Silvano Capitani (M.D.)
Born in Gaggio Montano (Bologna ) on 12/06/1948.
EDUCATION
1971 Degree in Biological Sciences (magna cum laude) University of Bologna.
1980 MD degree (magna cum laude), University of Chieti, School of Medicine.
ACADEMIC POSITIONS
1972-1974 University of Bologna, Medical Faculty, Institute of Histology /Post-Doctoral Fellow
1974-1980 University of Chieti, Faculty of Medical Sciences/Assistant Professor
1981-present University of Ferrara, Medical Faculty / Professor of Human Anatomy
INSITUTIONAL APPOINTEMENTS
1999-2001 President of the Quality Assessment Committee (Nucleo di Valutazione) of the University of Ferrara
2007-2011 Director of the Department of Morphology and Embryology, University of Ferrara
RESEARCH ACTIVITY
Head of the Signal Transduction Unit, Laboratory of Cell Biology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
Research Appointments and Stages in International Research Institutes
1977 Italo American Medical Education Foundation /Research Fellowship
1977 Council for International Exchange of Scholars/Fulbright Travel Fellowship
1977-1978 USUHS, Bethesda, Department of Biochemistry/Teaching-Research Associate
1985 SUNYAB, Dept. of Biological Sciences/NATO Visiting Professor
1986 Department of Pharmacology/Emory University School of Medicine, Atlanta, Visiting Fellow
1986 Dept. of Biochemistry/Uniformed Services University of the Health Sciences, Bethesda, Visiting Professor
1987 Laboratory of Biochemistry/State University of Utrecht, Visiting Professor
1987 Glaxo Institute for Molecular Biology (GIMB)/Genève, Visiting Professor
1988-1989 Center for Biomembranes and Lipid Enzymology/State University of Utrecht, Guest Researcher
Association to scientific institutions
1990-2003 Istituto di Citomorfologia del CNR, Chieti /Member of the Scientific Advisory Board
2001-2003 Rovigo International Cancer Center/Member of the Scientific Advisory Board
Participation in/ Coordination of Research Projects
1989-1991 CNR Joint Research Program/GIMB, Genève
1992-1994 CNR Joint Research Project/Center for Lipid Enzymology/ University of Utrecht
1993 – 1996 British Council - Joint Project/AFRC, Cambridge
1984-1990/ MURST - National Project "Cell structure and Function" /Central Coordinator
1993-1998/ CNR-Project Oncology (ACRO)/ Principal Investigator and Director of a research unit
2001-2004/ Ministry of Health (ISS)/ Principal Investigator and Director of research units on special programmes
1999-2000 MIUR National Coordinator of a PRIN project on signal transduction
For the years 2003-2004, 2005-2006, 2007-2008, 2009-2010 MIUR Coordinator-Site Unit of PRIN projects on signal transduction
2010-present MIUR Coordinator-Site Unit of a FIRB project on preclinical and translational research
Additional research project funded by AIRC, Fidia and Fidia Advanced Biopolymers and from the University of Ferrara
Other research skills
Since 1984, Coordinator of Committees for Research Fund allocation of the University of Ferrara
1998-1999, President of the Committee for allocation of funds of a University of Ferrara/Arcispedale S. Anna Joint Research Program
2000-present: Coordinator of a Ph.D. Programme (Dottorato di Ricerca) “Biomedical Sciences “, University of Ferrara, Italy
1999-present Life Sciences Expert Evaluator/ European Commission, EU FP5,6,7 and Horizon 2020
Ad hoc reviewer for: Biochim Biophys Acta, Biochem Biophys Res Co, J Neurochem, Brain Res, Exptl Cell Res, Digestive Diseases and Sciences, J. Cell Sci., Tumori, J.Immunol., Eur. J. Cell Biol., Acta Pharm. Sinica, Stem Cells, Cancer Letters, FASEB J., Br. J. Pharmacol., Leukemia.
Consultant of The Wellcome Trust (reviewer of grant applications)
Author of original contributions to the Atlas of Genetics and Cytogenetics in Oncology and Hematology as reference expert for Phospholipase C beta2, Tumor Necrosis Factor Ligand (TNFSF10), Osteoprotegerin (TNFRSF11B) and AKT1.
Major research expertise
Lipid-dependent signal transduction; lipid-derived second messengers; protein kinase C; lipid transfer proteins; signaling mediated by PLCs and PI3-K; control of proliferation, differentiation and apoptosis; molecular basis of the effects of viral proteins, differentiating agents and growth factors on lymphoid and neuronal cells.
Current research interests include the study of the molecular basis of neoplastic transformation in several models, such as solid tumors and haematological malignancies. A major goal of the research activity is devoted to the identification of markers of malignant evolution of breast cancer, combining several approaches of molecular and cellular biology in order to identify molecular targets for antineoplastic strategies.
Current major international collaborations include Prof. Carlo Croce, Ohio State University in the field of breast cancer, and Mario Tschan, University of Bern, for studies on autophagy.
The relevance and the impact of the scientific activity is certified by the following bibliometric
indexes:
-Author of 198 peer-reviewed scientific publications, present in PubMed.
For the complete list of publications, see the link http://www.ncbi.nlm.nih.gov/pubmed/?term=capitani+s
-Total impact factor >800 (Journal Citation Reports, Science Edition 2014);
-Citations (Web of Knowledge of ISI) >6500
-Hirsch index/H-index=48
Born in Gaggio Montano (Bologna ) on 12/06/1948.
