Prof. Carlo Contini

Born in Porto Torres (SS) on 15-12-1954
Citizenship: Italian
Residence: Ferrara, Via Valle Mantello, 53

Education

2005-present: Full Professor of Infectious and Tropical Diseases at the University of Ferrara
1992-2005: Associate Professor of Infectious and Tropical Diseases at the University of Ferrara
1986-1992: Highly professional graduate technician at the Department of Infectious and Tropical Diseases at "La Sapienza" University of Rome
1983-1986: Specialization in Allergology and Clinical Immunology at "la Sapienza" University of Rome (70 cum laude).
1980-1983: Specialization in Infectious and Tropical Diseases at L'Università "la Sapienza" in Rome (70 cum laude)
1980: Degree cum laude in Medicine and Surgery at the University of Sassari
1979: Voluntary attendance at the "Service de Virologie" and "Maladies Infectieuses et Tropicales," Institut Pasteur, Paris
1974: Classical high school diploma, Liceo Azuni, Sassari

Teaching Activities

2023- 2024: Lecturer in the Postgraduate Course in Science Communication and Public Engagement
1993-Present: Teaching of Infectious Diseases in the Graduate Courses in Medicine (47811), Dentistry and Dental Prosthetics (000671) in the University of Ferrara
2017-2023: Coordinator School of Specialization of Infectious and Tropical Diseases in Ferrara aggregated with Parma, Modena and Reggio Emilia.
2013-2022: Lecturer within the Doctoral Program in Molecular Medicine and Pharmacology at the Ateneo Estense University
2012-2017: Coordinator School of Specialization in Infectious and Tropical Diseases aggregated with Bologna, Parma, Modena and Reggio Emilia.
2006-2010: Teaching of Traditional and Emerging Tropical Infectious Diseases (43386) in the University of Ferrara.
2005-2010: Teaching of Infectious Diseases in Dental Hygiene in the University of Ferrara.
2005-2011: Director Postgraduate School of Infectious Diseases in the University of Ferrara.
2005-2018: Lecturer in Infectious Diseases and Co-Director (Director Prof. R. Stockbrugger) in the Elective Course of Medicine Graduation - Abdominal Compliance Outside Europe and North America-, F.A.M.E. COURSE 2.3 (Maastricht)
1995-1997: Teaching of Clinical Microbiology in the University of Ferrara
2003-Present: Teaching of Infectious Diseases in the following Specialization Schools of the University of Ferrara: Hygiene and Preventive Medicine, Rheumatology, Clinical Pathology, Dermatology, Internal Medicine, Gastroenterology, Medical Oncology, Clinical Pathology and Clinical Biochemistry Mixed-access health care area

Scientific Activity.

Impact Factor: >400 (ISI-WoS ranking), H-INDEX Scopus = 24, citations: > 2,300; H-INDEX Google Scholar = 30, i10-index 94, citations 3,554.
He has authored and co-authored numerous publications in national and international journals on topics in Infectious Diseases, Immunology and Clinical Microbiology of which:
- over 125 in international peer reviewed journals with IF indexed on PubMed, Scopus, Web of Science
- articles in journals with ISBN and ISSN, conference proceedings in National and International Conferences
- over 400 abstracts
- 21 book chapters of which 6 are international
- 1 book

Research Interests.

SARS-CoV-2 and COVID-19 (2020-present), viral hepatitis (2012-2022), infections in the History of Medicine (2010-present), tuberculosis (2010-2022), leishmaniasis (2018-2024), Mycoplasma and Chlamydia infections (2003-present), Central Nervous System infections (2003-2020), HIV/AIDS and AIDS-related opportunistic infections - Pneumocystis Jiroveci, Toxoplasma gondii, Cytomegalovirus (1989-2018), experimental infections (Sprague Dowley and Wistar rats with pharmacologically induced PCP and development of in vitro culture systems for P. carinii and T. gondii on A549, CEL, HEL, VERO, WI 38, VA 13 cell lines), liquid chromatography (HPLC) and advanced immunodiagnostic tests at the Department of Infectious Diseases, University "La Sapienza" Rome (1988-1993) and Laboratoire de Parasitologie, Universitè "Claude Bernard", Lyon, France(1989-2003); fabrication and characterization of monoclonal anti-P. carini antibodies for biological diagnosis of PCP (fusion of myeloma cells (X63-AG8.653) with splenocytes obtained from Biozzi mice - Department de Biotechnologie, Institut Pasteur, Paris (1991-1992), hydatidosis and other parasitic diseases (1981-1986).

