Curriculum


 

 

 


 

 

 

Europass

Curriculum Vitae

 

 

 

Personal information

 

First name(s) / Surname(s)

Beatrice Paradiso

Address

Via Mentana 39

I-44100 Ferrara (Italy)

Mobile

+393396671973

 

E-mail(s)

beatrice.paradiso@unife.it; Beatrice.Paradiso@med.lu.se (professional adresses)

Date of birth

23 March 1962

Gender

Female

 

 

Desired employment / Occupational field

Medical doctor; Molecular Pharmacologist and Oncologist; Teacher of Pharmacogenetics and Pharmacogenomics.

 

 

Work experience

 

 

 

Dates

20 March 2003 - 31 January 2009

Occupation or position held

University Researcher in Neuropharmacology; Teacher of Pharmacogenetics and Pharmacogenomics

Main activities and responsibilities

Researcher in the field of Neuroscience:

Neuropharmacological and molecular study of Neurodegenerative Diseases, in particular Epilepsy and Stem Cells.

 

Work experiences:

Visiting researcher, Wallenberg Neuroscience Centre, Lund University, Sweden from April to September 2008.

"leonardo" grantholder at NSgene, Denmark from April to September 2008.

Visiting researcher, Wallenberg Neuroscience Centre, Lund University, Sweden from October to November 2006.

Visiting researcher, Wallenberg Neuroscience Centre, Lund University, Sweden from July to September 2004.

Completed internship in the Department of Clinical and Experimental Medicine, Section of Pharmacology at the University of Ferrara from March 2003 to March 2007.

 

Teaching experiences:

Teacher of the Pharmacogenetics and Pharmacogenomics Course, Biotechnology degree, University of Ferrara, Ferrara Italy from September 2007 to present.

Teaching Assistant of Pharmacogenetics and Pharmacogenomics School of Medicine and Biotechnology, School of Specialization in Medical Genetics, University of Ferrara, Ferrara, Italy from 2004 to present.

Second Tutor of degree theses. School of Pharmacy, Biology and Biotechnology, University of Ferrara, Ferrara from 2004 up to Jannuary 2009.

 

Scientific activity:

Author of 5 papers in peer-reviewed journals (see Publications).

Past year project : Effects of defective herpes simplex vectors expressing neurotrophic factors on neural stem cells in vitro and on neurogenesis in vivo, in animal models of epilepsy.

Development of strategies for the localized delivery (by endothelial stem cells or encapsulated cells) of BDNF, together with other NTFs and neuropeptides, in lesion areas, to prompt effective proliferation, differentiation and migration of endogenous neural stem cells for obtaining repair of damage and recovery from neurological deficit.

Implementation of long-term organotypic cultures from human brain tissue

Name and address of employer

Research Group Professor Michele Simonato,MD Professor of Pharmacology and ToxicologyUniversity of Ferrara, Department of Clinical and Experimental Medicine Section of Pharmacology University of Ferrara via Fossato di Mortara 17-1944100 Ferrara Italy ph. +39-0532-455211 fax +39-0532-455205 (up to Jannuary 2009)

Type of business or sector

Research into Neuroscience and Stem Cells (up to Jannuary 2009)

 

 

Education and training

 

 

 

Dates

July 1981 - September 2008

Title of qualification awarded

MD, PhD in Molecular Pharmacology and Oncology, Europass Mobility

Principal subjects / occupational skills covered

Europass Mobility in September 2008

Research PhD in Molecular Pharmacology and Oncology: specializing in Molecular Pharmacology of the Central and Peripheral Nervous System in March 2007, Department of Clinical and Experimental Medicine, Section of Pharmacology, University of Ferrara, Ferrara, Italy. Tutor Prof. Michele Simonato and Dr Silvia Zucchini

Final mark: excellent

State qualifying examination in the use of medicine, in 2003

Final mark: 102/110

Degree in Medicin and Surgery in March 2003, University of Ferrara, Ferrara, Italy

Final mark: 110/110, First Class Honours Degree

"Liceo" specializing in scientific studies (school leaving examination) in July 1981, Liceo Scientifico Statale " Tullio Levi Civita", Codigoro, Ferrara

Final mark: 60/60

Level in national or international classification

ISCED 6

 

 

Personal skills and competences

 

 

 

Mother tongue(s)

Italian

 

 

Other language(s)

 

Self-assessment

 

Understanding

Speaking

W r i t i n g

European level (*)

 

Listening

Reading

Spoken interaction

Spoken production

 

English

 

B2

Independent user

B2

Independent user

B2

Independent user

B2

Independent user

B2

Independent user

 

(*) Common European Framework of Reference (CEF) level

 

 

Social skills and competences

Able to adapt to multicultural situations, thanks to experience working abroad.

