CURRICULUM VITAE

PIERA BOSCHETTO
Associate Professor in Occupational Medicine

Department of Medical Sciences
Section of Occupational Medicine
University of Ferrara
Via Fossato di Mortara, 64B
44121 Ferrara - Italy
Phone. +39 0532 455565
Fax. +39 0532 205066
e-mail: bsp@unife.it


1. BORN and RESIDENCE

-Born in Follina (Treviso) on 21 January 1958; living in Treviso, Via Zorzi 30, 31100; mobile +39-347-0159879;

2. CITIZENSHIP AND MARITAL STATUS

-Italian

-Married to Luigino Dal Vecchio

3. DEGREES

-Degree in Medicine and Surgery, 110/110 summa cum laude, 1983, University of Padua

-Board in Occupational Medicine, 70/70 summa cum laude, 1988, University of Padua

-PhD in Respiratory Diseases, 1992, University of Milan and Padua

-Board in Respiratory Diseases, 50/50 summa cum laude, 2001, University of Ferrara

4. PROFESSIONAL EXPERIENCE:

1984 – 1991 University of Padua, Institute of Occupational Medicine. Fellowship as a support member for a research team

1987 – 1988 12 months at Brompton Hospital London, Cardio-Thoracic Institute. Scientist

1991 – 1993 University of Ferrara, Institute of Infectious and Respiratory Diseases. Fellowship as a support member for a research team

1993 – 1999 National Health Service, Occupational Health Service Department in San Donà (Venice) and Treviso. Occupational Health Adviser and Consultant

1999 – 2010 University of Ferrara, Section of Occupational Medicine. Researcher

2010 to Date, University of Ferrara, Section of Occupational Medicine. Associate Professor

2005 to Date, University of Ferrara, Occupational Medicine Service. Director

2017 to Data, University of Ferrara, School of Specialization in Occupational Medicine. Director

5. TEACHING ACTIVITY:

-Padua University Hospital, Nurse School, “Principles of Hygiene, Epidemiology and Prophylaxis”, 1984-85

-Regione Veneto, U.L.S.S. n. 7: Conegliano Nurse School, “Social Legislation”, 1984-85

-University of Padua, Respiratory Pathophysiology, “Bronchoalveolar Lavage Techniques”, 1986-1988.

-University of Padua, Respiratory Pathophysiology, "Microvascular permeability in lung of rat: Techniques”, 1988-1989.

-University of Ferrara, School of Respiratory Diseases, “Clinical Methodology”, 1992-1994

-University of Ferrara, teacher at CME courses, December 2002

-University of Ferrara, Nurses and Obstetrics School, “Occupational Astma”, 2002 – to date

-University of Ferrara, School for Dieticians, Dentist, Nurses, Obstetrics, Speech Therapy, Optic, “Workplace Safety”, 2003-2005.

-University of Ferrara, Dentistry School, Workplace Safety, 2004-2005.

-University of Ferrara, Physiotherapy School, “Occupational Medicine”, 2004.

-University of Ferrara, Nurses and Obstetrics School, “Occupational Medicine”, 2004- 2005.

-University of Ferrara, School of Medicine, “Occupational Medicine”, 2004 to date.

-University of Bologna e Ferrara, School of Specialization in Occupational Medicine, “Occupational Medicine” 2001 – to date

-University of Ferrara, School of Specialization in Occupational Medicine, “Occupational Medicine” 2017 – to date


6. GRANTS

-Italian National Research Council, 2000, 2009, 2010, 2011, 2012, 2013

-Italian Ministry of Education, 2003, 2006

-European Union, "FP7-HEALTH-2007-A" 2007-2012 (EvA)

-European Union, "FP7-HEALTH-2011-2017 (AirPROM)


7. EDITORIAL BOARDS OF SCIENTIFIC JOURNALS

OCCASIONAL REFEREE

-Allergy

-American Journal of Respiratory and Critical Care Medicine

-European Journal of Allergy and Clinical Immunology

-European Respiratory Journal

-International Archives of Allergy and Immunology

8. SCIENTIFIC SOCIETIES

-American Thoracic Society, 2003-2009

-European Respiratory Society, 2003 to date

-Società Italiana di Medicina del Lavoro ed Igiene Industriale, 2003 to date


9.PUBLICATIONS

-PUBLICATIONS IN PEER-REVIEWED JOURNALS LISTED IN THE CURRENT CONTENTS :84
-BOOK CHAPTERS:15
-MONOGRAPHIES:3

H-index:29 (Scopus, 2018)
Citazioni totali:3068 (Scopus, 2018)


A) MONOGRAPHIES

1. Translation of the monograph: Postma DS, Siafakas NM. Broncopneumopatia cronica ostruttiva Eur.Respir.Mon. 1999; 3: 1-83.

