Curriculum

 

First name:                 CLAUDIO
Last name:                 TRAPELLA
Place of birth:            Ferrara
Date of birth:             December 27th 1972
Residence:                  Via Ungaretti, 9  I-44100-Ferrara
 
June 15th, 1990 – July 31st , 1990: Stage business at the quality control laboratories of the chemical farm “ENICHEM” in Ferrara on the subject: Quality control of plastic and industrial waste through technical gas cromatography and viscosimetry”.
 
July 1991: Diploma as chemical expert achieved at the “N. Copernico” Technical Institute of Ferrara with the vote of 46/60
 
July 20th, 1995: Biotecnology degree, with full marks and honours, achieved in the University of Ferrara discussing the thesis : “Synthesis and cytotoxicity studies of bioactive compounds from Melodorum Fruticosum (Annonaceae)”. The thesis work has been developed at the laboratories of Organic Chemistry of the Department of Pharmaceutical Sciences of the University of Ferrara under the guide of Prof. V. Zanirato.
 
October 2nd, 1996 – April 30th, 1997: Education grant (CARIFE’) at the Department of Biochemistry and Molecular Biology of the University of Ferrara on the subject: Development of a new methodology of in situ RT-PCR”.
 
October 25th , 1999: Full honours degree in Chemistry and Pharmaceutical Technology (Italian CTF) achieved at the University of Ferrara discussing the thesis: “Studies toward the synthesis of Eleuthesides” developed in the Organic Chemistry laboratories of the Department of Pharmaceutical Sciences, under the supervision of Prof. G.P. Pollini.
 
February 12th, 2003 PhD in Pharmaceutical Science achieved at the Department of Pharmaceutical Science of the University of Ferrara discussing a thesis entitled “Synthesis of non-peptide antagonists of the ORL-1 receptor”. I spent my last year of PhD working in the laboratory of organic chemistry of Cambridge University under the supervision of Prof S. Ley.
 
March 2003 Fellow from the SPINNER (FSE).
 
June 2003- December 2005: CEO of UFPeptides s.r.l. Spin-off company of the University of Ferrara.
 
March 2004-March 2006. Research fellow at the department of Pharmaceutical Science of University of Ferrara under the guidance of Prof. S. Salvadori for the synthesis of 1,3,4 trisubstituted piperidine.
 
From January 2006 till December 2007 contractors for UFPeptides s.r.l. using a found PRRIITT Regione Emilia Romagna 2005-2007 to develop solid phase synthesis and mass spectrometry analysis.
 
March 2008. Research fellow at the Department of Pharmaceutical Science of the University of Ferrara under the guidance of Prof. S. Salvadori for the synthesis of NOP ligands (agonists and antagonists).
 
November 17th , 2008: Full honours degree in Medical-Pharmaceutical Biotechnology achieved at the University of Ferrara discussing the thesis: “Synthesis of non peptide agonists of the Nociceptin Orphanin F/Q receptor” developed in the Medicinal Chemistry laboratories of the Department of Pharmaceutical Sciences, under the supervision of Prof. S. Salvadori.
 
Congress and seminars
 
 
1.         C. Trapella “Synthesis of J-113397 a new potent and selective antagonist of ORL-1 receptor” (Ferrara, “Bayer Day”, 18th September 2001) 
 
2.         C. De Risi, G.P. Pollini, C. Trapella, I. Peretto, S. Ronzoni, G.A.M. Giardina “A new approach at the synthesis of 1-[(3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one
 (J-113397), first non-peptidic antagonist of the ORL-1 receptor” (Riccione, “1st Sigma Aldrich Young Chemists Symposium”, 18th-19th October 2001)
 
3.         C. Trapella “Message/Address sequence modifications of Nociceptin/Orphanin FQ generate new higly potent ligands for the NOP receptor” (Camerino, “VIII Monothematic Meeting on Nociceptin/Orphanin FQ”, 15th-16th September 2003).
 
 
 
Specialization School
 
 
1.         XXV° Summer Course “A. Corbella” (Organic Synthesis Seminar), Gargnano (Bs) – 12th-16th June 2000 -
 
2.                     XXVI° Summer Course “A. Corbella” (Organic Synthesis Seminar), Gargnano (Bs) – 18th- 22th June 2001 -
 
3.         XX° Advanced Course in Pharmaceutical Chemistry and National PhD Seminar “E. Duranti”, Urbino- 2nd-6th July 2000 -
 
4.         XXI° Advanced Course in Pharmaceutical Chemistry and National PhD Seminar “E. Duranti”, Urbino- 1st-6th July 2001 –
 
5.         XXII° Advanced Course in Pharmaceutical Chemistry and National PhD Seminar “E. Duranti”, Urbino- 1st-5th July 2002 – – Presentation of a poster entitled:: “Synthesis of J-113397 a non peptidic antagonist of ORL-1 receptor”.
 
6.         Merck’s lecture, 20th-24th September 2002, Department of Chemistry of the University of Cambridge (UK).
 
7.         XXVIII° Summer Course “A. Corbella” (Organic Synthesis Seminar), Gargnano (Bs) – 16th- 20th June 2003 -
 
8.               Polish-Austrian-German-Hungarian-Italian Joint meeting on Medicinal Chemistry, 15th-18th October 2003, Kracov (Poland).
 
9.               XXIX° Summer Course “A. Corbella” (Organic Synthesis Seminar), Gargnano (Bs) – 14th- 18th June 2004 -
 
10.            XXX° Summer Course “A. Corbella” (Organic Synthesis Seminar), Gargnano (Bs) – 13th- 17th June 2005 -. Oral presentation entitled: “A new synthetic approach to 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-benzimidazol-2-one (J-113397), the first non-peptide NOP receptor antagonist.
 
11.            IASOC 2006 (Ischia Advanced School of Organic Chemisry) Ischia (Naples) 16th-21st September 2006.
 
12.            XIII° Meeting SERF,(HSMC) Heterocyclic Structure in Medicinal Chemistry, Palermo (Italy) 18th-21st May 2008.
 
13.            2nd European Chemistry Congress Turin (Italy) 16th-20th September 2008.
 
Research and professional experience
 
2003 Professor responsible of Laboratory of chemistry biotecnology at the University of Ferrara.
 
2004 Professor responsible of Laboratory of chemistry biotecnology at the University of Ferrara.
 
2005 Professor responsible of Laboratory of chemistry biotecnology at the University of Ferrara.
 
2006 Professor responsible of Laboratory of chemistry biotecnology at the University of Ferrara.
2007 Professor responsible of Laboratory of chemistry biotecnology at the University of Ferrara.
 
2008 Professor responsible of Laboratory of chemistry biotecnology at the University of Ferrara.