 

 

Organisational skills and competences

Experience of managing projects or groups gained during both research and teaching.

 

 

Technical skills and competences

Up to the end of Jannuary 2009 Neuroscience Researcher: Epileptic models (pilocarpine, kainate, kindling); EEG recording; stereotaxis rodents surgery and in vivo infusion by mininvasive surgical procedures; intracerebro implantation of encapsulated cells for biodelivery; intravenous, intacardial and intracerebro micro-infusion of chemical substance and stem cells in rodent; intracardial perfusion of rodents; different cut techniques of histological sections (microtome, freezing microtome, cryostat for fresh, perfused and paraffin-embedded tissue; resin-embedded encapsulated cells), isolation and culture of neural stem cells, isolation and culture of primary ganglionic cells, culture of endothelial stem cells, hippocampal organotypic cultures of pups and adult mice, immunostaining, use of optic and fluorescent microscope, dissection microscope, vibrotome and immunofluorscence staining on vibrotome sections . Cellular stereological analysis. ELISA and PCR

 

 

Computer skills and competences

Microsoft 2000/XP

- Microsoft Office

- PhotoShop [TM]

- Visiopharm Integrator System [TM]

-data processing for morphological and quantitative analysis of biological imaging

 

 

Driving licence(s)

B

 

 

Additional information

Scientific publications:

1. ZUCCHINI S, BUZZI A, BARBIERI M, RODI D, PARADISO B., BINASCHI A, COFFIN J D, MARZOLA A, CIFELLI P, BELLUZZI O, SIMONATO M. (2008). FGF-2 Overexpression Increases Excitability and Seizure Susceptibility but Decreases Seizure-Induced Cell Loss. THE JOURNAL OF NEUROSCIENCE. vol. 28, pp. 13112-13124 ISSN: 0270-6474.

2. FRANCESCHETTI S, SANCINI G, BUZZI A, ZUCCHINI S, PARADISO B.,

MAGNAGHI G, FRASSONI C, CHIKHLADZE M, AVANZINI G, SIMONATO M.

(2007). A pathogenetic hypothesis of Unverricht-Lundborg disease onset and

progression. NEUROBIOLOGY OF DISEASE. vol. 25, pp. 675-685 ISSN: 0969-

9961, ISI:000244872200023.

3. MARCONI P, ZUCCHINI S, BERTO E, BOZAC A, PARADISO B., BREGOLA G,

GRASSI C, VOLPI I, ARGNANI R, MARZOLA A, MANSERVIGI R, SIMONATO M.

(2005). Effects of defective herpes simplex vectors expressing neurotrophic factors

on the proliferation and differentiation of nervous cells in vivo. GENE THERAPY. vol.

12, pp. 559-569 ISSN: 0969-7128, ISI:000227857500004.

4. TONGIORGI E, ARMELLIN M, GIULIANINI PG, BREGOLA G, ZUCCHINI S,

PARADISO B., STEWARD O, CATTANEO A, SIMONATO M. (2004). Brain-derived

neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by

events that trigger epileptogenesis. THE JOURNAL OF NEUROSCIENCE. vol. 24,

pp. 6842-6852 ISSN: 0270-6474, ISI:000222950400027.

5. ZUCCHINI S, RODI D, PARADISO B., BINASCHI A, GRASSIL C, MARZOLA A,

COFFIN JD, SIMONATO M. (2004). Increased susceptibility to kainate seizures and

decreased seizure-induced cell loss in transgenic mice overexpressing fibroblast

growth factor-2. BEHAVIOURAL PHARMACOLOGY. vol. 15, pp. A29 ISSN: 0955-

8810, ISI:000223965700111.

 

 

Annexes

Autorizzo il trattamento dei miei dati personali ai sensi del Decreto Legislativo 30

giugno 2003, n. 196 "Codice in materia di protezione dei dati personali" .

             


 

 

A1

A2

B1

B2

C1

C2

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Listening

I can understand familiar words and very basic phrases concerning myself, my family and immediate concrete surroundings when people speak slowly and clearly.

I can understand phrases and the highest frequency vocabulary related to areas of most immediate personal relevance (e.g. very basic personal and family information, shopping, local area, employment). I can catch the main point in short, clear, simple messages and announcements.