2. Mapp CE, Boschetto P.:Asma professionale. Monografia “Rapporto sull’asma 2001” a cura di De Palma M, Fabbri LM, Grassi C, Syntagma 2001: 265-269.

3. Boschetto P, Miotto D, Mapp CE,: Women and asthma. Eur. Respir. Mon: Buist S, Mapp CE. 25, June 2003; 8: 90-102.

B) BOOK CHAPTERS

1.Traduzione dall'inglese del cap.30 del Trattato di Medicina Respiratoria, Murray-Nadel, ed. Piccin, Padova, vol.I, pp. 707-722.

2.Fabbri LM, Papi A, Boschetto P, Ciaccia A: Management of bronchial asthma. Summary of International guidelines. In Melillo G, O’ Byrne PM, and Marone G (Eds). Proceedings of the third international meeting on “Respiratory allergy. Advances in clinical immunology and pulmonary medicine”. Excepta Medica 1993; pp195-203.

3.Fabbri LM, Papi A, Boschetto P, Ciaccia A: Management of bronchial asthma. In Kummer (Eds). Asthma. Immunopathology and immunotherapy. Springer Verlag, Wien 1993; 162-174.

4.Boschetto P, Papi A, Ciaccia A, Fabbri LM: Neutrophils in asthma. In Busse W, Holgate ST (Eds). Asthma and rhinitis. Blackwell Scientific, Cambridge, 1995; 383-8.

5.Papi A, Boschetto P, Ciaccia A, Fabbri LM: Eosinophils and non atopic asthma. In Nadel JA, Venge P, and Pozzi E (Eds). Proceedings of the Forth Meeting on Pathophysiology of Pulmonary Cells. Masson, Milan, 1995; 141-154.

6.Fabbri LM, Boschetto P, Caramori G, Maestrelli P: Neutrophils and asthma. In Holgate ST, Busse W (Eds). Inflammatory mechanisms in asthma. NewYork, Marcel Dekker 1998; pp.287-322.

7.Fabbri LM, Boschetto P, Caramori G, Mapp CE: Pathophysiology. In Bernstein L, Chan-Yeung M, Malo J-L, Bernstein D, (Eds). Asthma in the workplace. NewYork, Marcel Dekker 1999; pp.81-110.

8.Papi A, Boschetto P, Caramori G, Fabbri LM: Neutrophyls and asthma. In Busse W. Holgate S.T. (Eds). Asthma and rinhitis. London, Blackwell Scientific Publications 2000; pp.518-530.

9.Maestrelli P, Boschetto P, Carta P, Corradi M, De Zotti R, Di Lorenzo L, Ferrari M, Guarnieri G, Imbriani M, Innocenti A, Mapp CE, Murgia N, Muzi G, Patrini L, Quercia A, Riboldi L, Romano C., Soleo L. Serie Editors: Apostoli P, Bertazzi PA, Isolani L, Imbriani M, Abbritti G. Linee guida per la formazione continua e l’accreditamento del medico del lavoro. Linee guida per la sorveglianza sanitaria di lavoratori esposti ad irritanti e tossici per l’apparato respiratorio 2009. [Pubblicazione on-line]. pp.3-157.

10.Maestrelli P, Boschetto P, Dykewicz M.S: Occupational Allergy. In Holgate S.T. Oxford Elsevier (Eds). Allergy 2012; Cap. 15 pp.305-379.

11.Maestrelli P, Boschetto P. Metodiche non invasive di misura dell’infiammazione broncopolmonare. In EdiSES S.r.l. (Eds). Trattato di malattie respiratorie, 2013; Cap 14 pp. 152-157.

