Paola Secchiero: Date and Place of Birth: November 6, 1966; Rovigo, Italy.
EDUCATION:
1989: Doctor of Sciences, Laurea with Honors, Biological Sciences, University of Ferrara; 1990-1994: Ph.D. (Biochemistry and Molecular Biology), Institute of Microbiology, University of Ferrara, Italy.
POSITIONS IN INTERNATIONAL INSTITUTIONS:
- From June 1992 to June 1994: Guest Researcher supported by an AIDS research fellowship of the Italian Ministry of Health, at the Laboratory of Tumor Cell Biology, headed by Dr. Robert C. Gallo, National Cancer Institute [NCI], National Institutes of Health [NIH], Bethesda, Maryland-USA;
- From June 1994 to March 1996: Visiting Fellow supported by a Fogarty Fellowship at the Laboratory of Tumor Cell Biology, headed by Dr. Robert C. Gallo, National Cancer Institute [NCI], National Institutes of Health [NIH], Bethesda, Maryland-USA;
- From April 1996 to January 2000: Research Associate at the Laboratory of Cell Biology, Division of Basic Science, Institute of Human Virology, Medical Biotechnology Center, headed from Dr. Robert C.
Gallo (University of Maryland, Baltimore, Maryland-USA);
- From January to September 2000: Assistant Professor at the Laboratory of Cell Biology, Division of
Basic Science, dell'Institute of Human Virology, Medical Biotechnology Center, headed from Dr. Robert C. Gallo (University of Maryland, Baltimore, Maryland-USA).
ACADEMIC APPOINTMENTS:
- From 1 September 2000 to 31 October 2001: Researcher/Assistant Professor of Human Anatomy, at the Faculty of Pharmacy of the University of Ferrara;
- From 1 November 2001 to 31 October 2006: Associate Professor of Human Anatomy, at the Faculty of Pharmacy of the University of Ferrara;
- From 1 November 2006- present: Full Professor od Human Anatomy, at the Faculty of Medicine and Surgery, University of Ferrara;
- From August 2001-present: Adjunct Professor, Division of Basic Science of the Institute of Human Virology, Medical Biotechnology Center, Prof. Robert C. Gallo (University of Maryland, Baltimore, Maryland-USA).
ADDITIONAL APPOINTMENTS:
- Professor of the PhD program in Pharmacology and Molecular Oncology, University of Ferrara;
- March 2000-present: Scientific Head of the Intedepartmental Center "Laboratory of Technologies for Advanced Therapies" (LTTA) of University of Ferrara.
SCIENTIFIC ACTIVITY:
The main reseach interest of Prof. Paola Secchiero at the Department of Morphology and Embryology, University of Ferrara, Italy since 2000, mainly regards the study of molecular mechanisms modulating apoptosis in oncohematology, and the role of the TRAIL/TRAIL-R system in normal and neoplastic hematopoiesis as well as in the cardiovascular physiopathology.
Prof. Secchiero is author of 150 peer-reviewed scientific publications, present in PubMed, with a total impact factor >860 (Journal Citation Reports, Science Edition 2010).
To date, the scientific publications of Prof. Paola Secchiero have received >3000 citations, H index=34 (Web of Knowledge of ISI).
FINANCED PROJECTS:
Principal Investigator of the following grants:
- Italian National Research Coucil (CNR – Young Project) 2001: “Signal transduction pathways induced by TNF-related apoptosis-inducing ligand (TRAIL) in hematopoietic cells”;
- Local grants of the University of Ferrara from 2002 to now: “Study of the mechanisms of action of recombinant TRAIL in hematological malignancies: cellular and molecular bases for therapeutic strategies”;
- Ministery of Health-AIDS project 2002: “Opportunistic infections induced by human herpesviruses in AIDS patients: role in the induction of immunological abnormalities and cytopenias”;
- Ministery of Health-Stem Cell project 2003-2004: “Development of chimeric viral vectors for the correction of genetic diseases affecting hematopoietic stem/progenitor cells”;
- MIUR/FIRB project 2002-2005: “Study of the anti-tumoral activity of TRAIL in combination with chemotherapeutic drugs”;
- MIUR/PRIN project 2004-2005: “Role of TRAIL/Apo-2L in the physiopathology of endothelial and hemopoietic systems”;
- MIUR/PRIN project 2006-2008: “Role of TRAIL/Apo-2L in the physiopathology of endothelial and
hemopoietic systems”;
- Regional Emilia Romagna-Health project: “Establishment of a regional network to investigate, by applying a translational approach, the role of stem cell therapy in Coronary Artery Disease (CAD) patients with advanced left ventricular (LV) dysfunction”;
- CariFe Foundation project 2007-2009: “Production of biotechnological drugs with anti-tumoral activity
against leukemic stem cells”.
- MIUR/FIRB project 2010-2014: "Cancer stem cells: cellular signalling pathways as potential tagets for therapy".
