virol 75, 8772-8780, 2001

Lerondel S, Le Pape A, Sené C, Faure L, Bernard S, Diot P, Nicolis E, Mehtali M, Lusky M, Cabrini G, Pavirani A. Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy. Hum Gene Ther 12, 1-11, 2001

Dechecchi MC, Tamanini A, Bonizzato A, Cabrini G**. Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2 – host cell interactions. Virology 268, 382-390, 2000

Nicolis E, Melotti P, Tamanini A, Lusky M, Mehtali M, Pavirani A, Cabrini G**. Quantitative detection of CFTR mRNA in gene transfer studies in human, murine and simian respiratory tissues in vitro and in vivo. Gene Ther Mol Biol 4, 221-232, 1999

Nicolis E, Tamanini A, Melotti P, Rolfini R, Berton G, Cassatella MA, Bout A, Pavirani A, Cabrini G**. ICAM-1 induction in respiratory cells exposed to a replication-deficient recombinant adenovirus in vitro and in vivo. Gene Ther 5: 131-136, 1998

Rotoli BM, Bussolati O, Dall' Asta V, Hoffman EK, Cabrini G, and Gazzola GC. CFTR expression in C127 cells is associated with enhanced cell shrinkage and ATP extrusion in Cl-free medium. Biophys Res Comm 227, 755-761, 1996

Renier M, Tamanini A, Nicolis E, Rolfini R, Imler J-L, Pavirani A, and Cabrini G**. Use of a membrane potential-sensitive probe to assess biological expression of the cystic fibrosis transmembrane conductance regulator. Hum Gene Ther 6, 1275-1233, 1995

Bonizzato A, Bisceglia L, Marigo C, Nicolis E, Bombieri C, Castellani C, Borgo G, Zelante L, Mastella G, Cabrini G, Gasparini P, Pignatti PF. Analysis of the complete coding region of the CFTR gene in a cohort of CF patients from North-Eastern Italy: identification of 90 % of mutations. Hum Genet 95, 397-402, 1995

Russo MP, Romeo G, Devoto M, Barbujani G, Cabrini G, Giunta A, D'Alcamo E, Leoni G, Sangiuolo F, Magnani C, Cremonesi L, Ferrari M. Analysis of linkage disequilibrium between different cystic fibrosis mutations and three intragenic microsatellites in the italian population. Hum Mutat 5, 23-27, 1995

Rotoli BM, Bussolati O, Sironi M, Cabrini G, Gazzola GC. CFTR protein is involved in the efflux of neutral aminoacids. Biochem Biophys Res Comm 204, 653-658, 1994

Laudanna C, Constantin G, Baron P, Scarpini E, Scarlato G, Cabrini G, Dechecchi C, Rossi F, Cassatella M, Berton G. Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha, and interleukin-8 mRNA in human neutrophils. J Biol Chem 269, 4021-4026, 1994

Rolfini R, Cabrini G**. Nonsense mutation R1162X of the cystic fibrosis transmembrane conductance regulator gene does not reduce messenger RNA expression in nasal epithelial tissue. J Clin Invest 92, 2683-2687, 1993

Dechecchi MC, Tamanini A, Berton G, Cabrini G**. Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene. J Biol Chem 268, 11321-11325, 1993

Melo CA, Serra C, Stoyanova V, Aguzzoli C, Faraguna D, Tamanini A, Berton G, Cabrini G, Baralle F. Alternative splicing of a previously unidentified CFTR exon introduces an in-frame stop codon 5' of the R region. FEBS Lett 329, 159-162, 1993

Gasparini P, Marigo C, Bisceglia G, Nicolis E, Zelante L, Bombieri C, Borgo G, Pignatti PF, Cabrini G. Screening of 62 mutations in a cohort of cystic fibrosis patients from North Eastern Italy: their incidence and clinical features of defined genotypes. Hum Mut 2, 389-394, 1993

Papini E, Cabrini G, Montecucco C. The sensitivity of cystic fibrosis cells to diphteria toxin. Toxicon 31, 359-362, 1993

Dechecchi MC, Rolfini R, Tamanini A, Gamberi C, Berton G, Cabrini G**. Effect of modulation of protein kinase C on the cAMP-dependent chloride conductance in T84 cells. FEBS Lett 311, 25-28, 1992

Placchi P, Lombardo R, Tamanini A, Brusa P, Berton G, Cabrini G**. cAMP-dependent protein kinase inhibits the chloride conductance in apical membrane vesicles of human placenta. J Membrane Biol 119, 25-32, 1991

Tamanini A, Berton G, Cabrini G**. Adenosine 3':5'-monophosphate-dependent protein kinase from human placenta: characterization of the catalytic subunit. Enzyme 45, 97-108, 1991

Squassoni E., Cabrini G., Berton G. cAMP dependent chloride conductance is not different in cystic fibrosis fibroblasts. Life Sci 46, 1265-70, 1990

Dechecchi MC, Cabrini G**. Chloride conductance in membrane vesicles from human placenta using a fluorescent probe. Implications for cystic fibrosis. Biochim Biophys Acta 945, 113-120, 1988

Dechecchi MC, Girella E, Cabrini G, Berton G. The Km of NADH dehydrogenase in mitochondria of cystic fibrosis fibroblast cell. Enzyme 40, 45-50, 1988

Cabrini G, Illsley NP, Verkman AS. External anions regulate stilbene -sensitive proton conductance in placental brush border vesicles. Biochemistry 25, 6300-6305, 1986

Cabrini G, Verkman AS. Localization of cyanine dye binding to brush border membranes by quenching of n-(9-anthroyloxy) fatty acid probes. Biochim Biophys Acta 862, 285-293, 1986

Cabrini G, Verkman AS. Potential sensitive response mechanism of DiS-C3(5) in biological membranes. J Membrane Biol 92, 171-182, 1986

Cabrini G, Verkman AS. Mechanism of interaction of the cyanine dye DiS-C3(5) with renal brush border vesicles. J Membrane Biol 90, 163-175, 1986

Berton G, Cassatella M, Cabrini G, Rossi F. Activation of mouse macrophages causes no changes in expression and function of phorbol diesters receptors but is accompanied by alterations in the activity and kinetic parameters of NADPH oxidase. Immunology 54, 371-379, 1985

Rossi F, Della Bianca V, Greskowiak M, De Togni P, Cabrini G. Relationship between phosphoinositide metabolism Ca2+ changes and respiratory burst in formyl-leucyl-phenilalanine stimulated human neutrophils. The breakdown of phosphoinositide is not involved in the rise of cytosolic free Ca2+. FEBS Lett 181, 253-258, 1985

De Togni P, Cabrini G, Di Virgilio F. Cyclic AMP inhibition of fMet-Leu-Phe-dependent metabolic responses in human neutrophils is not due to its effect on cytosolic calcium. Biochem J 224, 629-635, 1984

update 2020 12 06

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