12.Baraldi E, Boner AL, Boschetto P, Clini EM, Confalonieri M, Cremona G, Luppi F, Marchioni A, Marietta M, Monelli M, Morandi U, Pardi R, Piacentini G, Rea F, Richeldi L, Roversi P, Rossi R, Schiavina M, Spagnolo P, Torregiani C, Verduri A, Vitulo P, Fabbri LM: Altri problemi di patologia respiratoria. In Rugarli C. Milano, Elsevier (Eds). Medicina Interna Sistematica 2010; Cap. 21 pp.501-566. UPDATED IN 2015

13.Baraldo S, Boschetto P, Corbetta L, Corradini P, Maestrelli P, Maffessanti M, Mapp CE, Pardi R, Patelli M, Poletti V, Rossi G, Saetta M, Spanevello A, Torricelli P, Turato G, Zompatori M, Fabbri LM: Introduzione generale alle malattie respiratorie. In Rugarli C. Milano, Elsevier (Eds). Medicina Interna Sistematica 2010; Cap 15 pp. 339-369. UPDATED IN 2015

14.Boschetto P, Mapp CE, Maestrelli P: Malattie respiratorie di origine professionale e/o ambientale. In Rugarli C. Milano, Elsevier (Eds). Medicina Interna Sistematica 2010; Cap 19 pp. 471-479. UPDATED IN 2015

15.Boschetto Piera, Malerba Mario, Poletti Venerino, Sanduzzi Zamparelli Alessandro. Manuale di pneumologia. In: (a cura di): Enrico Maria Clini Girolamo Pelaia, Manuale di pneumologia: Biomarcatori nelle malattie del polmone. Edises srl 2017; vol.7,pp.73-91.

C) PUBLICATIONS IN PEER-REVIEWED JOURNALS LISTED IN THE CURRENT CONTENTS

1. Mapp CE, Dal Vecchio L, Boschetto P, Fabbri LM. Combined asthma and alveolitis due to diphenylmethane diisocyanate (MDI) with demonstration of no crossed respiratory reactivity to toluendiisocyanate (TDI). Ann Allergy 1985; 54:424-9.

2. Mapp CE, Dal Vecchio L, Boschetto P, De Marzo N, Fabbri LM. Toluene diisocyanate-induced asthma without airway hyperresponsiveness. Eur J Respir Dis 1986; 68:89-95.

3. Fabbri LM, Boschetto P, Zocca E, Milani GF, Pivirotto F, Burlina A, Mapp. Bronchoalveolar neutrophilia during late asthmatic reactions induced by toluene diisocyanate (TDI). Am Rev Respir Dis 1987; 136: 36-42.

4. Boschetto P, Zocca E, Bruchi O, Cappellazzo G, Milani GF, Pivirotto F, Mapp CE, Fabbri LM. Importance of airway inflammation for late asthmatic reactions induced by toluene diisocyanate in sensitized subjects. Advances in Prostaglandin, Thromboxane, and Leukotriene Research 1987; 17b: 1080-1084.

5. Boschetto P, Fabbri LM, Zocca E, Milani GF, Pivirotto F, Dal Vecchio L, Plebani A, Mapp C.E.. Prednisone inhibits late asthmatic reactions and airway inflammation induced by toluene diisocyanate in sensitized subiects. J Allergy Clin Immunol 1987: 80: 261-267.

6. Mapp CE, Boschetto P, Dal Vecchio L, Crescioli S, De Marzo N, Paleari D, Fabbri LM. Protective effect of antiasthma drugs on late asthmatic reactions and increased responsiveness induced by toluene-diisocyanate in sensitized subjects. Am Rev Respir Dis 1987; 136: 1403-7.

7. Mapp CE, Boschetto P, Zocca E, Milani GF, Pivirotto F, Tegazzin V, Fabbri LM. Pathogenesis of late asthmatic reactions induced by exposure to isocyanates. Bull Eur Physiopathol Respir 1987; 23: 583-6.

8. Mapp CE, Boschetto P, Dal Vecchio L, Maestrelli P, Fabbri LM. Occupational asthma due to isocyanates. Eur Respir J 1988; 1: 279-9.

9. Fabbri LM, Boschetto P, Zocca E, De Marzo N, Crescioli S, Maestrelli P, Mapp CE. Pathogenesis of bronchial hyperresponsiveness. Respiration 1988; 54 (SuppI ): 90-4.

10. Boschetto P, Milani GF, Pivirotto F, Zocca E, De Marzo N, Mapp CE, Fabbri LM. Lavaggio broncoalveolare nell' asma. Editoriale, Folia Allergol Immunol Clin 1989; 36: 1-7.

