Valeria Bertagnolo was born in Salara (Rovigo) on 22/08/1961.
1986: Degree in Biological Sciences, University of Ferrara, Italy;
1990: PhD on Cellular and Molecular Biology, University of Ferrara, Italy;
1990: Post-doc EMBO fellowship, University of Utrecht, Netherlands;
1990: Visiting scientist, Center for Biomembranes and Lipid Enzymology, Utrecht, Netherlands;
1990-2004: Researcher, Department of Morphology and Embryology, University of Ferrara, Italy;
2001-present: Member of the PhD Programme (Dottorato di Ricerca) on "Biomedical Sciences";
2005-present: Associate Professor of Human Anatomy, School of Medicine, University of Ferrara, Italy.
- Chief of the Signal Transduction Unit, Laboratory of Cell Biology, Department of Morphology and Embryology, University of Ferrara, since 1987, her main research interest has been focused on the lipid dependent-signal transduction pathways during cell growth and differentiation. Her studies led to the identification and the possible role, in both whole cell and nuclear compartment, of specific isoforms of PKC, PI-PLC, PI3K and Vav1 during the overcoming of the differentiation blockade of APL-derived tumoral promyelocytes (leukemic blasts, cell lines as HL-60 and NB4) induced by agonists (trans-retinoic acid, As2O3). A more recent research interest concerns the role of specific PLC isoforms, both cytoplasmic and nuclear, in promotion and/or progression of breast cancer. Her activity allowed to the identification of molecular targets for antineoplastic strategies.
- Internationally recognized expertise related to cell systems and technological approaches. The main skills acquired were related to all aspects of proteins study (functional proteomics), as immunochemical, immunocytochemical and immunohistochemical analysis, positive and negative modulation of protein expression, specific enzymatic activity assays, comparative analysis of protein expression by classical two-dimensional electrophoresis and DIGE coupled to mass spectrometry.
- Author of an original contribution to the Atlas of Genetics and Cytogenetics in Oncology and Hematology as reference expert for Phospholipase C beta2.
- She has attended several national and international scientific meetings on signal transduction and she is author or co-author of 50 full-length peer-reviewed papers published in international scientific journals (ISI Citation Index: 1311).
- Member of the Italian Society of Anatomy and Histology.
- Associated Editor of Journal of Integrated OMICS.
- Ad hoc reviewer for: Leukemia, Experimental Cell Research, FASEB J, J Integrated OMICS.
- She has been supported by grants from Italian Ministry for University and Scientific Research, Italian Ministry for Foreign Affairs, Italian Ministry of Health and local funds from University of Ferrara.
1986: Degree in Biological Sciences, University of Ferrara, Italy;
1990: PhD on Cellular and Molecular Biology, University of Ferrara, Italy;
1990: Post-doc EMBO fellowship, University of Utrecht, Netherlands;
1990: Visiting scientist, Center for Biomembranes and Lipid Enzymology, Utrecht, Netherlands;
1990-2004: Researcher, Department of Morphology and Embryology, University of Ferrara, Italy;
2001-present: Member of the PhD Programme (Dottorato di Ricerca) on "Biomedical Sciences";
2005-present: Associate Professor of Human Anatomy, School of Medicine, University of Ferrara, Italy.
- Chief of the Signal Transduction Unit, Laboratory of Cell Biology, Department of Morphology and Embryology, University of Ferrara, since 1987, her main research interest has been focused on the lipid dependent-signal transduction pathways during cell growth and differentiation. Her studies led to the identification and the possible role, in both whole cell and nuclear compartment, of specific isoforms of PKC, PI-PLC, PI3K and Vav1 during the overcoming of the differentiation blockade of APL-derived tumoral promyelocytes (leukemic blasts, cell lines as HL-60 and NB4) induced by agonists (trans-retinoic acid, As2O3). A more recent research interest concerns the role of specific PLC isoforms, both cytoplasmic and nuclear, in promotion and/or progression of breast cancer. Her activity allowed to the identification of molecular targets for antineoplastic strategies.
- Internationally recognized expertise related to cell systems and technological approaches. The main skills acquired were related to all aspects of proteins study (functional proteomics), as immunochemical, immunocytochemical and immunohistochemical analysis, positive and negative modulation of protein expression, specific enzymatic activity assays, comparative analysis of protein expression by classical two-dimensional electrophoresis and DIGE coupled to mass spectrometry.
- Author of an original contribution to the Atlas of Genetics and Cytogenetics in Oncology and Hematology as reference expert for Phospholipase C beta2.
- She has attended several national and international scientific meetings on signal transduction and she is author or co-author of 50 full-length peer-reviewed papers published in international scientific journals (ISI Citation Index: 1311).
- Member of the Italian Society of Anatomy and Histology.
- Associated Editor of Journal of Integrated OMICS.
- Ad hoc reviewer for: Leukemia, Experimental Cell Research, FASEB J, J Integrated OMICS.
- She has been supported by grants from Italian Ministry for University and Scientific Research, Italian Ministry for Foreign Affairs, Italian Ministry of Health and local funds from University of Ferrara.
