Pubblicazioni

PUBBLICAZIONI

 

  1. Mitochondrial disfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid. M Rizzardini, M.Lupi, S. Bernasconi, A. Mangolini, L. Cantoni. J. Neurol Sci. 2003; 15;207:51-8.

 

2.      Induction of hepatic heme oxygenase-1 by diclofenac in rodens: role of oxidative stress and cytochrome P-450 activity. L. Cantoni, R. Valaperta, X. Ponsoda, J. V. Castell, D. Barelli, M. Rizzardini, A. Mangolini, L. Hauri, P. Villa. J. Hepatol. 2003; 38:776-83.

 

3.      Hyperforin contributes to the hepatic CYP3A-inducing effect of Hypericum perforatum extract in the mouse. L.Cantoni, M. Rozio, A. Mangolini, L. Hauri, S. Caccia. Toxicol Sci. 2003;75:25-30.

 

4.      Molecular basis for motor neuron selective damage induced by mutated SOD1: distribution of the G93A mutant of SOD1 in mitochondria and mitochondrial structural alterations in motor neuronal-like and in non-neuronal cellular models of ALS. Raimondi A,. Mangolini A, Vanoni C, Francolini M, Rizzardini M, Bendotti C, Cantoni L, Pietrini G. Amyotrophic Lateral Scler Other Mot Neuron Disord. 2003;4 (Suppl 1):150-151.

 

5.      Mutant G93A SOD1 increases mitochondrial dysfunction and death after inhibition of the electron transport chain in a cellular model of FALS. Rizzardini M, Mangolini A, Ubezio P, Lupi M, Conforti L, Cantoni L. Amyotrophic Lateral Scler Other Mot Neuron Disord. 2003;4 (Suppl 1):151-152.

 

6.      Low levels of ALS-linked Cu/Zn superoxide dismutase increases the production of reactive oxygen species and causes mitochondrial damage and death in motor neuron-like cells. M. Rizzardini, A. Mangolini, M. Lupi, P. Ubezio, C. Bendotti and L. Cantoni. J Neurol Sci. 2005;232:95-103.

 

7.      Tetracicline-regulated gene expression in the NSC-34 cell line for investigation of motor neuron diseases. E.Babetto, A.Mangolini, M. Rizzardini, M. Lupi, L. Conforti, P. Rosmini, A. Poletti, L. Cantoni. Molecular brain research. 2005;140(1-2):63-72.

 

8.      CYP3A-inducing effect of hyperforin and derivatives in rodents. L.Cantoni, M.Rozio, A.Mangolini, S.Caccia. Pharmacologyonline 2005;3:19-29 (www.pharmacologyonline.unisa.it).

 

9.      Neurodegeneration induced by complex I inhibition in a cellular model of familial amyotrophic lateral sclerosis. M. Rizzardini,M. Lupi, A.Mangolini, E. Babetto, P. Ubezio, L.Cantoni. Brain Res Bull. 2006 28;69(4):465-74.

 

10.  Cell culture models to investigate the selective vulnerability of moneuronal mitochondria to familial ALS-linked G93ASOD1. A. Raimondi A .Mangolini, M. Rizzardini, S. Tartari, S. Massari, C. Bendotti, M. Francolini, N. Borgese, L. Cantoni, G. Pietrini. Eur J Neurosci 2006;24:387-399.

 

11.  Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells. Banzi M, Aguiari G, Trimi V, Mangolini A, Pinton P, Witzgall R, Rizzuto R, del Senno L. Biochem Biophys Res Commun. 2006;350(2):257-62

 

12.  Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells. Aguiari G,Trimi V, Bogo M, Mangolini A, Szabadkai G, Pinton P, Witzgall R, harris PC, Borea PA, Rizzuto R, dl Senno L. Cell Proll; Cell Prolif. 2008; 41(3):554-73.

 

POSTERS

 

1.      An inducible cellular model to unreveal G93A-mutant superoxide dismutase 1 toxicity.

E. Babetto, A. Mangolini, L. Conforti, M. Rizzardini, P. Bigini and L. Cantoni.

41° Annual Meeting of the Italian Association of Neuropathology, 31° Annual Meeting of the Italian Association for research of the aging brain. Saluzzo (To) 26-28 Maggio 2005.

 

  1. A tetracycline-regulated cell line for the study of motor neuron diseases.

E. Babetto, A. Mangolini, M. Rizzardini, M. Lupi, L. Conforti, A. Poletti, P. Rusmini, L. Cantoni.

II° Meeting on the molecular mechanisms of neurodegeneration. Milano, 7-10/05/05

 

  1. Prolonged starvation induces apoptosis in HEK293 cells with deficiency of polycystin-1 generated by siRNA interfering.

G.Aguiari, M.Zanetti, A.Mangolini, V.Trimi, L. del Senno.

50° Congresso Nazionale SIB, Riccione, 27-30 Settembre 2005.

 

  1. Abnormal Ca2+ signalling, proliferation and apoptosis in different PKD-like kidney cells generated by PKD1, PKD2 and PKHD1 siRNA interfering.

A.Mangolini, G Aguiari, R Rizzuto, L del Senno.

First meeting of biomedical PhD programs, Ferrara, 20-21Febbraio 2006.

 

5.  Inhibition of PKHD1 expression by rna interference affects calcium signaling with effects on cell cycle in human kidney cells

A.Mangolini1, G.Aguiari1, L.del Senno1.

51° Congresso Nazionale SIB, Riccione, 28 Settembre-01 ottobre 2006.

 

6.  Deficiency of polycystin-1 leads to up regulation of adenosin A3 receptor expression in human kidney cell lines: possibile modulation of cell proliferation by specific receptor agonist.

     G.Aguiari, K.Varani, M.Bogo, A.Mangolini, C.Durante, P.A. Borea, L del Senno.

     53° Congresso Nazionale SIB, Riccione, 23-26 Settembre 2008.

    

7.  siRNA-mediated downregulation of PKD1 and PKHD1 genes: different effects on calcium homeostasis and cell proliferation.

A.Mangolini, G.Aguiari and L. del Senno.

     53° Congresso Nazionale SIB, Riccione, 23-26 Settembre 2008.