11. Boschetto P, Roberts NM, Rogers DF, Barnes PJ. Effect of anti-asthma drugs on microvascular leakage in guinea-pig airways. Am Rev Respir Dis 1989; 139: 416-21.

12. Rogers DF, Boschetto P, Barnes PJ. Plasma exudation: correlation between Evans Blue Dye and Radiolabelled Albumin in guinea pig airways in vivo. J Pharmacol Methods 1989; 21: 309-315.

13. De Marzo N, Di Blasi P, Boschetto P, Mapp CE, Sartore S, Fabbri LM. Airway smooth muscle biochemistry and asthma. Eur Respir J 1989; 2 Suppl.6: 473s-476s.

14. Boschetto P, Mapp CE, Fabbri LM. Neutrophils and Asthma. Eur Respir J 1989; Suppl.6: 456s-459s.

15. Mapp CE, Boschetto P, Picotti G, De Marzo N, Fabbri LM. Steroid and non-steroid anti-inflammatory agents in asthma. Eur Respir J 1989; Suppl. 6: 566s-567s.

16. Zocca E, Fabbri LM, Boschetto P, Masiero M, Milani GF, Pivirotto F, Mapp CE. Leukotriene B4 and late asthmatic reactions induced by toluene diisocyanate. J Appl Physiol 1990; 68: 1576-80.

17. Maestrelli P, Boschetto P, Zocca E, Crescioli S, Baroldi P, Mapp C, Fabbri LM. Venous blood platelets decrease during allergen-induced asthmatic reactions. Clinical and Experimental Allergy 1990; 20: 367-372.

18. Rogers DF, Alton EWFW, Aursudkij B, Boschetto P, Dewar A, Barnes PJ. Effect of platelet activating factor on formation and composition of airway fluid in the guinea-pig trachea. Journal of Physiology 1990; 431: 643-658.

19. Barnes PJ, Boschetto P, Rogers DF, Belvisi M, Roberts N, Chung KF, Evans TW. Effects of treatment on airway microvascular leakage. Eur Respir J 1990; 3, Suppl 12: 663s-671s.

20. Boschetto P, Rogers DF, Fabbri LM, Barnes PJ. Corticosteroid inhibition of airway microvascular leakage. Am Rev Respir Dis 1991; 143: 605-609.

21. Crescioli S, Spinazzi A, Plebani M, Pozzan M, Mapp CE, Boschetto P, Fabbri LM. Theophylline inhibits early and late asthmatic reactions induced by allergens in asthmatic subjects. Ann Allergy 1991; 66: 245-251.

22. Boschetto P, Musajo FG, Tognetto L, Boscaro M, Mapp CE, Barnes PJ, Fabbri LM. Increase in vascular permeability produced in rat airways by PAF: potentiation by adrenalectomy. Br J Pharmacol 1992; 105: 388-392.

23. Fabbri LM, De Rose V, Godard P, Boschetto P, Rossi GA. Guidelines and recommendations for the clinical use of bronchoalveolar lavage in asthma. Eur Respir Rev 1992; 2: 116-123.

24. Crescioli S, De Marzo N, Boschetto P, Spinazzi A, Plebani M, Mapp CE, Fabbri LM, Ciaccia A. Theophylline inhibits late asthmatic reactions induced by toluene diisocyanate in sensitized subjects. Eur J Pharmacol 1992; 228: 45-50.

25. Luzzatto G, Cella G, Boschetto P, Fabbri LM. Lack of increase of reduction in circulating platelet factor 4 and heparin-releasable platelet factor 4 in symptomatic patients with asthma. J Lipid Mediat 1993; 7: 151-154.

26. Mapp CE, Saetta M, Maestrelli P, Di Stefano A, Chitano P, Boschetto P, Ciaccia A, Fabbri LM. Mechanisms and pathology of occupational asthma. Eur Respir J 1994; 7: 544-554.

27. Di Stefano A, Turato G, Maestrelli P, Mapp CE, Ruggeri MP, Roggeri A, Boschetto P, Fabbri LM, Saetta M. Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa. Am J Respir Crit Care Med 1996; 153: 629-632.

28. Chitano P, Rado V, Di Stefano A, Papi A, Boniotti A, Zancuoghi G, Boschetto P, Romano M, Salmona M, Ciaccia A, Fabbri LM, Mapp CE. Effect of subchronic in-vivo exposure to nitrogen dioxide on lung tissue inflammation, airway microvascular leakage, and in-vitro bronchial muscle responsiveness in rats. Occupational and Environmental Medicine 1996; 53: 379-386.