EDUCATION
1971 Degree in Biological Sciences (magna cum laude) University of Bologna.
1980 MD degree (magna cum laude), University of Chieti, School of Medicine.
ACADEMIC POSITIONS
1972-1974 University of Bologna, Medical Faculty, Institute of Histology /Post-Doctoral Fellow
1974-1980 University of Chieti, Faculty of Medical Sciences/Assistant Professor
1981-present University of Ferrara, Medical Faculty / Professor of Human Anatomy
INSITUTIONAL APPOINTEMENTS
1999-2001 President of the Quality Assessment Committee (Nucleo di Valutazione) of the University of Ferrara
2007-2011 Director of the Department of Morphology and Embryology, University of Ferrara
RESEARCH ACTIVITY
Head of the Signal Transduction Unit, Laboratory of Cell Biology, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara
Research Appointments and Stages in International Research Institutes
1977 Italo American Medical Education Foundation /Research Fellowship
1977 Council for International Exchange of Scholars/Fulbright Travel Fellowship
1977-1978 USUHS, Bethesda, Department of Biochemistry/Teaching-Research Associate
1985 SUNYAB, Dept. of Biological Sciences/NATO Visiting Professor
1986 Department of Pharmacology/Emory University School of Medicine, Atlanta, Visiting Fellow
1986 Dept. of Biochemistry/Uniformed Services University of the Health Sciences, Bethesda, Visiting Professor
1987 Laboratory of Biochemistry/State University of Utrecht, Visiting Professor
1987 Glaxo Institute for Molecular Biology (GIMB)/Genève, Visiting Professor
1988-1989 Center for Biomembranes and Lipid Enzymology/State University of Utrecht, Guest Researcher
Association to scientific institutions
1990-2003 Istituto di Citomorfologia del CNR, Chieti /Member of the Scientific Advisory Board
2001-2003 Rovigo International Cancer Center/Member of the Scientific Advisory Board
Participation in/ Coordination of Research Projects
1989-1991 CNR Joint Research Program/GIMB, Genève
1992-1994 CNR Joint Research Project/Center for Lipid Enzymology/ University of Utrecht
1993 – 1996 British Council - Joint Project/AFRC, Cambridge
1984-1990/ MURST - National Project "Cell structure and Function" /Central Coordinator
1993-1998/ CNR-Project Oncology (ACRO)/ Principal Investigator and Director of a research unit
2001-2004/ Ministry of Health (ISS)/ Principal Investigator and Director of research units on special programmes
1999-2000 MIUR National Coordinator of a PRIN project on signal transduction
For the years 2003-2004, 2005-2006, 2007-2008, 2009-2010 MIUR Coordinator-Site Unit of PRIN projects on signal transduction
2010-present MIUR Coordinator-Site Unit of a FIRB project on preclinical and translational research
Additional research project funded by AIRC, Fidia and Fidia Advanced Biopolymers and from the University of Ferrara
Other research skills
Since 1984, Coordinator of Committees for Research Fund allocation of the University of Ferrara
1998-1999, President of the Committee for allocation of funds of a University of Ferrara/Arcispedale S. Anna Joint Research Program
2000-present: Coordinator of a Ph.D. Programme (Dottorato di Ricerca) “Biomedical Sciences “, University of Ferrara, Italy
1999-present Life Sciences Expert Evaluator/ European Commission, EU FP5,6,7 and Horizon 2020
Ad hoc reviewer for: Biochim Biophys Acta, Biochem Biophys Res Co, J Neurochem, Brain Res, Exptl Cell Res, Digestive Diseases and Sciences, J. Cell Sci., Tumori, J.Immunol., Eur. J. Cell Biol., Acta Pharm. Sinica, Stem Cells, Cancer Letters, FASEB J., Br. J. Pharmacol., Leukemia.
Consultant of The Wellcome Trust (reviewer of grant applications)
Author of original contributions to the Atlas of Genetics and Cytogenetics in Oncology and Hematology as reference expert for Phospholipase C beta2, Tumor Necrosis Factor Ligand (TNFSF10), Osteoprotegerin (TNFRSF11B) and AKT1.
Major research expertise
Lipid-dependent signal transduction; lipid-derived second messengers; protein kinase C; lipid transfer proteins; signaling mediated by PLCs and PI3-K; control of proliferation, differentiation and apoptosis; molecular basis of the effects of viral proteins, differentiating agents and growth factors on lymphoid and neuronal cells.
Current research interests include the study of the molecular basis of neoplastic transformation in several models, such as solid tumors and haematological malignancies. A major goal of the research activity is devoted to the identification of markers of malignant evolution of breast cancer, combining several approaches of molecular and cellular biology in order to identify molecular targets for antineoplastic strategies.
Current major international collaborations include Prof. Carlo Croce, Ohio State University in the field of breast cancer, and Mario Tschan, University of Bern, for studies on autophagy.
The relevance and the impact of the scientific activity is certified by the following bibliometric
indexes:
-Author of 198 peer-reviewed scientific publications, present in PubMed.
For the complete list of publications, see the link http://www.ncbi.nlm.nih.gov/pubmed/?term=capitani+s
-Total impact factor >800 (Journal Citation Reports, Science Edition 2014);
-Citations (Web of Knowledge of ISI) >6500
-Hirsch index/H-index=48
