Pubblicazioni

Sforza F., Nicoli, F., Gallerani E., Finessi V., Reali E., Cafaro A., Caputo, A., Ensoli B.,Gavioli R. The HIV-1 Tat protein affects the programming and functionality of human CD8+ T cells by modulating the expression of T-box transcription factors. AIDS 28: 1729-1738, 2014

Bosè F., Capsoni F., Molteni S., Raeli L., Diani M., Altomare A., Garavaglia M., Garutti C.,  Frigerio E., Banfi G., Altomare G.,  Reali E. Differential expression of IL-2 by anti-CD3 stimulated PBMC in patients with psoriatic arthritis and patients with cutaneous psoriasis. Clin. Exp. Dermatol. 39:385-390,  2014.

Bosè F., Petti L., Diani M., Moscheni C., Molteni S., Altomare A., Rossi R., Talarico D., Fontana R., Russo V., Altomare G, Reali E.  Inhibition of CCR7/CCL19 axis in lesional skin is a critical event for clinical remission induced by TNF-blockade in psoriasis patients. Am. J. Pathol., 183: 413-412 2013.

Caprioli F., Bosè F., Rossi R., Petti L., Viganò C., Ciafardini C., Raeli L, Basilisco G., Ferrero S., Pagani M, Conte D., Altomare G., Monteleone G., Abrignani S., Reali E. Reduction of CD68⁺ macrophages and decreased IL-17 expression in intestinal mucosa of patients with Inflammatory Bowel Disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy. Inflamm. Bowel Dis. 19:729-739, 2013.

Molteni S., Reali E. Biomarkers in the pathogenesis, treatment and diagnosis of psoriasis. Psoriasis: Targets and Therapy 2: 55–66, 2012

Capsoni F., Ongari A.M., Reali E., Altomare G. The protein kinase C-selective inhibitor AEB071 (Sotrastaurin) modulates migration and superoxide anion production by human neutrophils “in vitro”. Int. J. Immunopathol. Pharmacol. 25:617-626, 2012.

Cantù C., Bosè F., Bianchi P., Reali E., Ottolenghi S., Witke W., Spinardi L., Ronchi A. Defective Erythroid maturation in BALB7c gelsolin mutant mice. Haematologica, 97:980-8, 2012

Bosè, F., Raeli, L., Garutti, C., Frigerio, E., Cozzi, A., Crimi, M., Caprioli, F., Scavelli, R., Altomare, G., Geginat, J., Abrignani, S., Reali, E., Dual role of anti-TNF therapy: enhancement of TCR-mediated T cell activation in peripheral blood and inhibition of inflammation in target tissues.  Clin.Immunol. 139:164-176, 2011.

Capsoni F, Ongari AM, Reali E, Catania A. Melanocortin peptides inhibit urate crystal-induced activation of phagocytic cells. Arthritis Res. Ther. 11: R151, 2009.

Voltan R, Castaldello A, Brocca-Cofano E, De Michele R, Triulzi C, Altavilla G, Tondelli L, Laus M, Sparnacci K, Reali E, Gavioli R, Ensoli B, Caputo A. Priming with a very low dose of DNA complexed with cationic block copolymers followed by protein boost elicits broad and long-lasting antigen-specific humoral and cellular responses in mice. Vaccine. 27 :4498-507, 2009.

Zeytin, H. Reali, E.,  Zaharoff D.A.,  Rogers C.J., Schlom J., Greiner J.W. Targeted delivery of murine Interferon-g using a recombinant Fowlpox virus:  NK cell recruitment to regional lymph nodes and priming of tumor-specific host immunity . J. Interferon Cytokine Res. 28:73-87, 2008.

Reali, E., Canter, D., Zeytin, H., Schlom, J., Greiner J.W. Comparative study of Avipox-GM-CSF versus recombinant GM-CSF protein as immune adjuvants with different vaccine platforms.  Vaccine 23: 2909-2921, 2005.

Schmitz, J., Reali, E., Hodge, J.W., Patel, A., Davis, G., Schlom, J., Greiner J.W. Identification of an Interferon-g-inducible Carcinoembryonic antigen (CEA) CD8+ T-Cell epitope, which mediates tumor killing in CEA transgenic mice. Cancer Res. 62, 5058-5064, 2002.

Reali, E., Greiner, J. W., Corti, A., Gould, H. J., Bottazzoli, F., Paganelli, G.,   Schlom,  J., Siccardi, A. G. IgEs targeted on tumor cells: therapeutic activity and potential in the design of tumor vaccines. Cancer Res. 61: 5517-5522, 2001.

Guttinger. M, Guidi, F., Chinol, M., Reali, E., Veglia, F., Viale, G., Paganelli, G., Corti, A., Siccardi, A.G. Adoptive Immunotherapy by Avidin-driven cytotoxic T lymphocyte-tumor bridging. Cancer Res. 60: 4211-4215, 2000.

Reali, E., Guerrini, R., Marastoni, M., Tomatis, R., Masucci, M. G., Traniello, S.,  Gavioli, R. A single specific amino acid residue in peptide antigens is sufficient to activate memory CTL: potential role of cross-reactive peptides in memory T cell maintenance. J. Immunol. 162: 106-13, 1999.