29. Crescioli S, Dal Carobbo A, Maestrelli P, Boschetto P, Santagada T, Steinijans VW, Hurst TS, Parise G, Fabbri LM. Controlled-release theophylline inhibits early morning airway obstruction and hyperresponsiveness in asthmatic subjects. Ann Allergy Asthma Immunol 1996; 77: 1-5.

30. Di Giacomo GR, Boschetto P, Maestrelli P, Moro G. Asthma and rhinoconjunctivitis caused by rape flour: description of a clinical case. Med Lav 1998; 89: 226-31.

31. Papi A, Amadesi S, Chitano P, Boschetto P, Ciaccia A, Geppetti P, Fabbri LM, Mapp CE. Bronchopulmonary inflammation and airway smooth muscle hyperresponsiveness induced by nitrogen dioxide in guinea pigs. Eur J Pharmacol 1999; 374: 241-247.

32. Mapp CE, Boschetto P, Miotto D, De Rosa E, Fabbri LM. Mechanisms of occupational asthma. Ann Allergy Asthma Immunol 1999; 83: 645-664. Review.

33. De Marzo N, Jovine L, Rizzotti P, Cassetti P, Boschetto P, Miotto D, Saetta M, Maestrelli P, Mapp CE. Modification of serum proteins in guinea pigs immunized and challenged with toluene diisocyanates. Scand J Work Environ Health 2000; 26: 153-160.

34. Boschetto P, Jovine L, Chitano P, De Marzo N, Plebani M, Faggian D, Fabbri LM, Mapp CE. Serum-mediated relaxant response to toluene diisocyanate in isolated guinea pigs bronchi. Respir Med 2001; 95: 357-362.

35. Pozzato V, Padoan M, De Marzo N, Ferrarese S, Boschetto P, Fryer AA, Strange RC, Hemmingsen A, Spiteri MA, Mapp CE. Ruolo delle glutation-S-Transferasi (GSTs) nell’asma professionale indotto da isocianati. G Ital Med Lav Ergon 2001; 23: 276.

36. Miotto D, Hollemberg MD, Bunett NW, Papi A, Braccioni F, Boschetto P, Rea F, Zuin A, Geppetti P, Saetta M, Maestrelli P, Fabbri LM, Mapp CE. Expression of protease activated receptor –2 (PAR- 2) in central airways of smokers and nonsmokers. Thorax 2002; 57: 146-151.

37. Mapp CE, Fryer AA, De Marzo N, Pozzato V, Padoan M, Boschetto P, Strange RC, Hemmingsen A, Spiteri MA. Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates. J Allergy Clin Immunol 2002; 109: 867-872.

38. Turato G, Zuin R, Miniati M, Baraldo S, Rea F, Beghè B, Monti S, Formichi B, Boschetto P, Harari S, Papi A, Maestrelli P, Fabbri LM, Saetta M. Airway inflammation in severe chronic obstructive pulmonary disease: relationship with lung function and radiologic emphysema. Am J Respir Crit Care Med 2002; 166: 105-110.

39. Padoan M, Pozzato V, Simoni M, Zedda L, Milan G, Bononi I, Piola C, Maestrelli P, Boschetto P, Mapp CE. Long - term follow up of toluene diisocyanate-induced asthma. Eur Respir J 2003; 21: 637-640.

40. Caramori G, Romagnoli M, Casolari P, Bellettato C, Casoni G, Boschetto P, Fan Chung K, Barnes PJ, Adcock IM, Ciaccia A, Fabbri LM, Papi A. Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations. Thorax 2003; 58: 348-351.

41. Boschetto P, Miniati M, Miotto D, Braccioni F, De Rosa E, Bononi I, Papi A, Saetta M, Fabbri LM, Mapp CE. Predominant emphysema phenotype in chronic obstructive pulmonary disease patients. Eur Respir J 2003; 21: 450-454.

42. Boschetto P, Quintavalle S, Mazzetti L, Miotto D, Bononi I, Mapp CE, De Rosa E. Sostanza P nell’escreato di pazienti con broncopatia cronica ostruttiva ed esposizione professionale ad itrritanti respiratori. G Ital Med Lav Ergon 2003; 25: 129-130.