Research stays abroad

2010: "Department of Biological Sciences" (Prof. E. Kaneshiro), University of Cincinnati, Ohio, USA
2006-2008: "Service des Mycoplasmes et Chlamydiae," Unitè de Biologie Cellulaire (Prof. A. Dautry-Varsat, Institut Pasteur, Paris)
2000: Intern at Hopital de Maladies Infectieuses, (Prof. P. Lapresle), Touluse, France
1999-2000: Visiting Scientist at "Groupe Immunité des Muqueuses et Agents Pathogenes" (GIMAP (Prof. A. Genin), Université "Jacques Lisfrang", Saint-Etienne, France) and Universitè Claude Bernard, Lyon, France; "Rapporteur" of experimental theses at the same universities
1989-2003: "Department de Pathologie Exotique et Maladies Tropicales" (Prof. M. Mojon, F. Peyron, Université "Claude Bernard," Lyon, France)
1987-1996: Visiting Scientist at the "Department de Biotechnologie" (Dr. F. Nato, Institut Pasteur, Paris)
1979: Voluntary attendance at the Centre National de Référence de la Rage - (Prof. P. Atanasiu), Institut Pasteur, Paris

Organizer of national, international conferences and seminars including:

International Conference "Neglected Tropical Diseases Congress: The Future Challenges" (October 2018, Abu Dhabi - Member of the Organizing Committee)
National Conference "The Infectious Diseases of the Migrant and Traveler," Ferrara - Biennial editions held in 2008, 2010, 2012, 2014, 2016.
National Conference: "Hot Topics in Infectious Diseases" (Ferrara, Sept. 23, 2015)
18th Congress of the International Organization of Mycoplasmology (IOM) (Chianciano, Italy, May 11, 2010)
National Conference: "Osteomyelitis and Prosthetic Infections," Ferrara December 4, 2009
International Symposium on "Toxoplasmosis," XXV° Conference of the Italian Society of Parasitology - SOIPA (Pisa, June 18-21, 2008)
International Conference on "Chlamydia and Mycoplasma Human Infections" (Ferrara, April 19-20, 2007)
National Conference: "Chlamydia Infections: Current Events and Perspectives" (Ferrara, December 2, 2006)
3rd National Theoretical-Practical Course on "Imported Infectious and Parasitic Diseases. Diagnostic and Therapeutic Actualities" (Ferrara, June 6-8, 2006)
2nd National Theoretical-Practical Course on "Imported Infectious and Parasitic Diseases. Diagnostic and Therapeutic Actualities, (Ferrara, June 6-8, 2005)
1st National Theoretical-Practical Course of "Diagnostic Parasitology. Emerging Parasitoses," (Ferrara, June 22-24, 2004)
National Conference "Toxoplasmosis," Present and Future (Ferrara June 24, 2000)
Seminars on Topics in Infectious Diseases for the University for Continuing Education-Utef- (2023-2011)
Annual lectures entitled "AIDS: The Global Situation. AIDS Celebration Day (1994-2010), University of Ferrara.

Research Projects and Funding

Responsible for numerous national, regional and local research projects of which some:

1993-present: FAR projects from University of Ferrara
2021-22: New inflammatory and molecular biomarkers in the differential diagnosis of joint replacements with algic symptoms: a pilot study (Comitato Etico di Area Vasta Emilia Centro (CE-AVEC) - Protocol Code: NBIMPJ; EC Internal Code No. 237/2022/Sper/AOUFe)
2020: Determination of antibody response in conjunctival fluid of Covid-19 patients: functional significance and clinical and prognostic perspectives (Comitato Etico di Area Vasta Emilia Centro (CE-AVEC) Protocol Code: EC Internal Code No. EM262-2021_544/2020/Oss/AOUFe).
2017: "Panton-Valentine's Leukocidin in suppurative hydrosadenitis: prevalence and clinical correlation study (CE of Area Vasta Emilia Centro (CE-AVEC) Internal EC Cod No. 171174)
2016: Diagnostic and Clinical Management of Latent Opportunistic Infections in Patients with Chronic Joint Rheumatism Treated with Biologic Drugs (CE of Area Vasta Emilia Centro (CE-AVEC Internal Cod No. 150494)
2013-2016: University-Region Project Coordinator, Topic Area titled Advanced diagnostics: Silent intracellular infections and early pregnancy loss".2008-2011: Funding for controlled clinical trials (Aventis, Roche, Novartis).2007-2011: Coordinator Infectious Disease Unit 1 (Unit 1) within the Research Project Regione Emilia Romagna-University, Area 1°- Innovative Research (Prof. E. Granieri, University of Ferrara), entitled: Regional Network for implementing a Biological Bank to Identify Markers of Diasease activity to Clinical Variables in Multiple Sclerosis (total fund allocated: 712,600.00 euro).
2005-2006: PRIN coordinator for project entitled: Involvement of Mycoplasma and Ureaplasma urealyticum/U. Parvum in Brain Injuries of the Newborn. (Biomarkers, gene expression and pharmacological modulation in hypoxia-ischemia and infection models in vitro and in vivo. 2005069071) in coll with University of Siena (Prof. G. Buonocore)
2003: FEMS (Federation of European Microbiological Societies) Prize, for research project in collaboration with the Laboratoire de Parasitologie et Pathologie Exotique, Universitè Claude Bernard, Lyon, France (Director: Prof. Francois Peyron) entitled: Use of real-time PCR for quantitative determination of T. gondii stage-specific genes in the advanced diagnosis of reactivated T. gondii infection).
1999-2000: Holder of MIUR Projects (40%) for Opportunistic Infections in AIDS.
1995-2011: Grant holder of the Ferrara and Cento Savings Bank Foundations.
1987-89: AIDS Projects Istituto Superiore di Sanità (Advanced diagnosis of Pneumocystis carinii infection in AIDS patients).
1997-2012: Activated No. 11 research grants (12 months) at the Department of Medical Sciences and Department of Clinical and Experimental Medicine.