Aguiari, G. L., Bozza, A., Piva, R., Volinia, S., Reali, E., Maestri, I., Magri, E., Cavazzini, L., del Senno, L. Expression of protein fragments from the human PKD1 gene and production of rabbit polyclonal antibodies to the recombinant proteins. Contrib. Nephrol. 122: 49-52, 1997.

Marastoni, M., Tomatis, R., Reali, E., Gavioli, R. Synthetic peptides as a tool for studying the selection and presentation of antigens by MHC class I molecules. Curr. Topics in Pept.Prot. Res. 2: 41-51, 1997.

Reali, E., Guerrini, R., Moretti, S., Spisani, S., Lanza, F., Tomatis, R., Traniello, S., Gavioli, R. Polymorphonuclear neutrophils pulsed with synthetic peptides efficiently activate memory cytotoxic T lymphocytes. J. Leukoc. Biol. 60: 207-13, 1996.

Cavicchioni, G., Breveglieri, A., Boggian, M., Vertuani, G., Reali, E., Spisani, S. The importance of the peptide bond at position 2 in HCO-Met-Leu-Phe-OMe analogues as shown by studies on human neutrophils. J. Pept. Sci. 2: 135-40, 1996

Reali, E., Guerrini, R., Giori, B., Borghi, M., Marastoni, M., Tomatis, R., Traniello, S., Masucci, M. G., Gavioli, R. Activation of epitope-specific memory cytotoxic T lymphocyte responses by synthetic peptides. Clin. Exp. Immunol. 105: 369-75, 1996

Cavicchioni, G., Breveglieri, A., Reali, E., Spisani, S. Synthesis and biological activity of a conformationally constrained chemotactic gamma-lactam formyl tetrapeptide. Arzneimittelforschung. 46: 964-6, 1996.

Spisani, S., Breveglieri, A., Reali, E., Scatturin, A., Vertuani, G., Cavicchioni, G. Biological properties of the formylated fMLP analog containing an iodomethylated methionine residue. Prot. Pept. Lett. 2: 415-418, 1995.

Reali, E., Spisani, S., Gavioli, R., Lanza, F., Moretti, S., Traniello, S. IL-8 enhances antibody-dependent cellular cytotoxicity in human neutrophils. Immunol. Cell Biol. 73: 234-8, 1995.

Gavioli, R., Zhang, Q. J., Marastoni, M., Guerrini, R., Reali, E., Tomatis, R., Masucci, M. G., Traniello, S. Effect of anchor residue modifications on the stability of HLA-A11/peptide complexes. Biochem. Biophys. Res. Commun.206: 8-14, 1995.

Reali, E., Giuliani, A. L., Spisani, S., Moretti, S., Gavioli, R., Masucci, G., Gambari, R., Traniello, S.  Interferon-gamma   enhances   monoclonal   antibody 17-1A-dependent neutrophil cytotoxicity toward colorectal carcinoma cell line SW11-16. Clin. Immunol. Immunopathol. 71: 105-12, 1994.

Ferretti, M. E., Spisani, S., Pareschi, M. C., Buzzi, M., Cavallaro, R., Traniello, S., Reali, E., Torrini, I., Paradisi, M. P., Zecchini, G. P. Biondi, C. Two new formylated peptides able to activate chemotaxis and respiratory burst selectively as tools for studying human neutrophil responses. Cell Signal. 6: 91-101, 1994.

Marastoni, M., Salvadori, S., Scaranari, V., Spisani, S., Reali, E., Traniello, S., Tomatis, A. Synthesis and activity of new linear and cyclic peptide T derivatives. Arzneimittelforschung. 44: 1073-6, 1994.

Giuliani, A. L., Spisani, S., Cavalletti, T., Reali, E., Melchiorri, L., Ferrari, L., Lanza, F., Traniello, S. Fibroblasts increase adhesion to neutrophils after stimulation with phorbol ester and cytokines. Cell Immunol. 149: 208-22, 1993.

Marastoni, M., Salvadori, S., Balboni, G., Scaranari, V., Spisani, S., Reali, E., Traniello, S., Tomatis, R. Structure-activity relationships of cyclic and linear peptide T analogues. Int J Pept Protein Res. 41: 447-54, 1993.

Reali, E., Mellstedt, H., Masucci, G. GM-CSF augments the IL-4-induced cytotoxic activity of human mononuclear cells in the presence of the mouse monoclonal antibody 17-1A. Cancer J. 6: 116-122, 1993.

Cavalletti, T., Reali, E., Marangoni, C., Bader, S., Traniello, S. Effect of neutral shampoos on cultures of human fibroblasts. ATLA-Alte. Lab. Anim. 19: 87-93, 1991

Marastoni, M., Salvadori, S., Balboni, G., Scaranari, V., Spisani, S., Reali, E., Giuliani, A. L., Tomatis, R. Cyclic peptide T analog with high chemotactic activity. Eur. J. Med. Chem. 27: 383-391, 1992.

Book Chapters:

Abrignani S., Reali E., Houghton M., De Francesco R. Hepatitis C Vaccines. In: Vaccines, S.A. Plotkin, W. Orenstein, and P. Offit (eds.); 6th Edition, Philadelphia: Elsevier, 1074-1084, 2012

Reali, E., Houghton, M., Abrignani, S. Vaccination against the hepatitis C virus.  In: Vaccines, S.A. Plotkin, W. Orenstein, and P. Offit (eds.); 5th Edition, Philadelphia: Elsevier, 1187-1199, 2008.