43. Miotto D, Ruggieri MP, Boschetto P, Cavallesco G, Papi A, Bononi I, Piola C, Murer B, Fabbri LM, Mapp CE. Interleukin-13 and -4 expression in the central airways of smokers with chronic bronchitis. Eur Respir J 2003; 22: 602-608.

44. Papi A, Casoni G, Caramori G, Guzzinati I, Boschetto P, Ravenna F, Calia N, Petruzzelli S, Corbetta L, Cavallesco G, Forini E, Saetta M, Ciaccia A, Fabbri LM. COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma. Thorax 2004; 59: 679-681.

45. Miotto D, Boschetto P, Bononi I, Zeni E, Cavallesco G, Fabbri LM, Mapp CE. Vasoactive intestinal peptide receptors in the airways of smokers with chronic bronchitis. Eur Respir J 2004; 24: 958-63.

46. Boschetto P, Miotto D, Bononi I, Faggian D, Plebani M, Papi A, Creminon C, De Rosa E, Fabbri LM, Mapp CE. Sputum substance P and neurokinin A are reduced during exacerbations of chronic obstructive pulmonary disease. Pulm Pharmacol & Ther 2005; 18: 199-205.

47. Mapp CE, Boschetto P, Maestrelli P, Fabbri LM. Occupational asthma. Am J Respir Crit Care Med 2005;172: 280-305.

48. Mapp CE, Boschetto P, Miotto D, De Rosa E. Asthma induced by isocyanates: a model of IgE-independent asthma. Acta Bio Medica 2005; 76: 15-19.

49. Quintavalle S, Mazzetti L, Zeni E, Lo Cascio N, Leprotti S, Ballerin L, Potena A, Mapp CE, De Rosa E, Boschetto P. Esposizione professionale ad agenti irritanti e sviluppo di broncopneumopatia cronica ostruttiva (BPCO). G Ital Med Lav Ergon 2005; 27: 370-372.

50. Mazzetti L, Murer B, Quintavalle S, Zeni E, Miotto D, Mapp CE, De Rosa E, Boschetto P. Lung cancer in a female non-smoker with occupational exposure to asbestos: a case report. Med Lav 2006; 97: 581-585.

51. Toffoletto F, Mosconi G, Frigeri G, Boschetto P. Efficacy in occupational medicine: proposals of the regional sections of SIMLII of Lombardy and Emilia Romagna. G Ital Med Lav Ergon 2006; 28 (Supp.1): 168-9.

52. Boschetto P, Quintavalle S, Miotto D, Lo Cascio N, Zeni E, Mapp CE. Chronic obstructive pulmonary disease (COPD) and occupational exposures. J Occup Med Toxicol 2006; 1:11.

53. Boschetto P, Quintavalle S, Zeni E, Leprotti S, Potena A, Ballerin L, Papi A, Palladini G, Luisetti M, Annovazzi L, Iadarola P, De Rosa E, Fabbri LM, Mapp CE. Association between markers of emphysema and more severe chronic obstructive pulmonary disease. Thorax 2006; 61: 1037-1042.

54. Mapp CE, Miotto D, Boschetto P. Occupational asthma. Med Lav 2006; 97: 404-409.

55. Miotto D, Boschetto P, Bononi I, Milani G, Legorini C, Cavallesco G, Lo Cascio N, Zeni E, Fabbri LM, Mapp CE. CC ligand 2 levels are increased in LPS-stimulated peripheral monocytes of patients with non-small cell lung cancer. Respir Med 2007; 8: 1738-1743.

56. Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE. Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Histopathology 2007; 51: 128-130.

57. Zeni E, Mazzetti L, Miotto D, Lo Cascio N, Maestrelli P, Querzoli P, Pedriali M, De Rosa E, Fabbri LM, Mapp CE, Boschetto P. Macrophage expression of IL-10 is a prognostic factor in non-small cell lung cancer. Eur Respir J 2007; 30: 627-32.

58. Beltrame D, Lo Cascio N, Miotto D, Mapp CE, De Rosa E, Boschetto P. Occupational exposure and chronic heart failure severity. G Ital Med Lav Ergon 2007;29(3 Suppl):438-9.