I can understand the main points of clear standard speech on familiar matters regularly encountered in work, school, leisure, etc. I can understand the main point of many radio or TV programmes on current affairs or topics of personal or professional interest when the delivery is relatively slow and clear.

I can understand extended speech and lectures and follow even complex lines of argument provided the topic is reasonably familiar. I can understand most TV news and current affairs programmes. I can understand the majority of films in standard dialect.

I can understand extended speech even when it is not clearly structured and when relationships are only implied and not signalled explicitly. I can understand television programmes and films without too much effort.

I have no difficulty in understanding any kind of spoken language, whether live or broadcast, even when delivered at fast native speed, provided. I have some time to get familiar with the accent.

Reading

I can understand familiar names, words and very simple sentences, for example on notices and posters or in catalogues.

I can read very short, simple texts. I can find specific, predictable information in simple everyday material such as advertisements, prospectuses, menus and timetables and I can understand short simple personal letters.

I can understand texts that consist mainly of high frequency everyday or job-related language. I can understand the description of events, feelings and wishes in personal letters.

I can read articles and reports concerned with contemporary problems in which the writers adopt particular attitudes or viewpoints. I can understand contemporary literary prose.

I can understand long and complex factual and literary texts, appreciating distinctions of style. I can understand specialised articles and longer technical instructions, even when they do not relate to my field.

I can read with ease virtually all forms of the written language, including abstract, structurally or linguistically complex texts such as manuals, specialised articles and literary works.

S

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Spoken interaction

I can interact in a simple way provided the other person is prepared to repeat or rephrase things at a slower rate of speech and help me formulate what I'm trying to say. I can ask and answer simple questions in areas of immediate need or on very familiar topics.

I can communicate in simple and routine tasks requiring a simple and direct exchange of information on familiar topics and activities. I can handle very short social exchanges, even though I can't usually understand enough to keep the conversation going myself.

I can deal with most situations likely to arise whilst travelling in an area where the language is spoken. I can enter unprepared into conversation on topics that are familiar, of personal interest or pertinent to everyday life (e.g. family, hobbies, work, travel and current events).

I can interact with a degree of fluency and spontaneity that makes regular interaction with native speakers quite possible. I can take an active part in discussion in familiar contexts, accounting for and sustaining my views.

I can express myself fluently and spontaneously without much obvious searching for expressions. I can use language flexibly and effectively for social and professional purposes. I can formulate ideas and opinions with precision and relate my contribution skilfully to those of other speakers.

I can take part effortlessly in any conversation or discussion and have a good familiarity with idiomatic expressions and colloquialisms. I can express myself fluently and convey finer shades of meaning precisely. If I do have a problem I can backtrack and restructure around the difficulty so smoothly that other people are hardly aware of it.

Spoken production

I can use simple phrases and sentences to describe where I live and people I know.

I can use a series of phrases and sentences to describe in simple terms my family and other people, living conditions, my educational background and my present or most recent job.

I can connect phrases in a simple way in order to describe experiences and events, my dreams, hopes and ambitions. I can briefly give reasons and explanations for opinions and plans. I can narrate a story or relate the plot of a book or film and describe my reactions.

I can present clear, detailed descriptions on a wide range of subjects related to my field of interest. I can explain a viewpoint on a topical issue giving the advantages and disadvantages of various options.

I can present clear, detailed descriptions of complex subjects integrating sub-themes, developing particular points and rounding off with an appropriate conclusion.

I can present a clear, smoothly-flowing description or argument in a style appropriate to the context and with an effective logical structure which helps the recipient to notice and remember significant points.

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W r i t i n g

I can write a short, simple postcard, for example sending holiday greetings. I can fill in forms with personal details, for example entering my name, nationality and address on a hotel registration form.

I can write short, simple notes and messages. I can write a very simple personal letter, for example thanking someone for something.

I can write simple connected text on topics which are familiar or of personal interest. I can write personal letters describing experiences and impressions.

I can write clear, detailed text on a wide range of subjects related to my interests. I can write an essay or report, passing on information or giving reasons in support of or against a particular point of view. I can write letters highlighting the personal significance of events and experiences.

I can express myself in clear, well-structured text, expressing points of view at some length. I can write about complex subjects in a letter, an essay or a report, underlining what I consider to be the salient issues. I can select a style appropriate to the reader in mind.

I can write clear, smoothly-flowing text in an appropriate style. I can write complex letters, reports or articles which present a case with an effective logical structure which helps the recipient to notice and remember significant points. I can write summaries and reviews of professional or literary works.