EDUCATION:
1989: Doctor of Sciences, Laurea with Honors, Biological Sciences, University of Ferrara; 1990-1994: Ph.D. (Biochemistry and Molecular Biology), Institute of Microbiology, University of Ferrara, Italy.
POSITIONS IN INTERNATIONAL INSTITUTIONS:
- From June 1992 to June 1994: Guest Researcher supported by an AIDS research fellowship of the Italian Ministry of Health, at the Laboratory of Tumor Cell Biology, headed by Dr. Robert C. Gallo, National Cancer Institute [NCI], National Institutes of Health [NIH], Bethesda, Maryland-USA;
- From June 1994 to March 1996: Visiting Fellow supported by a Fogarty Fellowship at the Laboratory of Tumor Cell Biology, headed by Dr. Robert C. Gallo, National Cancer Institute [NCI], National Institutes of Health [NIH], Bethesda, Maryland-USA;
- From April 1996 to January 2000: Research Associate at the Laboratory of Cell Biology, Division of Basic Science, Institute of Human Virology, Medical Biotechnology Center, headed from Dr. Robert C.
Gallo (University of Maryland, Baltimore, Maryland-USA);
- From January to September 2000: Assistant Professor at the Laboratory of Cell Biology, Division of
Basic Science, dell'Institute of Human Virology, Medical Biotechnology Center, headed from Dr. Robert C. Gallo (University of Maryland, Baltimore, Maryland-USA).
ACADEMIC APPOINTMENTS:
- From 1 September 2000 to 31 October 2001: Researcher/Assistant Professor of Human Anatomy, at the Faculty of Pharmacy of the University of Ferrara;
- From 1 November 2001 to 31 October 2006: Associate Professor of Human Anatomy, at the Faculty of Pharmacy of the University of Ferrara;
- From 1 November 2006- present: Full Professor od Human Anatomy, at the Faculty of Medicine and Surgery, University of Ferrara;
- From August 2001-present: Adjunct Professor, Division of Basic Science of the Institute of Human Virology, Medical Biotechnology Center, Prof. Robert C. Gallo (University of Maryland, Baltimore, Maryland-USA).
ADDITIONAL APPOINTMENTS:
- Professor of the PhD program in Pharmacology and Molecular Oncology, University of Ferrara;
- March 2000-present: Scientific Head of the Intedepartmental Center "Laboratory of Technologies for Advanced Therapies" (LTTA) of University of Ferrara.
SCIENTIFIC ACTIVITY:
The main reseach interest of Prof. Paola Secchiero at the Department of Morphology and Embryology, University of Ferrara, Italy since 2000, mainly regards the study of molecular mechanisms modulating apoptosis in oncohematology, and the role of the TRAIL/TRAIL-R system in normal and neoplastic hematopoiesis as well as in the cardiovascular physiopathology.
Prof. Secchiero is author of 150 peer-reviewed scientific publications, present in PubMed, with a total impact factor >860 (Journal Citation Reports, Science Edition 2010).
To date, the scientific publications of Prof. Paola Secchiero have received >3000 citations, H index=34 (Web of Knowledge of ISI).
FINANCED PROJECTS:
Principal Investigator of the following grants:
- Italian National Research Coucil (CNR – Young Project) 2001: “Signal transduction pathways induced by TNF-related apoptosis-inducing ligand (TRAIL) in hematopoietic cells”;
- Local grants of the University of Ferrara from 2002 to now: “Study of the mechanisms of action of recombinant TRAIL in hematological malignancies: cellular and molecular bases for therapeutic strategies”;
- Ministery of Health-AIDS project 2002: “Opportunistic infections induced by human herpesviruses in AIDS patients: role in the induction of immunological abnormalities and cytopenias”;
- Ministery of Health-Stem Cell project 2003-2004: “Development of chimeric viral vectors for the correction of genetic diseases affecting hematopoietic stem/progenitor cells”;
- MIUR/FIRB project 2002-2005: “Study of the anti-tumoral activity of TRAIL in combination with chemotherapeutic drugs”;
- MIUR/PRIN project 2004-2005: “Role of TRAIL/Apo-2L in the physiopathology of endothelial and hemopoietic systems”;
- MIUR/PRIN project 2006-2008: “Role of TRAIL/Apo-2L in the physiopathology of endothelial and
hemopoietic systems”;
- Regional Emilia Romagna-Health project: “Establishment of a regional network to investigate, by applying a translational approach, the role of stem cell therapy in Coronary Artery Disease (CAD) patients with advanced left ventricular (LV) dysfunction”;
- CariFe Foundation project 2007-2009: “Production of biotechnological drugs with anti-tumoral activity
against leukemic stem cells”.
- MIUR/FIRB project 2010-2014: "Cancer stem cells: cellular signalling pathways as potential tagets for therapy".