59. Casado B, Iadarola P, Pannell LK, Luisetti M, Corsico A, Ansaldo E, Ferrarotti I, Boschetto P, Baraniuk JN. Protein expression in sputum of smokers and chronic obstructive pulmonary disease patients: a pilot study by CapLC-ESI-Q-TOF. J Proteome Res 2007; 6: 4615-23.

60. Fabbri LM, Boschetto P, Mapp CE; Global Initiative for Chronic Obstructive Lung Disease; Global Initiative for Asthma Management and Prevention. COPD guidelines: the important thing is not to stop questioning. Am J Respir Crit Care Med. 2007; 176: 527-8.

61. Boschetto P, Zeni E, Mazzetti L, Miotto D, Lo Cascio N, Maestrelli P, Marian E, Querzoli P, Pedriali M, Murer B, De Rosa E, Fabbri LM, Mapp CE. Decreased heme-oxygenase (HO)-1 in the macrophages of non-small cell lung cancer. Lung Cancer 2008; 59:192-7.

62. Fabbri LM, Boschetto P, Mapp CE. Time to wake up! Am J Respir Crit Care Med. 2008; 177: 1291-2.

63. Maestrelli P, Boschetto P, Fabbri LM, Mapp C.E. Mechanism of occupational asthma. J Allergy Clin Immunol 2009; 123: 531-42.

64. Caramori G, Casolari P, Di Gregorio C, Saetta M, Baraldo S, Boschetto P, Ito K, Fabbri LM, Barnes PJ, Adcock IM, Cavallesco G, Chung KF, Papi A. MUC5AC expression is increased in bronchial submucosal glands of stable COPD patients. Histopathology 2009; 55: 321-31.

65. Mapp CE, Ferrazzoni S, Rizzo R, Miotto D, Stignani M, Boschetto P, Maestrelli P, Baricordi OR. Soluble HLA-G and interleukin-10 levels in isocyanate-induced asthma. Clin Exp Allergy 2009; 39: 812-9.

66. Miotto D, Lo Cascio N, Stendardo M, Querzoli P, Pedriali M, De Rosa E, Fabbri LM, Mapp CE, Boschetto P. CD8+ T cells expressing IL-10 are associated with a favourable prognosis in lung cancer. Lung Cancer 2010; 69: 355-60.

67. Boschetto P, Beghé B, Fabbri LM, Ceconi C. The link between COPD and coronary artery disease - implication for clinical practice. Respirology 2012;17:422-31.

68. Ziegler-Heitbrock L, Frankenberger M, Heimbeck I, Burggraf D, Wjst M, Häussinger K, Brightling C, Gupta S, Parr D, Subramanian D, Singh D, Kolsum U, Boschetto P, Potena A, Gorecka D, Nowinksi A, Barta I, Döme B, Strausz J, Greulich T, Vogelmeier C, Bals R, Hohlfeld J, Welte T, Venge P, Gut I, Boland A, Olaso R, Hager J, Hiemstra P, Rabe KF, Unmüßig M, Müller-Quernheim J, Prasse A. The EvA study: aims and strategy. Eur Respir J. 2012; 40:823-9.

69. Fabbri LM, Boyd C, Boschetto P, Rabe KF, Buist AS, Yawn B, Leff B, Kent DM, Schünemann HJ; on behalf of the ATS/ERS Ad Hoc Committee on Integrating and Coordinating Efforts in COPD Guideline Development. How to Integrate Multiple Comorbidities in Guideline Development: Article 10 in Integrating and Coordinating Efforts in COPD Guideline Development. An Official ATS/ERS Workshop Report. Proc Am Thorac Soc. 2012;9:274-281.

70. Lemiere C, Ameille J,Boschetto P, Labrecque M, Pralong JA. Occupational asthma: new deleterious agents at the workplace. Clin Chest Med. 2012 ;33:519-30.

71. Boschetto P, Fucili A, Stendardo M, Malagù M, Parrinello G, Casimirri E, Potena A, Ballerin L, Fabbri LM, Ferrari R, Ceconi C. Occurrence and impact of chronic obstructive pulmonary disease in elderly patients with stable heart failure. Respirology 2013;18:125-30.

72. Boschetto P, Campo I, Stendardo M, Casimirri E, Tinelli C, Gorrini M, Ceconi C, Fucili A, Potena A, Papi A, Ballerin L, Fabbri L, Luisetti M. Plasma sRAGE and N-(carboxymethyl) lysine in patients with CHF and/or COPD. Eur J Clin Invest 2013;43:562-9.