Editorial Activities

Section Editor of the Journal of Infection in Developing Countries (ISSN 19722680, 20366590);
Member of the editorial board of "Biology" (ISSN 2079-7737).
Review Editor of Extraintestinal and Intestinal Microbiome, Specialty Section of Frontiers in Cellular and Infection Microbiology (ISSN 22352988).
Review Editor of Multiple Sclerosis and Neuroimmunology, Specialty Section of Frontiers in Immunology (ISSN 16643224) and Frontiers in Neurology (ISSN 16642295).
Associate Editor of Infez Med (official journal of the Italian Society of Infectious and Tropical Diseases - ISSN 1124-9390).
Review Editor for Neuroinfectious Diseases (ISSN 1664-2295) special section of Frontiers in Neurology).
Guest Editor of the special issue "Advances in SARS-CoV-2 Infection" and "Advances in SARS-CoV-2 Infection 2nd Edition" for Microorganisms (ISSN 2076-2607).
Guest Editor of the special issue "Opportunistic Viral Infections" for Viruses (ISSN 1999-4915).

Reviewer activities of International Journals

BMC Infectious Diseases, Clinical Infectious Diseases, International Journal of Infectious Diseases, International Journal for Parasitology, Parasitology, Journal of Medical Virology, Microorganisms, Viruses, Infections, Infections in Medicine, Annals of Hepatology, European Journal of Clinical Microbiology & Infectious Diseases, International STD Research & Reviews, Journal of Infections in Developing Countries, Frontiers in Microbiology, Pathogens, Microorganisms, Microbes & Infection, Journal of Infection and Chemotherapy, Journal of Clinical Medicine, International Journal of Molecular Sciences, Biology, Mediators and Inflammation, PlosOne, etc.

Research Contributions and Patents

2008-2009: Contributed to the preparation of molecular diagnostic kits for Chlamydia trachomatis (REALQUALITY RS-CHLAM T, code RQ-S33: Kit for the identification and quantification of C. trachomatis, AB Analytica Advanced Medicine).
1994: Filed an International Patent for the experimental pharmacological treatment of PCP (Patent: United STATES Patent; Application: US19950525526

Membership of Scientific Societies

Italian Society of Infectious and Tropical Diseases (SIMIT)
European Society of Clinical Microbiology and Infectious Diseases (ESCMID)

Other positions

2020-present: Member of the Ferrara Academy of Sciences for the Class of Medical Sciences.
2020-2021: Chairman of the Departmental Commission for the compilation of the SUA-RD Form for Research and Third Mission Assurance.
2013-2016: Representative of the University Directors of Complex Care Structures (UOC) of the School of Medicine of the University of Ferrara.
2011: President of the University Fund for Scientific Research (FAR) Commission for the year 2011
2009-2015: Member of the Ethics Committee of the University of Ferrara.

Welfare activities

2012-present: Head of the University Complex Operative Unit of Infectious and Tropical Diseases in the Arcispedale Sant'Anna Hospital-University of Ferrara (Cona).
2012-2020: Deputy Director of the Medical Assistance Department (DAI) of the Azienda Ospedaliera-Universitaria dell'Arcispedale Sant'Anna of Ferrara.
2005-2012: He directed the Infectious and Tropical Diseases Programme at the Azienda Ospedaliera-Universitaria dell'Arcispedale Sant'Anna of Ferrara.
1993-2005: He directed the outpatient clinic and DH of Infectious Diseases at the S. Anna Hospital of Ferrara.