Pubblicazioni

1.     Src activation triggers capacitation and acrosome reaction but not motility in human spermatozoa. Varano G, Lombardi A, Cantini G, Forti G, Baldi E, and Luconi M; Hum Reprod. 2008 Dec; 23(12): 2652-62.

2.     A new mechanism involving ERK contributes to rosiglitazone inhibition of tumor necrosis factor-alpha and interferon gamma inflammatory effects inhuman endothelial cells. Lombardi A, Cantini G, Piscitelli E, Gelmini S, Francalanci M, Mello T, Ceni E, Varano G, Forti G, Rotondi M, Galli A, Serio M, and Luconi M; Arterioscler Thromb Vasc Biol. 2008 Apr; 28(4): 718-24

3.     Thymic development beyond b-selection requires phosphatidylinositol 3-kinase activation by CXCR4. Janas ML, Varano G, Gudmundsson K, Noda M, Nagasawa T, and Turner M; J Exp Med. 2010 Jan; 207(1): 247-61

4.     EZH2 contributes to lymphomagenesis via regulation of the germinal center response. Caganova M, Carrisi C°, Varano G°, Federica M, Federica Z, Germain PL, George L, Alberghini F, Ferrarini L, Talukder AK, Ponzoni M, Testa G, NojimaT, Doglioni C, Kitamura D, Toellner KM, Su I and Casola S; J Clin Invest. 2014 Apr; 124(4): 1869 (° Equal contribution)

5.     miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth. Mihailovich M, Bremang M, Spadotto V, Musiani D, Vitale E, Varano G, Zambelli F, Mancuso FM, Cairns DA, Pavesi G, Casola S, Bonaldi T. Nat Commun. 2015 Nov 10;6:8725.

6.     The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition. Varano G°, Raffel S°, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee           AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, Siebert R, Kempa S, Ponzoni M,        Facchetti F, Rajewsky K, Casola S. Nature. 2017 Jun 8;546(7657):302-306. (° Equal contribution)

7.     Mzoughi S, Fong JY, Papadopoli D, Koh CM, Hulea L, Pigini P, Di Tullio F, Andreacchio G, Hoppe MM, Wollmann H, Low D, Caldez MJ, Peng Y, Torre D, Zhao JN, Uchenunu O, Varano G, et al. PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis. Nat Commun. 2020;11(1):3520. 2020 Jul 14. doi:10.1038/s41467-020-17064-0

8.     Conti I, Varano G, Simioni C, Laface I, Milani D, Rimondi E, Neri LM. miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment. Cells. 2020;9(1)

9.      Costanzi E, Simioni C, Conti I, Laface I, Varano G, Brenna C, Neri LM. Two neuroendocrine G protein-coupled receptor molecules, somatostatin and melatonin: Physiology of signal transduction and therapeutic perspectives. J Cell Physiol. 2020 Sep 28. doi: 10.1002/jcp.30062

10.  Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 2021. D J Klionsky et al. 2021 Feb 8;1-382. doi: 10.1080/15548627.2020.1797280

11.    Cumpelik A, Heja D, Hu Y, Varano G, Roberto M, Homann D, Lira S, Dominguez-Sola D and Heeger PS. Dynamic regulation of B-cell Complement Signaling is Integral to Germinal Center Responses Nat Imm. 2021 In press

12.    Varano G°, Roberto M°, Homes AB, et al. - FOXO1 mutations mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis. - Immunity 2021, under consideration. ° Equal contribution