73. Beghé B, Verduri A, Bottazzi B, Stendardo M, Fucili A, Balduzzi S, Leuzzi C, Papi A, Mantovani A, Fabbri LM, Ceconi C, Boschetto P. Echocardiography, spirometry, and systemic acute-phase inflammatory proteins in smokers with COPD or CHF: an observational study. PLoS One. 2013;8

74. Nozzoli C, Beghè B, Boschetto P, Fabbri LM. Identifying and treating COPD in cardiac patients. Chest 2013;144:723-6.

75. Clini EM, Boschetto P, Lainscak M, Janssens W. Comorbidities in chronic obstructive pulmonary disease from assessment to treatment. Biomed Res Int. 2014;2014:414928

76. Casimirri E, Vaccari A, Schito M, Bonci M, Stendardo M, Stefanati A, Nardini M, Boschetto P. Chronic diseases are strongly associated with sickness absences in a sample of Italian public employees. Int J Occup Med Environ Health. 2014;27(3):343-54.

77. Stefanati A, Boschetto P, Previato S, Kuhdari P, De Paris P, Nardini M, Gabutti G. A survey on injuries among nurses and nursing students: a descriptive epidemiological analysis between 2002 and 2012 in a University Hospital. Med Lav. 2015;106(3):216-29.

78. Baraniuk JN, Casado B, Pannell LK, McGarvey PB, Boschetto P, Luisetti M, Iadarola P. Protein networks in induced sputum from smokers and COPD patients. Int J Chron Obstruct Pulmon Dis.
2015;10:1957-75.

79. Boschetto P, Vaccari A, Groccia R, Casimirri E, Stendardo M, Maietti E, Volpato S, Sarcone M, Fucili A. Forced expiratory volume in one second: Predicting return to work within 3months after chronic heart failure diagnosis. Int J Cardiol. 2015;203:798-799.

80. Casimirri E, Stendardo M, Bonci M, Andreoli R, Bottazzi B, Leone R, Schito M, Vaccari A, Papi A, Contoli M, Corradi M, Boschetto P. Biomarkers of oxidative-stress and inflammation in exhaled breath condensate from hospital cleaners. Biomarkers. 2016;21:115-22.

81. Subramanian DR, Gupta S, Burggraf D, Vom Silberberg SJ, Heimbeck I, Heiss-Neumann MS, Haeussinger K, Newby C, Hargadon B, Raj V, Singh D, Kolsum U, Hofer TP, Al-Shair K, Luetzen N, Prasse A, Müller-Quernheim J, Benea G, Leprotti S, Boschetto P, Gorecka D, Nowinski A, Oniszh K, Castell WZ, Hagen M, Barta I, Döme B, Strausz J, Greulich T, Vogelmeier C, Koczulla AR, Gut I, Hohlfeld J, Welte T, Lavae-Mokhtari M, Ziegler-Heitbrock L, Brightling C, Parr DG. Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography. Eur Respir J. 2016;48:92-103.

82. Bononi I, Comar M, Puozzo A, Stendardo M, Boschetto P, Orecchia S, Libener R, Guaschino R, Pietrobon S, Ferracin M, Negrini M, Martini F, Bovenzi M, Tognon M. Circulating microRNAs found dysregulated in ex-exposed asbestos workers and pleural mesothelioma patients as potential new biomarkers. Oncotarget. 2016; 7:82700-82711.

83. Pavanello S, Stendardo M, Mastrangelo G, Bonci M, Bottazzi B, Campisi M, Nardini M, Leone R, Mantovani A, Boschetto P. Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers. Front Immunol. 2017;8:516.

84. Engel M, Endesfelder D, Schloter-Hai B, Kublik S, Granitsiotis MS, Boschetto P, Stendardo M, Barta I, Dome B, Deleuze JF, Boland A, Müller-Quernheim J, Prasse A, Welte T, Hohlfeld J, Subramanian D, Parr D, Gut IG, Greulich T, Koczulla AR, Nowinski A, Gorecka D, Singh D, Gupta S, Brightling CE, Hoffmann H, Frankenberger M, Hofer TP, Burggraf D, Heiss-Neumann M, Ziegler-Heitbrock L, Schloter M, Zu Castell W. Ifluence of lung CT changes in chronic obstructive pulmonary disease (COPD) on the human lung microbiome. Plos One. 2017; 12:e0180859.